STRINGSTRING
RPS6KA6 RPS6KA6 LRRK2 LRRK2 TFEB TFEB FOXO3 FOXO3 MAPK10 MAPK10 MAP2K1 MAP2K1 CARD11 CARD11 LOC102747252 LOC102747252 NFATC3 NFATC3 PRKCH PRKCH LOC102739066 LOC102739066 EEF2K EEF2K DDIT4 DDIT4 DUSP7 DUSP7 MAPK7 MAPK7 MAP2K6 MAP2K6 PTPRR PTPRR TBC1D7 TBC1D7 MAP2K7 MAP2K7 SGK3 SGK3 SGK2 SGK2 PRKCQ PRKCQ YWHAB YWHAB MAPK12 MAPK12 MAPK8IP2 MAPK8IP2 MTOR MTOR CCM2 CCM2 CDC25C CDC25C FOXO4 FOXO4 DUSP1 DUSP1 PKN1 PKN1 MAPK8 MAPK8 AKT1 AKT1 TFE3 TFE3 PKN2 PKN2 SMYD3 SMYD3 MAP2K2 MAP2K2 DUSP6 DUSP6 LOC102730047 LOC102730047 SPRY4 SPRY4 MOS MOS AKT3 AKT3 RAF1 RAF1 RPS6KB1 RPS6KB1 LOC102736999 LOC102736999 MAP3K1 MAP3K1 LOC102730470 LOC102730470 BCL10 BCL10 CARD10 CARD10 MAP3K3 MAP3K3 DUSP8 DUSP8 RPS6KA3 RPS6KA3 SIRT3 SIRT3 LRRC56 LRRC56 RICTOR RICTOR MAP3K6 MAP3K6 MAPK1 MAPK1 LOC102750756 LOC102750756 MAPKAP1 MAPKAP1 PRR5 PRR5 DEPTOR DEPTOR LOC102742022 LOC102742022 FOXO6 FOXO6 MAP2K3 MAP2K3 LOC102732719 LOC102732719 PTPN5 PTPN5 MAP3K2 MAP3K2 GRB7 GRB7 YWHAH YWHAH LOC102738241 LOC102738241 LOC102732653 LOC102732653 PTPN7 PTPN7 PKN3 PKN3 LOC102737163 LOC102737163 LOC102744498 LOC102744498 FOXO1 FOXO1 MAPK8IP1 MAPK8IP1 AKT1S1 AKT1S1 LOC102735556 LOC102735556 RPS6KB2 RPS6KB2 LOC102731352 LOC102731352 LOC102736146 LOC102736146 MAPK11 MAPK11 LOC102749849 LOC102749849 CARD14 CARD14
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPS6KA6Ribosomal protein S6 kinase. (744 aa)
LRRK2Leucine-rich repeat serine/threonine-protein kinase 2. (2150 aa)
TFEBTranscription factor EB. (329 aa)
FOXO3Forkhead box protein O3. (672 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
CARD11Caspase recruitment domain-containing protein 11. (1146 aa)
LOC102747252Protein kinase C eta type-like. (89 aa)
NFATC3Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1075 aa)
PRKCHProtein kinase C eta type-like. (454 aa)
LOC102739066GTP-binding protein Rheb-like. (142 aa)
EEF2KEukaryotic elongation factor 2 kinase. (544 aa)
DDIT4DNA damage-inducible transcript 4 protein. (231 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (406 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
PTPRRReceptor-type tyrosine-protein phosphatase R isoform X1. (655 aa)
TBC1D7TBC1 domain family member 7 isoform X1. (293 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (435 aa)
SGK3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (490 aa)
SGK2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (367 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
YWHAB14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (244 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
MAPK8IP2c-Jun-amino-terminal kinase-interacting protein 2. (831 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
CCM2Malcavernin. (447 aa)
CDC25CM-phase inducer phosphatase 3 isoform X1. (473 aa)
FOXO4Forkhead box protein O4 isoform X1. (506 aa)
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
PKN1Serine/threonine-protein kinase N1. (796 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
AKT1Non-specific serine/threonine protein kinase. (518 aa)
TFE3Transcription factor E3 isoform X1. (571 aa)
PKN2Serine/threonine-protein kinase N2 isoform X1. (984 aa)
SMYD3Histone-lysine N-methyltransferase SMYD3. (190 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
LOC102730047Tuberin-like. (353 aa)
SPRY4Protein sprouty homolog 4. (299 aa)
MOSProto-oncogene serine/threonine-protein kinase mos; Belongs to the protein kinase superfamily. (348 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (418 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
RPS6KB1Non-specific serine/threonine protein kinase. (445 aa)
LOC102736999Dual specificity protein phosphatase 10-like; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (177 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1345 aa)
LOC102730470Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa)
BCL10B-cell lymphoma/leukemia 10 isoform X1. (233 aa)
CARD10Caspase recruitment domain-containing protein 10. (1029 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (600 aa)
DUSP8Dual specificity protein phosphatase 8. (394 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
SIRT3NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (373 aa)
LRRC56Leucine-rich repeat-containing protein 56. (554 aa)
RICTORRapamycin-insensitive companion of mTOR isoform X1. (1732 aa)
MAP3K6Mitogen-activated protein kinase kinase kinase 6. (1204 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (326 aa)
LOC10275075614-3-3 protein epsilon-like; Belongs to the 14-3-3 family. (233 aa)
MAPKAP1Target of rapamycin complex 2 subunit MAPKAP1. (122 aa)
PRR5Proline-rich protein 5. (293 aa)
DEPTORDEP domain-containing mTOR-interacting protein. (305 aa)
LOC10274202214-3-3 protein zeta/delta-like isoform X1; Belongs to the 14-3-3 family. (245 aa)
FOXO6Forkhead box protein O6. (397 aa)
MAP2K3Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
LOC102732719Ribosomal protein S6 kinase alpha-1-like. (200 aa)
PTPN5Tyrosine-protein phosphatase non-receptor type 5 isoform X1. (539 aa)
MAP3K2Mitogen-activated protein kinase kinase kinase 2. (540 aa)
GRB7Growth factor receptor-bound protein 7. (403 aa)
YWHAH14-3-3 protein eta; Belongs to the 14-3-3 family. (246 aa)
LOC102738241Mitogen-activated protein kinase kinase kinase 5-like. (795 aa)
LOC102732653Nuclear receptor subfamily 4 group A member 1-like. (306 aa)
PTPN7Tyrosine-protein phosphatase non-receptor type 7. (301 aa)
PKN3Serine/threonine-protein kinase N3. (889 aa)
LOC102737163Tyrosine-protein phosphatase non-receptor type 3-like. (442 aa)
LOC10274449814-3-3 protein theta-like; Belongs to the 14-3-3 family. (98 aa)
FOXO1Forkhead box protein O1-like. (418 aa)
MAPK8IP1c-Jun-amino-terminal kinase-interacting protein 1. (669 aa)
AKT1S1Proline-rich AKT1 substrate 1. (276 aa)
LOC102735556Mitogen-activated protein kinase 9-like. (134 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa)
LOC102731352Serine/threonine-protein kinase/endoribonuclease IRE1-like. (414 aa)
LOC1027361463-phosphoinositide-dependent protein kinase 1-like. (216 aa)
MAPK11Mitogen-activated protein kinase. (254 aa)
LOC102749849Microphthalmia-associated transcription factor-like. (181 aa)
CARD14LOW QUALITY PROTEIN: caspase recruitment domain family, member 14. (510 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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