(27 nodes) Chemokine receptors bind chemokines network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CXCL12	Stromal cell-derived factor 1 isoform X1; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
	IL8	Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (104 aa)
	PPBP	LOW QUALITY PROTEIN: platelet basic protein. (119 aa)
	PF4	C-X-C motif chemokine. (106 aa)
	CXCL6	C-X-C motif chemokine. (113 aa)
	CCL24	c-C motif chemokine 24. (119 aa)
	CCL26	C-C motif chemokine. (94 aa)
	ACKR3	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa)
	CXCR5	c-X-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (377 aa)
	CCL13	C-C motif chemokine. (98 aa)
	CCL8	c-C motif chemokine 8. (99 aa)
	LOC102747594	c-X-C chemokine receptor type 4-like; Belongs to the G-protein coupled receptor 1 family. (353 aa)
	CXCL13	c-X-C motif chemokine 13. (110 aa)
	CXCL9	C-X-C motif chemokine. (126 aa)
	CXCL10	C-X-C motif chemokine. (98 aa)
	LOC102740920	C-C motif chemokine. (91 aa)
	CXCL11	c-X-C motif chemokine 11. (100 aa)
	CXCL14	c-X-C motif chemokine 14. (99 aa)
	LOC102734017	c-X-C chemokine receptor type 2-like; Belongs to the G-protein coupled receptor 1 family. (351 aa)
	LOC102735431	C-C motif chemokine. (93 aa)
	CCL17	c-C motif chemokine 17. (99 aa)
	CXCR3	c-X-C chemokine receptor type 3; Belongs to the G-protein coupled receptor 1 family. (364 aa)
	CCR3	c-C chemokine receptor type 3; Belongs to the G-protein coupled receptor 1 family. (359 aa)
	CCR1	c-C chemokine receptor type 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
	CCR5	c-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (352 aa)
	LOC102733354	c-X-C chemokine receptor type 2-like; Belongs to the G-protein coupled receptor 1 family. (356 aa)
	LOC102742576	C-X-C motif chemokine. (107 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACKR3	CXCL10	A0A2U3Y5X3	A0A2U3YK42	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine.	0.633
ACKR3	CXCL11	A0A2U3Y5X3	A0A2U3YKH5	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	c-X-C motif chemokine 11.	0.916
ACKR3	CXCL12	A0A2U3Y5X3	A0A2U3X9U4	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	Stromal cell-derived factor 1 isoform X1; Belongs to the intercrine alpha (chemokine CxC) family.	0.997
ACKR3	CXCL13	A0A2U3Y5X3	A0A2U3YIF7	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	c-X-C motif chemokine 13.	0.568
ACKR3	CXCL6	A0A2U3Y5X3	A0A2U3XEV9	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine.	0.547
ACKR3	CXCL9	A0A2U3Y5X3	A0A2U3YK39	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine.	0.547
ACKR3	CXCR5	A0A2U3Y5X3	A0A2U3YD64	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	c-X-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family.	0.542
ACKR3	LOC102740920	A0A2U3Y5X3	A0A2U3YKC3	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine.	0.480
ACKR3	LOC102742576	A0A2U3Y5X3	A0A2U3Z7N1	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine.	0.472
ACKR3	LOC102747594	A0A2U3Y5X3	A0A2U3YFN5	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	c-X-C chemokine receptor type 4-like; Belongs to the G-protein coupled receptor 1 family.	0.965
ACKR3	PPBP	A0A2U3Y5X3	A0A2U3XEG4	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	LOW QUALITY PROTEIN: platelet basic protein.	0.473
CCL13	CCL17	A0A2U3YD71	A0A2U3YY27	C-C motif chemokine.	c-C motif chemokine 17.	0.472
CCL13	CCL24	A0A2U3YD71	A0A2U3XR83	C-C motif chemokine.	c-C motif chemokine 24.	0.996
CCL13	CCL26	A0A2U3YD71	A0A2U3XRB4	C-C motif chemokine.	C-C motif chemokine.	0.994
CCL13	CCL8	A0A2U3YD71	A0A2U3YD74	C-C motif chemokine.	c-C motif chemokine 8.	0.985
CCL13	CCR1	A0A2U3YD71	A0A2U3Z4L1	C-C motif chemokine.	c-C chemokine receptor type 1; Belongs to the G-protein coupled receptor 1 family.	0.913
CCL13	CCR3	A0A2U3YD71	A0A2U3Z3V1	C-C motif chemokine.	c-C chemokine receptor type 3; Belongs to the G-protein coupled receptor 1 family.	0.949
CCL13	CCR5	A0A2U3YD71	A0A2U3Z4P7	C-C motif chemokine.	c-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family.	0.878
CCL13	CXCL10	A0A2U3YD71	A0A2U3YK42	C-C motif chemokine.	C-X-C motif chemokine.	0.970
CCL13	CXCL11	A0A2U3YD71	A0A2U3YKH5	C-C motif chemokine.	c-X-C motif chemokine 11.	0.966