STRINGSTRING
CHD1 CHD1 SETDB1 SETDB1 ZNF143 ZNF143 MTF2 MTF2 NASP NASP KMT2D KMT2D HDAC9 HDAC9 LOC102742931 LOC102742931 LOC102743244 LOC102743244 LOC102739262 LOC102739262 PHF8 PHF8 FAM60A FAM60A MTA2 MTA2 EZH2 EZH2 PRDM2 PRDM2 DPY30 DPY30 HAT1 HAT1 LOC102749250 LOC102749250 LOC102731039 LOC102731039 MBD2 MBD2 LOC102728923 LOC102728923 LOC102750808 LOC102750808 HDAC1 HDAC1 SETBP1 SETBP1 IRF1 IRF1 CXXC1 CXXC1 SUV39H2 SUV39H2 LOC102742187 LOC102742187 LOC102744317 LOC102744317 LOC102746979 LOC102746979 LOC102747282 LOC102747282 LOC102739804 LOC102739804 LOC102749658 LOC102749658 LOC102751118 LOC102751118 LOC102726286 LOC102726286 LOC102727819 LOC102727819 LOC102746084 LOC102746084 LOC102750817 LOC102750817 LOC102728431 LOC102728431 EED EED LOC102732990 LOC102732990 RBBP7 RBBP7 LOC102737083 LOC102737083 LOC102738290 LOC102738290 LOC102738582 LOC102738582 SUDS3 SUDS3 LOC102746189 LOC102746189 MEN1 MEN1 KDM1A KDM1A LOC102738587 LOC102738587 CHD4 CHD4 AEBP2 AEBP2 SETD1A SETD1A LOC102750824 LOC102750824 HDAC5 HDAC5 HMG20B HMG20B KDM6B KDM6B LOC102727422 LOC102727422 LOC102726804 LOC102726804 ARID3C ARID3C HDAC7 HDAC7 NYNRIN NYNRIN BRMS1 BRMS1 HDAC8 HDAC8 HDAC4 HDAC4 SMYD1 SMYD1 CAMKMT CAMKMT ASF1A ASF1A SETMAR SETMAR WDR73 WDR73 LOC102734598 LOC102734598 KMT2B KMT2B LOC102745380 LOC102745380 WDR5B WDR5B LOC102738010 LOC102738010 HDAC2 HDAC2 SETD7 SETD7 GATAD2B GATAD2B RCOR3 RCOR3 SAP30L SAP30L GATAD2A GATAD2A PHF6 PHF6 SMYD2 SMYD2 LOC102731297 LOC102731297 CHAF1B CHAF1B RCOR2 RCOR2 LOC102732330 LOC102732330 JARID2 JARID2 SUV420H2 SUV420H2 LOC102750992 LOC102750992 LOC102750685 LOC102750685 LOC102726670 LOC102726670 LOC102725568 LOC102725568 LOC102730207 LOC102730207 LOC102729806 LOC102729806 ING2 ING2 SMYD5 SMYD5 LOC102730819 LOC102730819 LOC102744100 LOC102744100 LOC102745317 LOC102745317 LOC102743792 LOC102743792 LOC102745625 LOC102745625 LOC102745013 LOC102745013 LOC102746847 LOC102746847 SIN3B SIN3B EZH1 EZH1 LOC102749930 LOC102749930 PHF21A PHF21A LOC102743898 LOC102743898 LOC102730119 LOC102730119 ASF1B ASF1B CDK2AP1 CDK2AP1 LOC102737969 LOC102737969 LOC102738770 LOC102738770
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHD1chromodomain-helicase-DNA-binding protein 1 isoform X1. (1797 aa)
SETDB1Histone-lysine N-methyltransferase SETDB1 isoform X1. (1297 aa)
ZNF143Zinc finger protein 143 isoform X1. (638 aa)
MTF2Metal-response element-binding transcription factor 2 isoform X1. (593 aa)
NASPNuclear autoantigenic sperm protein. (771 aa)
KMT2DHistone-lysine N-methyltransferase 2D. (5552 aa)
HDAC9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1065 aa)
LOC102742931UPF0547 protein C16orf87 homolog. (156 aa)
LOC102743244Histone-lysine N-methyltransferase SETMAR-like. (180 aa)
LOC102739262Histone-lysine N-methyltransferase SETD1A-like. (299 aa)
PHF8Histone lysine demethylase PHF8-like isoform X4. (1024 aa)
FAM60AProtein FAM60A. (221 aa)
MTA2Metastasis-associated protein MTA2 isoform X1. (668 aa)
EZH2Histone-lysine N-methyltransferase EZH2. (144 aa)
PRDM2PR domain zinc finger protein 2. (1634 aa)
DPY30Protein dpy-30 homolog isoform X1. (99 aa)
HAT1Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (419 aa)
LOC102749250Breast cancer metastasis-suppressor 1-like protein-like isoform X1. (323 aa)
LOC102731039Histone H3.3-like. (128 aa)
MBD2methyl-CpG-binding domain protein 2. (212 aa)
LOC102728923Activating transcription factor 7-interacting protein 1-like. (337 aa)
LOC102750808Histone H2A; Belongs to the histone H2A family. (129 aa)
HDAC1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
SETBP1SET-binding protein-like. (1596 aa)
IRF1Interferon regulatory factor. (322 aa)
CXXC1cpG-binding protein isoform X2. (655 aa)
SUV39H2Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (410 aa)
LOC102742187Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102744317Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102746979Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC102747282Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC102739804Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102749658Histone H2A; Belongs to the histone H2A family. (140 aa)
LOC102751118Histone H2A; Belongs to the histone H2A family. (128 aa)
LOC102726286Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (78 aa)
LOC102727819Histone H2A; Belongs to the histone H2A family. (117 aa)
LOC102746084Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC102750817Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102728431Histone H2B; Belongs to the histone H2B family. (119 aa)
