STRINGSTRING
SEMA3D SEMA3D SEMA3A SEMA3A SEMA3C SEMA3C SFRP2 SFRP2 JADE1 JADE1 SEMA6D SEMA6D GJA1 GJA1 LOC102727565 LOC102727565 SEMA6C SEMA6C ST7L ST7L PTPRJ PTPRJ RIMS1 RIMS1 PTCH2 PTCH2 IGFBPL1 IGFBPL1 OSGIN2 OSGIN2 LOC102750498 LOC102750498 DCSTAMP DCSTAMP LOC102732138 LOC102732138 GREM1 GREM1 LOC102728392 LOC102728392 CDKL3 CDKL3 KAZALD1 KAZALD1 SPG20 SPG20 IGF1 IGF1 SEMA3G SEMA3G BAP1 BAP1 CDKN2C CDKN2C LOC102749254 LOC102749254 DCBLD2 DCBLD2 CDKN1B CDKN1B IP6K2 IP6K2 NME6 NME6 MAP3K13 MAP3K13 RERG RERG SEMA4C SEMA4C TMC8 TMC8 LOC102735672 LOC102735672 LOC102732272 LOC102732272 HNF4A HNF4A NUBP1 NUBP1 BMPR2 BMPR2 GDF9 GDF9 SMAD4 SMAD4 ADAM15 ADAM15 LOC102735085 LOC102735085 TP53TG5 TP53TG5 SOCS2 SOCS2 MTOR MTOR LOC102751226 LOC102751226 LOC102726900 LOC102726900 SMARCA2 SMARCA2 SYT4 SYT4 RBBP7 RBBP7 SRF SRF LAMTOR2 LAMTOR2 LOC102730452 LOC102730452 RYK RYK MYL2 MYL2 PLAA PLAA BCL6 BCL6 SEMA3F SEMA3F MFSD2A MFSD2A ING4 ING4 NKX6-1 NKX6-1 OSTN OSTN MUL1 MUL1 DDX3X DDX3X TGFB2 TGFB2 ZFYVE27 ZFYVE27 EPB41L3 EPB41L3 LOC102745362 LOC102745362 SLC44A4 SLC44A4 TP53 TP53 CRLF3 CRLF3 LOC102740904 LOC102740904 ARMC12 ARMC12 NGF NGF PLXNA3 PLXNA3 SFN SFN SYT2 SYT2 DNAJB2 DNAJB2 OSGIN1 OSGIN1 SESN2 SESN2 LOC102746290 LOC102746290 CCDC85B CCDC85B EXOSC9 EXOSC9 SEMA7A SEMA7A ISLR ISLR ISLR2 ISLR2 RB1 RB1 CIRBP CIRBP POU4F2 POU4F2 BARHL2 BARHL2 PML PML CDKN2D CDKN2D CCAR2 CCAR2 DCUN1D5 DCUN1D5 PSRC1 PSRC1 SOX17 SOX17 LGI1 LGI1 IST1 IST1 ADNP2 ADNP2 LOC102747306 LOC102747306 CGRRF1 CGRRF1 WNT11 WNT11 SERTAD1 SERTAD1 SERTAD3 SERTAD3 ACVRL1 ACVRL1 WNT3A WNT3A UCN UCN WNT3 WNT3 SEMA5A SEMA5A MSX1 MSX1 FBP1 FBP1 KIAA1598 KIAA1598 SYT17 SYT17 YJEFN3 YJEFN3 FLCN FLCN CRKL CRKL NDUFA13 NDUFA13 COMMD5 COMMD5 GOLGA4 GOLGA4 DDR1 DDR1 SEMA6A SEMA6A SPHK2 SPHK2 EXOSC4 EXOSC4 DCUN1D3 DCUN1D3 EXOSC2 EXOSC2 IGFBP4 IGFBP4 GNG4 GNG4 RTN4R RTN4R SEMA4G SEMA4G GNB2L1 GNB2L1 KIAA1024 KIAA1024 MMP14 MMP14 TSG101 TSG101 SFRP1 SFRP1 KRT17 KRT17 LOC102737030 LOC102737030 NOV NOV LOC102739340 LOC102739340 USP47 USP47 TRIM32 TRIM32 TGFB1 TGFB1 INHBA INHBA YAP1 YAP1 SYT3 SYT3 CDHR2 CDHR2 LOC102732425 LOC102732425 LOC102743039 LOC102743039 LOC102729898 LOC102729898 LOC102738536 LOC102738536 LOC102731623 LOC102731623 NTN1 NTN1 MEGF8 MEGF8 DDX49 DDX49 KAT7 KAT7 LOC102750402 LOC102750402 LOC102726456 LOC102726456 SEMA6B SEMA6B LOC102736634 LOC102736634 ABL1 ABL1 PPP1R9B PPP1R9B CRYAA CRYAA KDM2B KDM2B LOC102749531 LOC102749531 PSMD10 PSMD10 LOC102740049 LOC102740049 WT1 WT1 LOC102749626 LOC102749626 CDKN2AIP CDKN2AIP LOC102730318 LOC102730318 GSK3A GSK3A ZNF639 ZNF639 INO80 INO80 IFRD2 IFRD2 SEMA3B SEMA3B NOL12 NOL12 SEMA5B SEMA5B UNC13A UNC13A CDKN1A CDKN1A CPNE5 CPNE5 LOC102743583 LOC102743583 LOC102727190 LOC102727190 LOC102740078 LOC102740078 CDK5 CDK5 SEMA4A SEMA4A LOC102729518 LOC102729518 FRZB FRZB
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SEMA3DLOW QUALITY PROTEIN: semaphorin-3D; Belongs to the semaphorin family. (781 aa)
SEMA3Asemaphorin-3A; Belongs to the semaphorin family. (772 aa)
SEMA3Csemaphorin-3C; Belongs to the semaphorin family. (696 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
JADE1Protein Jade-1 isoform X1. (843 aa)
SEMA6Dsemaphorin-6D-like isoform X3; Belongs to the semaphorin family. (1017 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
LOC102727565Galactokinase-like. (208 aa)
SEMA6Csemaphorin-6C isoform X1; Belongs to the semaphorin family. (963 aa)
ST7LSuppressor of tumorigenicity 7 protein-like. (499 aa)
