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| | PMS1 | PMS1 protein homolog 1 isoform X1. (929 aa) |
| | FANCM | Fanconi anemia group M protein. (2050 aa) |
| | RECQL5 | ATP-dependent DNA helicase Q5. (408 aa) |
| | NEIL3 | Endonuclease 8-like 3. (651 aa) |
| | ERCC4 | DNA repair endonuclease XPF. (916 aa) |
| | CDC7 | Cell division cycle 7-related protein kinase isoform X1. (575 aa) |
| | DNA2 | DNA replication ATP-dependent helicase/nuclease DNA2. (1061 aa) |
| | RFC3 | Replication factor C subunit 3. (356 aa) |
| | FANCL | E3 ubiquitin-protein ligase FANCL isoform X1. (375 aa) |
| | BRCA2 | Breast cancer type 2 susceptibility protein homolog. (2818 aa) |
| | MUTYH | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (519 aa) |
| | RAD54L | DNA repair and recombination protein RAD54-like. (747 aa) |
| | NEIL2 | Endonuclease 8-like 2. (334 aa) |
| | TDRD3 | Tudor domain-containing protein 3-like isoform X1. (651 aa) |
| | POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa) |
| | TIPIN | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (184 aa) |
| | DBF4 | Protein DBF4 homolog A isoform X1. (676 aa) |
| | RAD54B | DNA repair and recombination protein RAD54B isoform X1. (911 aa) |
| | LOC102732047 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (540 aa) |
| | POLA1 | DNA polymerase. (1423 aa) |
| | PALB2 | Partner and localizer of BRCA2. (1183 aa) |
| | APEX1 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (317 aa) |
| | MPG | DNA-3-methyladenine glycosylase. (267 aa) |
| | HUS1 | Checkpoint protein; Belongs to the HUS1 family. (280 aa) |
| | CLSPN | Claspin isoform X1. (1340 aa) |
| | GINS3 | DNA replication complex GINS protein PSF3 isoform X1. (216 aa) |
| | GEN1 | Flap endonuclease GEN homolog 1. (907 aa) |
| | MSH4 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (858 aa) |
| | LOC102746870 | Chromosome transmission fidelity protein 8 homolog. (117 aa) |
| | SLX1A | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. (274 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) |
| | LOC102735468 | Mediator of DNA damage checkpoint protein 1-like. (738 aa) |
| | RBBP8 | DNA endonuclease RBBP8. (758 aa) |
| | RAD50 | DNA repair protein RAD50. (973 aa) |
| | FBXO18 | F-box only protein 18. (972 aa) |
| | LOC102740480 | DNA replication complex GINS protein PSF2-like. (114 aa) |
| | RAD51C | DNA repair protein RAD51 homolog 3-like. (371 aa) |
| | POLE3 | DNA polymerase epsilon subunit 3. (147 aa) |
| | MCM8 | DNA helicase MCM8 isoform X1; Belongs to the MCM family. (833 aa) |
| | REV3L | DNA polymerase zeta catalytic subunit. (3024 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | RAD1 | Cell cycle checkpoint protein RAD1. (281 aa) |
| | POLE4 | DNA polymerase epsilon subunit 4. (116 aa) |
| | POLD2 | DNA polymerase delta subunit 2. (469 aa) |
| | RPA3 | Replication protein A 14 kDa subunit. (121 aa) |
| | WDHD1 | WD repeat and HMG-box DNA-binding protein 1. (1129 aa) |
| | MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1362 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (951 aa) |
| | FANCE | Fanconi anemia group E protein. (468 aa) |
| | POLA2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (595 aa) |
| | MSH5 | mutS protein homolog 5 isoform X2. (832 aa) |
| | ORC5 | Origin recognition complex subunit 5. (435 aa) |
| | ERCC1 | DNA excision repair protein ERCC-1. (293 aa) |
| | LOC102748176 | Fanconi anemia-associated protein of 24 kDa. (224 aa) |
| | RAD17 | Cell cycle checkpoint protein RAD17. (634 aa) |
| | FANCD2 | Fanconi anemia group D2 protein. (511 aa) |
| | OGG1 | N-glycosylase/DNA lyase isoform X2. (334 aa) |
| | FANCG | Fanconi anemia group G protein. (626 aa) |
| | TDP2 | tyrosyl-DNA phosphodiesterase 2. (358 aa) |
| | FANCB | Fanconi anemia group B protein. (867 aa) |
| | EME1 | Crossover junction endonuclease EME1 isoform X1. (579 aa) |