EEDPolycomb protein EED isoform X1. (466 aa)
LOC102732990Histone H2A; Belongs to the histone H2A family. (140 aa)
RBBP7Histone-binding protein RBBP7 isoform X1. (469 aa)
LOC102737083Histone H3; Belongs to the histone H3 family. (136 aa)
LOC102738290Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102738582Histone H2A; Belongs to the histone H2A family. (130 aa)
SUDS3Sin3 histone deacetylase corepressor complex component SDS3. (328 aa)
LOC102746189Histone H2A; Belongs to the histone H2A family. (102 aa)
MEN1Menin. (616 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
LOC102738587Histone H2B subacrosomal variant-like; Belongs to the histone H2B family. (122 aa)
CHD4chromodomain-helicase-DNA-binding protein 4 isoform X2. (1912 aa)
AEBP2Zinc finger protein AEBP2 isoform X1. (513 aa)
SETD1AHistone-lysine N-methyltransferase SETD1A-like. (1384 aa)
LOC102750824Histone-lysine N-methyltransferase EZH1-like. (522 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1116 aa)
HMG20Bannotation not available (317 aa)
KDM6BLysine-specific demethylase 6B. (1559 aa)
LOC102727422Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC102726804Histone H2B; Belongs to the histone H2B family. (126 aa)
ARID3CAT-rich interactive domain-containing protein 3C. (413 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (928 aa)
NYNRINProtein NYNRIN. (1894 aa)
BRMS1Breast cancer metastasis-suppressor 1. (246 aa)
HDAC8Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (415 aa)
HDAC4Histone deacetylase 4-like. (667 aa)
SMYD1Histone-lysine N-methyltransferase SMYD1. (490 aa)
CAMKMTCalmodulin-lysine N-methyltransferase. (277 aa)
ASF1AHistone chaperone ASF1A. (204 aa)
SETMARLOW QUALITY PROTEIN: histone-lysine N-methyltransferase SETMAR. (321 aa)
WDR73WD repeat-containing protein 73. (370 aa)
LOC102734598Histone-lysine N-methyltransferase SUV420H1-like. (225 aa)
KMT2BHistone-lysine N-methyltransferase 2B. (2635 aa)
LOC102745380Histone-lysine N-methyltransferase EZH2-like. (556 aa)
WDR5BWD repeat-containing protein 5B. (306 aa)
LOC102738010Uncharacterized protein C17orf96 homolog. (379 aa)
HDAC2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa)
SETD7Histone-lysine N-methyltransferase SETD7. (307 aa)
GATAD2BTranscriptional repressor p66-beta. (593 aa)
RCOR3REST corepressor 3 isoform X1. (552 aa)
SAP30LHistone deacetylase complex subunit SAP30L isoform X1. (182 aa)
GATAD2ATranscriptional repressor p66-alpha isoform X1. (543 aa)
PHF6PHD finger protein 6 isoform X1. (366 aa)
SMYD2N-lysine methyltransferase SMYD2. (198 aa)
LOC102731297Histone H2A; Belongs to the histone H2A family. (117 aa)
CHAF1BChromatin assembly factor 1 subunit B. (549 aa)
RCOR2REST corepressor 2. (479 aa)
LOC102732330Histone H3; Belongs to the histone H3 family. (136 aa)
JARID2Protein Jumonji. (1075 aa)
SUV420H2Histone-lysine N-methyltransferase SUV420H2. (461 aa)
LOC102750992Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC102750685Histone H2A; Belongs to the histone H2A family. (131 aa)
LOC102726670Histone H2A; Belongs to the histone H2A family. (131 aa)
LOC102725568Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC102730207Histone H2A; Belongs to the histone H2A family. (143 aa)
LOC102729806WD repeat-containing protein 5-like. (334 aa)
ING2Inhibitor of growth protein. (280 aa)
SMYD5SET and MYND domain-containing protein 5. (418 aa)
LOC102730819Histone H3; Belongs to the histone H3 family. (136 aa)
LOC102744100Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC102745317Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102743792Histone H2A; Belongs to the histone H2A family. (129 aa)
LOC102745625Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC102745013Histone H3; Belongs to the histone H3 family. (136 aa)
LOC102746847Histone H2B; Belongs to the histone H2B family. (126 aa)
SIN3BPaired amphipathic helix protein Sin3b. (875 aa)
EZH1Histone-lysine N-methyltransferase EZH1. (209 aa)
LOC102749930AT-rich interactive domain-containing protein 5B-like. (216 aa)
PHF21APHD finger protein 21A-like isoform X1. (312 aa)
LOC102743898Histone H2B type W-T-like; Belongs to the histone H2B family. (174 aa)
LOC102730119set1/Ash2 histone methyltransferase complex subunit ASH2-like. (220 aa)
ASF1BHistone chaperone ASF1B. (189 aa)
CDK2AP1Cyclin-dependent kinase 2-associated protein 1. (87 aa)
LOC102737969Histone H2A; Belongs to the histone H2A family. (66 aa)
LOC102738770PHD finger protein 21A-like. (243 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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