PTPRJReceptor-type tyrosine-protein phosphatase eta-like. (1218 aa)
RIMS1Regulating synaptic membrane exocytosis protein 2 isoform X1. (931 aa)
PTCH2Protein patched homolog 2. (1207 aa)
IGFBPL1Insulin-like growth factor-binding protein-like 1. (172 aa)
OSGIN2Oxidative stress-induced growth inhibitor 2. (549 aa)
LOC102750498Casein kinase II subunit alpha-like isoform X1; Belongs to the protein kinase superfamily. (391 aa)
DCSTAMPDendritic cell-specific transmembrane protein. (470 aa)
LOC102732138Testis-specific Y-encoded-like protein 2-like; Belongs to the nucleosome assembly protein (NAP) family. (451 aa)
GREM1Gremlin. (184 aa)
LOC102728392ephrin-A5-like; Belongs to the ephrin family. (191 aa)
CDKL3Cyclin-dependent kinase-like 3 isoform X2. (590 aa)
KAZALD1Kazal-type serine protease inhibitor domain-containing protein 1. (302 aa)
SPG20Spartin isoform X1. (691 aa)
IGF1Insulin-like growth factor I isoform X1. (153 aa)
SEMA3Gsemaphorin-3G; Belongs to the semaphorin family. (770 aa)
BAP1Ubiquitin carboxyl-terminal hydrolase. (729 aa)
CDKN2CCyclin-dependent kinase 4 inhibitor C. (168 aa)
LOC102749254ATPase family AAA domain-containing protein 3-like. (591 aa)
DCBLD2Discoidin, CUB and LCCL domain-containing protein 2. (776 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (425 aa)
NME6Nucleoside diphosphate kinase. (186 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa)
RERGRas-related and estrogen-regulated growth inhibitor isoform X1. (199 aa)
SEMA4Csemaphorin-4C; Belongs to the semaphorin family. (833 aa)
TMC8Transmembrane channel-like protein. (723 aa)
LOC102735672Myotrophin-like. (118 aa)
LOC102732272Ragulator complex protein LAMTOR1-like. (152 aa)
HNF4AHepatocyte nuclear factor 4-alpha. (399 aa)
NUBP1Cytosolic Fe-S cluster assembly factor NUBP1. (219 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (974 aa)
GDF9Growth/differentiation factor 9. (453 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
ADAM15Disintegrin and metalloproteinase domain-containing protein 15 isoform X1. (867 aa)
LOC102735085semaphorin-4F-like; Belongs to the semaphorin family. (449 aa)
TP53TG5LOW QUALITY PROTEIN: TP53-target gene 5 protein. (278 aa)
SOCS2Suppressor of cytokine signaling 2. (198 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
LOC102751226Peptidase inhibitor 16-like. (304 aa)
LOC102726900Mothers against decapentaplegic homolog 7-like. (178 aa)
SMARCA2Probable global transcription activator SNF2L2 isoform X1. (278 aa)
SYT4Synaptotagmin-4-like isoform X1. (425 aa)
RBBP7Histone-binding protein RBBP7 isoform X1. (469 aa)
SRFSerum response factor. (508 aa)
LAMTOR2Ragulator complex protein LAMTOR2 isoform X1. (125 aa)
LOC102730452semaphorin-4A-like; Belongs to the semaphorin family. (436 aa)
RYKTyrosine-protein kinase RYK. (475 aa)
MYL2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform isoform X1. (166 aa)
PLAAPhospholipase A-2-activating protein. (639 aa)
BCL6B-cell lymphoma 6 protein. (706 aa)
SEMA3Fsemaphorin-3F isoform X1; Belongs to the semaphorin family. (786 aa)
MFSD2AMajor facilitator superfamily domain-containing protein 2A isoform X1. (529 aa)
ING4Inhibitor of growth protein. (249 aa)
NKX6-1Homeobox protein Nkx-6.1-like. (366 aa)
OSTNOsteocrin. (132 aa)
MUL1Mitochondrial ubiquitin ligase activator of NFKB 1. (352 aa)
DDX3XATP-dependent RNA helicase DDX3X-like isoform X1; Belongs to the DEAD box helicase family. (662 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