| | LOC102731077 | Fanconi anemia group I protein-like. (252 aa) |
| | LIG4 | DNA ligase. (911 aa) |
| | TIMELESS | Protein timeless homolog. (1212 aa) |
| | MCPH1 | Microcephalin. (851 aa) |
| | MCM9 | DNA helicase MCM9; Belongs to the MCM family. (898 aa) |
| | RHNO1 | RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 isoform X1. (255 aa) |
| | NTHL1 | Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (314 aa) |
| | MEIOB | Meiosis-specific with OB domain-containing protein. (300 aa) |
| | TELO2 | Telomere length regulation protein TEL2 homolog. (822 aa) |
| | EME2 | Probable crossover junction endonuclease EME2. (324 aa) |
| | LOC102739117 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (187 aa) |
| | RAD51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (267 aa) |
| | ANKRD32 | Ankyrin repeat domain-containing protein 32 isoform X1. (1057 aa) |
| | XPA | DNA repair protein complementing XP-A cells. (273 aa) |
| | LOC102746412 | Replication protein A 32 kDa subunit-like. (124 aa) |
| | RFC4 | Replication factor C subunit 4. (363 aa) |
| | POLD4 | DNA polymerase delta subunit 4. (107 aa) |
| | TOP3B | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (316 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3054 aa) |
| | POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa) |
| | RMI1 | recQ-mediated genome instability protein 1. (638 aa) |
| | NEIL1 | Endonuclease 8-like 1. (383 aa) |
| | PRIMPOL | Coiled-coil domain-containing protein 111. (557 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (734 aa) |
| | DSCC1 | Sister chromatid cohesion protein DCC1. (392 aa) |
| | XRCC2 | DNA repair protein XRCC2. (280 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2277 aa) |
| | MLH3 | DNA mismatch repair protein Mlh3 isoform X1. (1460 aa) |
| | PWWP2A | PWWP domain-containing protein 2A. (755 aa) |
| | LOC102725847 | Uncharacterized protein LOC102725847. (1550 aa) |
| | RFC2 | Replication factor C subunit 2 isoform X1. (368 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (559 aa) |
| | FANCA | Fanconi anemia group A protein. (1453 aa) |
| | GINS4 | DNA replication complex GINS protein SLD5. (162 aa) |
| | PMS2 | Mismatch repair endonuclease PMS2. (859 aa) |
| | EXO1 | LOW QUALITY PROTEIN: exonuclease 1. (793 aa) |
| | LOC102732340 | DNA-(Apurinic or apyrimidinic site) lyase 2-like. (90 aa) |
| | MSH3 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1126 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (155 aa) |
| | LOC102730711 | DNA replication licensing factor MCM2-like. (149 aa) |
| | LOC102748019 | DNA replication licensing factor MCM3-like; Belongs to the MCM family. (605 aa) |
| | LOC102739655 | DNA replication licensing factor MCM3-like. (177 aa) |
| | PPP2R3B | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta. (596 aa) |
| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (391 aa) |
| | LOC102744185 | tyrosyl-DNA phosphodiesterase 1-like. (361 aa) |
| | RFC5 | Replication factor C subunit 5 isoform X1. (340 aa) |
| | UBE2T | Ubiquitin-conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family. (197 aa) |
| | LOC102732741 | uracil-DNA glycosylase-like. (177 aa) |
| | SNRPB | Small nuclear ribonucleoprotein-associated protein. (231 aa) |
| | LOC102739775 | Breast cancer type 1 susceptibility protein homolog. (471 aa) |
| | ATRIP | ATR-interacting protein. (597 aa) |
| | LOC102750135 | DNA helicase MCM9-like. (234 aa) |
| | ORC6 | Origin recognition complex subunit 6. (252 aa) |
| | LOC102733263 | Double-strand break repair protein MRE11A-like. (83 aa) |
| | LOC102733454 | DNA-(Apurinic or apyrimidinic site) lyase 2-like. (344 aa) |
| | LOC102728609 | Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (205 aa) |
| | SPRTN | sprT-like domain-containing protein Spartan. (484 aa) |
| | LOC102746675 | DNA primase small subunit-like. (156 aa) |
| | LOC102748344 | asparagine--tRNA ligase, cytoplasmic-like. (348 aa) |
