(5 nodes) HhH-GPD domain, and U7 snRNP network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NEIL3	Endonuclease 8-like 3. (651 aa)
	MUTYH	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (519 aa)
	OGG1	N-glycosylase/DNA lyase isoform X2. (334 aa)
	NTHL1	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (314 aa)
	SNRPB	Small nuclear ribonucleoprotein-associated protein. (231 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MUTYH	NEIL3	A0A2U3XC60	A0A2U3XAT2	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	Endonuclease 8-like 3.	0.770
MUTYH	NTHL1	A0A2U3XC60	A0A2U3YE14	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	0.891
MUTYH	OGG1	A0A2U3XC60	A0A2U3Y5R8	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	N-glycosylase/DNA lyase isoform X2.	0.951
MUTYH	SNRPB	A0A2U3XC60	A0A2U3Z394	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	Small nuclear ribonucleoprotein-associated protein.	0.677
NEIL3	MUTYH	A0A2U3XAT2	A0A2U3XC60	Endonuclease 8-like 3.	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	0.770
NEIL3	NTHL1	A0A2U3XAT2	A0A2U3YE14	Endonuclease 8-like 3.	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	0.910
NEIL3	OGG1	A0A2U3XAT2	A0A2U3Y5R8	Endonuclease 8-like 3.	N-glycosylase/DNA lyase isoform X2.	0.868
NTHL1	MUTYH	A0A2U3YE14	A0A2U3XC60	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	0.891
NTHL1	NEIL3	A0A2U3YE14	A0A2U3XAT2	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	Endonuclease 8-like 3.	0.910
NTHL1	OGG1	A0A2U3YE14	A0A2U3Y5R8	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	N-glycosylase/DNA lyase isoform X2.	0.725
NTHL1	SNRPB	A0A2U3YE14	A0A2U3Z394	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	Small nuclear ribonucleoprotein-associated protein.	0.733
OGG1	MUTYH	A0A2U3Y5R8	A0A2U3XC60	N-glycosylase/DNA lyase isoform X2.	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	0.951
OGG1	NEIL3	A0A2U3Y5R8	A0A2U3XAT2	N-glycosylase/DNA lyase isoform X2.	Endonuclease 8-like 3.	0.868
OGG1	NTHL1	A0A2U3Y5R8	A0A2U3YE14	N-glycosylase/DNA lyase isoform X2.	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	0.725
OGG1	SNRPB	A0A2U3Y5R8	A0A2U3Z394	N-glycosylase/DNA lyase isoform X2.	Small nuclear ribonucleoprotein-associated protein.	0.680
SNRPB	MUTYH	A0A2U3Z394	A0A2U3XC60	Small nuclear ribonucleoprotein-associated protein.	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	0.677
SNRPB	NTHL1	A0A2U3Z394	A0A2U3YE14	Small nuclear ribonucleoprotein-associated protein.	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	0.733
SNRPB	OGG1	A0A2U3Z394	A0A2U3Y5R8	Small nuclear ribonucleoprotein-associated protein.	N-glycosylase/DNA lyase isoform X2.	0.680