ZFYVE27Protrudin. (411 aa)
EPB41L3Band 4.1-like protein 3 isoform X1. (1095 aa)
LOC102745362Calsyntenin-3-like. (404 aa)
SLC44A4Choline transporter-like protein 4 isoform X1; Belongs to the CTL (choline transporter-like) family. (709 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
CRLF3Cytokine receptor-like factor 3. (438 aa)
LOC102740904Unconventional prefoldin RPB5 interactor-like. (458 aa)
ARMC12Armadillo repeat-containing protein 12 isoform X1. (367 aa)
NGFBeta-nerve growth factor; Belongs to the NGF-beta family. (241 aa)
PLXNA3plexin-A3. (1452 aa)
SFN14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa)
SYT2Synaptotagmin-2. (419 aa)
DNAJB2dnaJ homolog subfamily B member 2 isoform X2. (278 aa)
OSGIN1Oxidative stress-induced growth inhibitor 1. (478 aa)
SESN2Sestrin-2. (481 aa)
LOC10274629025-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial-like; Belongs to the cytochrome P450 family. (508 aa)
CCDC85BCoiled-coil domain-containing protein 85B. (202 aa)
EXOSC9Exosome complex component RRP45. (440 aa)
SEMA7Asemaphorin-7A isoform X1; Belongs to the semaphorin family. (663 aa)
ISLRImmunoglobulin superfamily containing leucine-rich repeat protein. (426 aa)
ISLR2Immunoglobulin superfamily containing leucine-rich repeat protein 2. (746 aa)
RB1Retinoblastoma-associated protein. (846 aa)
CIRBPCold-inducible RNA-binding protein isoform X2. (172 aa)
POU4F2POU domain protein. (408 aa)
BARHL2barH-like 2 homeobox protein-like. (382 aa)
PMLProtein PML. (880 aa)
CDKN2DCyclin-dependent kinase 4 inhibitor D isoform X2. (166 aa)
CCAR2Cell cycle and apoptosis regulator protein 2. (918 aa)
DCUN1D5DCN1-like protein. (237 aa)
PSRC1Proline/serine-rich coiled-coil protein 1. (303 aa)
SOX17Transcription factor SOX-17-like. (406 aa)
LGI1Leucine-rich glioma-inactivated protein 1. (468 aa)
IST1IST1 homolog isoform X1. (364 aa)
ADNP2ADNP homeobox protein 2-like. (1134 aa)
LOC102747306hemK methyltransferase family member 2-like isoform X1. (214 aa)
CGRRF1Cell growth regulator with RING finger domain protein 1. (332 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
SERTAD1SERTA domain-containing protein 1 isoform X1. (237 aa)
SERTAD3SERTA domain-containing protein 3. (198 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
UCNUrocortin. (126 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (338 aa)
SEMA5Asemaphorin-5A-like. (1034 aa)
MSX1Homeobox protein MSX-1. (303 aa)
FBP1Fructose-1,6-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
KIAA1598Shootin-1 isoform X1. (631 aa)
SYT17Synaptotagmin-17. (474 aa)
YJEFN3yjeF N-terminal domain-containing protein 3. (250 aa)
FLCNFolliculin. (579 aa)
CRKLCrk-like protein. (303 aa)
NDUFA13NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13. (144 aa)
COMMD5COMM domain-containing protein 5. (224 aa)
GOLGA4Golgin subfamily A member 4 isoform X1. (2250 aa)
DDR1Epithelial discoidin domain-containing receptor 1 isoform X1. (921 aa)
SEMA6Asemaphorin-6A isoform X1; Belongs to the semaphorin family. (1047 aa)
SPHK2Sphingosine kinase 2 isoform X1. (656 aa)
EXOSC4Exosome complex component RRP41 isoform X1. (245 aa)
DCUN1D3DCN1-like protein. (304 aa)
EXOSC2Exosome complex component RRP4 isoform X1. (293 aa)
IGFBP4Insulin-like growth factor-binding protein 4. (258 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
RTN4RReticulon-4 receptor. (528 aa)
SEMA4Gsemaphorin-4G; Belongs to the semaphorin family. (840 aa)
GNB2L1Guanine nucleotide-binding protein subunit beta-2-like 1 isoform X1. (317 aa)
