(13 nodes) cGMP binding, and Calcium sensitive guanylate cyclase activator activity network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CNGB3	Cyclic nucleotide-gated cation channel beta-3. (780 aa)
	GUCA1A	Guanylyl cyclase-activating protein 1. (205 aa)
	GUCA1B	Guanylyl cyclase-activating protein 2. (201 aa)
	PDE6H	Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma. (83 aa)
	GUCY2D	Guanylate cyclase. (865 aa)
	CNGA1	cGMP-gated cation channel alpha-1. (694 aa)
	PDE6C	Phosphodiesterase. (709 aa)
	GNAT2	Guanine nucleotide-binding protein G(T) subunit alpha-2 isoform X2. (359 aa)
	KIRREL2	Kin of IRRE-like protein 2. (635 aa)
	LOC102740621	Guanylate cyclase. (1124 aa)
	CNGA4	Cyclic nucleotide-gated cation channel alpha-4. (575 aa)
	LOC102748639	Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta-like. (577 aa)
	CNGA2	Cyclic nucleotide-gated olfactory channel. (659 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNGA1	CNGB3	A0A2U3Y9B0	A0A2U3X6S1	cGMP-gated cation channel alpha-1.	Cyclic nucleotide-gated cation channel beta-3.	0.969
CNGA1	GNAT2	A0A2U3Y9B0	A0A2U3YGN1	cGMP-gated cation channel alpha-1.	Guanine nucleotide-binding protein G(T) subunit alpha-2 isoform X2.	0.650
CNGA1	GUCA1A	A0A2U3Y9B0	A0A2U3XCP7	cGMP-gated cation channel alpha-1.	Guanylyl cyclase-activating protein 1.	0.796
CNGA1	GUCA1B	A0A2U3Y9B0	A0A2U3XD47	cGMP-gated cation channel alpha-1.	Guanylyl cyclase-activating protein 2.	0.605
CNGA1	LOC102748639	A0A2U3Y9B0	A0A2U3Z3Q1	cGMP-gated cation channel alpha-1.	Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta-like.	0.613
CNGA1	PDE6C	A0A2U3Y9B0	A0A2U3YEJ3	cGMP-gated cation channel alpha-1.	Phosphodiesterase.	0.502
CNGA1	PDE6H	A0A2U3Y9B0	A0A2U3XQU8	cGMP-gated cation channel alpha-1.	Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma.	0.487
CNGA2	CNGA4	A0A2U3Z5P4	A0A2U3YV13	Cyclic nucleotide-gated olfactory channel.	Cyclic nucleotide-gated cation channel alpha-4.	0.980
CNGA2	CNGB3	A0A2U3Z5P4	A0A2U3X6S1	Cyclic nucleotide-gated olfactory channel.	Cyclic nucleotide-gated cation channel beta-3.	0.924
CNGA2	GNAT2	A0A2U3Z5P4	A0A2U3YGN1	Cyclic nucleotide-gated olfactory channel.	Guanine nucleotide-binding protein G(T) subunit alpha-2 isoform X2.	0.532
CNGA2	GUCA1A	A0A2U3Z5P4	A0A2U3XCP7	Cyclic nucleotide-gated olfactory channel.	Guanylyl cyclase-activating protein 1.	0.407
CNGA2	GUCA1B	A0A2U3Z5P4	A0A2U3XD47	Cyclic nucleotide-gated olfactory channel.	Guanylyl cyclase-activating protein 2.	0.467
CNGA2	GUCY2D	A0A2U3Z5P4	A0A2U3Y5K5	Cyclic nucleotide-gated olfactory channel.	Guanylate cyclase.	0.499
CNGA2	KIRREL2	A0A2U3Z5P4	A0A2U3YH51	Cyclic nucleotide-gated olfactory channel.	Kin of IRRE-like protein 2.	0.742
CNGA2	LOC102740621	A0A2U3Z5P4	A0A2U3YP41	Cyclic nucleotide-gated olfactory channel.	Guanylate cyclase.	0.499
CNGA2	PDE6C	A0A2U3Z5P4	A0A2U3YEJ3	Cyclic nucleotide-gated olfactory channel.	Phosphodiesterase.	0.511
CNGA4	CNGA2	A0A2U3YV13	A0A2U3Z5P4	Cyclic nucleotide-gated cation channel alpha-4.	Cyclic nucleotide-gated olfactory channel.	0.980
CNGA4	CNGB3	A0A2U3YV13	A0A2U3X6S1	Cyclic nucleotide-gated cation channel alpha-4.	Cyclic nucleotide-gated cation channel beta-3.	0.928
CNGA4	GNAT2	A0A2U3YV13	A0A2U3YGN1	Cyclic nucleotide-gated cation channel alpha-4.	Guanine nucleotide-binding protein G(T) subunit alpha-2 isoform X2.	0.533
CNGA4	GUCA1A	A0A2U3YV13	A0A2U3XCP7	Cyclic nucleotide-gated cation channel alpha-4.	Guanylyl cyclase-activating protein 1.	0.407