STRINGSTRING
IL7 IL7 IL13RA2 IL13RA2 IFNB1 IFNB1 IL10 IL10 IL4 IL4 IL5 IL5 IL13 IL13 IL23R IL23R IL12RB2 IL12RB2 LOC102733973 LOC102733973 IFNGR2 IFNGR2 IL2 IL2 IL21 IL21 EBI3 EBI3 IL22 IL22 IFNG IFNG IL23A IL23A IL12B IL12B IL12A IL12A IL2RB IL2RB CSF2RB CSF2RB IL6 IL6 LOC102743741 LOC102743741 TSLP TSLP IL10RA IL10RA IL9 IL9 IL3RA IL3RA CRLF2 CRLF2 TYK2 TYK2 IL21R IL21R IL4R IL4R IFNAR1 IFNAR1 IL22RA1 IL22RA1 IL10RB IL10RB LOC102730926 LOC102730926 LOC102747745 LOC102747745 IL3 IL3 CSF2 CSF2 LOC102749847 LOC102749847
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (158 aa)
IL13RA2Interleukin-13 receptor subunit alpha-2. (386 aa)
IFNB1Interferon beta. (182 aa)
IL10Interleukin-10. (178 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (131 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
IL13Interleukin-13. (133 aa)
IL23RInterleukin-23 receptor. (631 aa)
IL12RB2Interleukin-12 receptor subunit beta-2. (851 aa)
LOC102733973Interleukin-5 receptor subunit alpha-like. (310 aa)
IFNGR2Interferon gamma receptor 2. (115 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (153 aa)
EBI3Interleukin-27 subunit beta. (226 aa)
IL22Interleukin-22 isoform X1. (179 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
IL23AInterleukin-23 subunit alpha. (210 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (279 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa)
IL2RBInterleukin-2 receptor subunit beta. (552 aa)
CSF2RBCytokine receptor common subunit beta. (902 aa)
IL6Interleukin-6 isoform X1. (212 aa)
LOC102743741Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
TSLPLOW QUALITY PROTEIN: thymic stromal lymphopoietin. (182 aa)
IL10RAInterleukin-10 receptor subunit alpha. (575 aa)
IL9Interleukin-9. (142 aa)
IL3RAInterleukin-3 receptor subunit alpha. (376 aa)
CRLF2Cytokine receptor-like factor 2. (216 aa)
TYK2Non-receptor tyrosine-protein kinase TYK2-like. (767 aa)
IL21RInterleukin-21 receptor. (542 aa)
IL4RInterleukin-4 receptor subunit alpha isoform X1. (797 aa)
IFNAR1Interferon alpha/beta receptor 1. (560 aa)
IL22RA1Interleukin-22 receptor subunit alpha-1-like. (379 aa)
IL10RBInterleukin-10 receptor subunit beta. (375 aa)
LOC102730926Granulocyte-macrophage colony-stimulating factor receptor subunit alpha-like. (345 aa)
LOC102747745Interleukin-9 receptor-like. (175 aa)
IL3Interleukin-3. (143 aa)
CSF2Granulocyte-macrophage colony-stimulating factor. (153 aa)
LOC102749847Tyrosine-protein kinase JAK1-like. (444 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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