KIAA1024UPF0258 protein KIAA1024 homolog. (832 aa)
MMP14Matrix metalloproteinase-14. (582 aa)
TSG101Tumor susceptibility gene 101 protein isoform X1. (391 aa)
SFRP1Secreted frizzled-related protein 1. (303 aa)
KRT17Keratin, type I cytoskeletal 17; Belongs to the intermediate filament family. (436 aa)
LOC102737030Receptor tyrosine-protein kinase erbB-2-like; Belongs to the protein kinase superfamily. Tyr protein kinase family. (627 aa)
NOVProtein NOV homolog. (353 aa)
LOC102739340Oncomodulin-like; Belongs to the parvalbumin family. (109 aa)
USP47Ubiquitin carboxyl-terminal hydrolase 47; Belongs to the peptidase C19 family. (1287 aa)
TRIM32E3 ubiquitin-protein ligase TRIM32-like isoform X1. (655 aa)
TGFB1Transforming growth factor beta-1. (261 aa)
INHBAInhibin beta A chain. (424 aa)
YAP1Yorkie homolog. (326 aa)
SYT3Synaptotagmin-3. (544 aa)
CDHR2Cadherin-related family member 2. (1308 aa)
LOC102732425Myelin-associated glycoprotein-like. (382 aa)
LOC102743039Protein FAM122A-like. (287 aa)
LOC102729898NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial-like; Belongs to the complex I 30 kDa subunit family. (162 aa)
LOC102738536Insulin-like growth factor-binding protein 3-like. (120 aa)
LOC102731623Serine protease hepsin-like. (82 aa)
NTN1Netrin-1-like. (402 aa)
MEGF8Multiple epidermal growth factor-like domains protein 8. (2068 aa)
DDX49Probable ATP-dependent RNA helicase DDX49; Belongs to the DEAD box helicase family. (483 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)
LOC102750402E3 ubiquitin-protein ligase SMURF1-like. (321 aa)
LOC102726456Hepatoma-derived growth factor-related protein 2-like. (670 aa)
SEMA6Bsemaphorin-6B; Belongs to the semaphorin family. (673 aa)
LOC102736634NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial-like. (132 aa)
ABL1Tyrosine-protein kinase ABL1-like. (312 aa)
PPP1R9BNeurabin-2. (819 aa)
CRYAAAlpha-crystallin A chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (173 aa)
KDM2BLysine-specific demethylase 2B. (637 aa)
LOC102749531Growth/differentiation factor 2-like. (260 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
LOC102740049Testis-specific Y-encoded-like protein 2-like; Belongs to the nucleosome assembly protein (NAP) family. (278 aa)
WT1Wilms tumor protein-like. (413 aa)
LOC102749626Synaptotagmin-1-like. (303 aa)
CDKN2AIPCDKN2A-interacting protein. (582 aa)
LOC102730318Mothers against decapentaplegic homolog. (415 aa)
GSK3AGlycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (419 aa)
ZNF639Zinc finger protein 639. (485 aa)
INO80DNA helicase INO80-like. (350 aa)
IFRD2Interferon-related developmental regulator 2 isoform X2. (441 aa)
SEMA3Bsemaphorin-3B. (166 aa)
NOL12Nucleolar protein 12. (213 aa)
SEMA5Bsemaphorin-5B-like. (989 aa)
UNC13AProtein unc-13 homolog A. (1223 aa)
CDKN1ACyclin-dependent kinase inhibitor 1 isoform X1. (161 aa)
CPNE5Copine-5. (193 aa)
LOC102743583Nuclear apoptosis-inducing factor 1-like. (327 aa)
LOC102727190Serine/threonine-protein kinase STK11-like. (545 aa)
LOC102740078Ragulator complex protein LAMTOR1-like. (98 aa)
CDK5Cyclin-dependent kinase 5 isoform X1; Belongs to the protein kinase superfamily. (292 aa)
SEMA4Asemaphorin-4A-like. (350 aa)
LOC102729518Cytosolic Fe-S cluster assembly factor NUBP1-like. (109 aa)
FRZBSecreted frizzled-related protein 3-like. (306 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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