STRINGSTRING
PIK3R3 PIK3R3 IRS1 IRS1 PTPN11 PTPN11 GRB10 GRB10 JAK2 JAK2 LOC102749673 LOC102749673 PTPN2 PTPN2 EPOR EPOR PIK3CA PIK3CA LOC102736516 LOC102736516 JAK3 JAK3 LOC102731850 LOC102731850 LOC102740654 LOC102740654 LOC102748833 LOC102748833 LOC102751021 LOC102751021 LOC102750030 LOC102750030
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
IRS1Insulin receptor substrate 1-like isoform X1. (1236 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
GRB10Growth factor receptor-bound protein 10. (586 aa)
JAK2Tyrosine-protein kinase. (952 aa)
LOC102749673Insulin-like growth factor 1 receptor-like. (143 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type 2. (289 aa)
EPORErythropoietin receptor; Receptor for erythropoietin. (509 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC102736516Phosphatidylinositol 3-kinase regulatory subunit alpha-like. (138 aa)
JAK3Tyrosine-protein kinase. (1139 aa)
LOC102731850Tyrosine-protein kinase receptor. (757 aa)
LOC102740654Phosphoinositide 3-kinase regulatory subunit 5-like. (111 aa)
LOC102748833Tyrosine-protein kinase. (375 aa)
LOC102751021Phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1. (454 aa)
LOC102750030Protein-tyrosine kinase 2-beta-like. (125 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
Server load: low (32%) [HD]