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| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | E2F1 | Transcription factor E2F1. (431 aa) |
| | CDH1 | Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. (882 aa) |
| | HGF | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (730 aa) |
| | CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) |
| | FGF3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa) |
| | FZD1 | Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (648 aa) |
| | GRB2 | Growth factor receptor-bound protein 2 isoform X1. (217 aa) |
| | E2F2 | Transcription factor E2F2. (442 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1281 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | GADD45B | Growth arrest and DNA damage-inducible protein GADD45 beta. (161 aa) |
| | SHC2 | SHC-transforming protein 2. (586 aa) |
| | FGF22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa) |
| | APC2 | Adenomatous polyposis coli protein 2. (2267 aa) |
| | WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | TGFB1 | Transforming growth factor beta-1. (287 aa) |
| | SHC4 | SHC-transforming protein 4. (630 aa) |
| | ARAF | Serine/threonine-protein kinase A-Raf. (606 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | WNT8A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa) |
| | BCL2 | Apoptosis regulator Bcl-2. (235 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) |
| | DVL2 | Segment polarity protein dishevelled homolog DVL-2 isoform X1. (734 aa) |
| | FZD9 | Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (597 aa) |
| | TGFB3 | Transforming growth factor beta-3. (461 aa) |
| | RB1 | Retinoblastoma-associated protein. (936 aa) |
| | DDB2 | DNA damage-binding protein 2 isoform X1. (426 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (507 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | APC | Adenomatous polyposis coli protein isoform X1. (2844 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa) |
| | WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | FZD6 | Frizzled-6 isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa) |
| | WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa) |
| | WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa) |
| | AXIN1 | Axin-1. (867 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (461 aa) |
| | GSK3B | Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (726 aa) |
| | FZD5 | Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (590 aa) |
| | AXIN2 | Axin-2 isoform X1. (842 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | DVL3 | Segment polarity protein dishevelled homolog DVL-3 isoform X1. (716 aa) |
| | WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) |
| | WNT9A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa) |
| | GAB1 | GRB2-associated-binding protein 1 isoform X1. (724 aa) |
| | FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (270 aa) |
| | FZD2 | Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa) |
| | DVL1 | Segment polarity protein dishevelled homolog DVL-1 isoform X1. (693 aa) |
| | BAK1 | Bcl-2 homologous antagonist/killer. (211 aa) |
| | SOS2 | Son of sevenless homolog 2 isoform X1. (1333 aa) |
| | RXRG | Retinoic acid receptor RXR-gamma isoform X1. (463 aa) |
| | WNT2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa) |
| | MET | Hepatocyte growth factor receptor. (1382 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | FRAT1 | Proto-oncogene FRAT1. (280 aa) |
| | FRAT2 | GSK-3-binding protein FRAT2. (233 aa) |
| | FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) |
| | GADD45G | Growth arrest and DNA damage-inducible protein GADD45 gamma. (159 aa) |
| | SHC3 | SHC-transforming protein 3. (587 aa) |
| | SOS1 | Son of sevenless homolog 1 isoform X1. (1333 aa) |
| | JUP | Junction plakoglobin. (744 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | CCNE2 | G1/S-specific cyclin-E2; Belongs to the cyclin family. (404 aa) |
| | ABCB1 | Multidrug resistance protein 1 isoform X1. (1280 aa) |
| | LRP6 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa) |
| | CDKN1B | Cyclin-dependent kinase inhibitor 1B. (198 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2559 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) |
| | TERT | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1117 aa) |
| | FZD3 | Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | POLK | DNA polymerase kappa. (870 aa) |
| | CDH17 | Cadherin-17. (831 aa) |
| | E2F3 | Transcription factor E2F3 isoform X1. (468 aa) |
| | FZD4 | Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | CDX2 | Homeobox protein CDX-2 isoform X1. (311 aa) |
| | FGF21 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha isoform X1. (165 aa) |
| | BAX | Apoptosis regulator BAX isoform X1. (192 aa) |
| | LOC101367134 | GTPase HRas-like. (177 aa) |
| | TCF7L1 | Transcription factor 7-like 1. (586 aa) |
| | FZD10 | Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa) |
| | WNT7B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa) |
| | FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | REG4 | Regenerating islet-derived protein 4. (158 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (245 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa) |
| | FZD8 | Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (689 aa) |
| | CCNE1 | G1/S-specific cyclin-E1; Belongs to the cyclin family. (410 aa) |
| | CTNNB1 | Catenin beta-1 isoform X1. (781 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | CTNNA1 | Catenin alpha-1 isoform X1. (929 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) |
| | NRAS | GTPase NRas. (189 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (377 aa) |
| | MUC2 | Mucin-2. (3132 aa) |
| | CSNK1A1 | Casein kinase I isoform alpha isoform X1; Belongs to the protein kinase superfamily. (365 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (840 aa) |
| | SHC1 | SHC-transforming protein 1 isoform X1. (609 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1. (161 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1210 aa) |
| | RXRA | Retinoic acid receptor RXR-alpha isoform X1. (497 aa) |
| | CTNNA2 | Catenin alpha-2 isoform X1. (953 aa) |
| | FZD7 | Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa) |
| | LEF1 | Lymphoid enhancer-binding factor 1 isoform X1. (413 aa) |
| | MLH1 | DNA mismatch repair protein Mlh1 isoform X1. (759 aa) |
| | TCF7L2 | Transcription factor 7-like 2 isoform X1. (621 aa) |
| | BRAF | Serine/threonine-protein kinase B-raf. (772 aa) |
| | LRP5 | Low-density lipoprotein receptor-related protein 5. (1451 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1209 aa) |
| | RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa) |
