STRINGSTRING
TNS1 TNS1 LPXN LPXN STARD13 STARD13 PIK3R3 PIK3R3 GREM1 GREM1 SEMA3G SEMA3G SNAI1 SNAI1 GIPC2 GIPC2 ILK ILK PTEN PTEN LOC102734862 LOC102734862 ANLN ANLN CORO1C CORO1C EPHB4 EPHB4 SEMA4C SEMA4C CORO1A CORO1A HTR2B HTR2B CDH13 CDH13 EMP2 EMP2 ACVR1 ACVR1 S100Z S100Z PTPN11 PTPN11 SRF SRF LAMTOR2 LAMTOR2 LOC102730452 LOC102730452 AMOTL2 AMOTL2 PPARD PPARD SEMA3F SEMA3F ITGB1 ITGB1 PRKX PRKX ADTRP ADTRP PKN1 PKN1 GIPC1 GIPC1 LGALS8 LGALS8 HIF1A HIF1A PKN2 PKN2 GIPC3 GIPC3 LTB4R2 LTB4R2 KITLG KITLG SOX8 SOX8 GPLD1 GPLD1 PTP4A3 PTP4A3 PHACTR4 PHACTR4 LOC102734979 LOC102734979 CD248 CD248 SEMA7A SEMA7A LOC102750359 LOC102750359 PIP5K1A PIP5K1A RET RET LOC102746429 LOC102746429 ARSJ ARSJ SEMA6D SEMA6D ALX1 ALX1 SEMA3C SEMA3C SEMA3A SEMA3A SEMA3D SEMA3D CXCL13 CXCL13 RAB13 RAB13 CORO1B CORO1B SEMA6C SEMA6C SEMA5A SEMA5A MIXL1 MIXL1 KANK2 KANK2 CER1 CER1 PHOX2B PHOX2B ITGA4 ITGA4 FSTL1 FSTL1 WNT11 WNT11 SEMA6A SEMA6A FAT2 FAT2 PML PML PAFAH1B1 PAFAH1B1 EGR3 EGR3 LOC102750752 LOC102750752 GPR124 GPR124 ITGB7 ITGB7 RIC8A RIC8A SOX17 SOX17 LOC102730129 LOC102730129 LOC102737672 LOC102737672 LOC102729222 LOC102729222 SEMA4A SEMA4A LOC102745028 LOC102745028 LOC102742177 LOC102742177 LOC102725974 LOC102725974 RADIL RADIL LOC102746856 LOC102746856 LOC102727186 LOC102727186 LOC102728905 LOC102728905 SEMA5B SEMA5B ARSI ARSI SEMA3B SEMA3B FGF2 FGF2 LOC102730108 LOC102730108 GBX2 GBX2 LOC102740057 LOC102740057 LOC102737253 LOC102737253 PKN3 PKN3 LOC102740157 LOC102740157 FERMT1 FERMT1 ANXA6 ANXA6 SOX18 SOX18 ABL1 ABL1 LOC102745526 LOC102745526 SEMA6B SEMA6B MEGF8 MEGF8 MMRN2 MMRN2 SOX10 SOX10 S100A2 S100A2 AQP1 AQP1 TESK1 TESK1 SGPL1 SGPL1 NOV NOV KRT16 KRT16 LOC102743650 LOC102743650 SEMA4G SEMA4G LOC102729478 LOC102729478 MYH9 MYH9 PWWP2A PWWP2A NODAL NODAL LGALS12 LGALS12 LRG1 LRG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TNS1Tensin-1-like isoform X1. (1710 aa)
LPXNLeupaxin; Belongs to the paxillin family. (386 aa)
STARD13stAR-related lipid transfer protein 13. (1123 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
GREM1Gremlin. (184 aa)
SEMA3Gsemaphorin-3G; Belongs to the semaphorin family. (770 aa)
SNAI1Zinc finger protein SNAI1. (264 aa)
GIPC2PDZ domain-containing protein GIPC2. (312 aa)
ILKIntegrin-linked protein kinase isoform X1. (452 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
LOC102734862Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
ANLNActin-binding protein anillin isoform X1. (1087 aa)
CORO1Ccoronin-1C. (303 aa)
EPHB4Ephrin type-B receptor 4 isoform X1. (988 aa)
SEMA4Csemaphorin-4C; Belongs to the semaphorin family. (833 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
HTR2B5-hydroxytryptamine receptor 2B. (526 aa)
CDH13Cadherin-13-like. (512 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
S100ZProtein S100; Belongs to the S-100 family. (97 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
SRFSerum response factor. (508 aa)
LAMTOR2Ragulator complex protein LAMTOR2 isoform X1. (125 aa)
LOC102730452semaphorin-4A-like; Belongs to the semaphorin family. (436 aa)
AMOTL2Angiomotin-like protein 2 isoform X1. (776 aa)
PPARDPeroxisome proliferator-activated receptor delta isoform X1. (441 aa)
SEMA3Fsemaphorin-3F isoform X1; Belongs to the semaphorin family. (786 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
PRKXcAMP-dependent protein kinase catalytic subunit PRKX; Belongs to the protein kinase superfamily. (361 aa)
ADTRPAndrogen-dependent TFPI-regulating protein. (260 aa)
PKN1Serine/threonine-protein kinase N1. (796 aa)
GIPC1PDZ domain-containing protein GIPC1. (333 aa)
LGALS8Galectin. (357 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X1. (823 aa)
PKN2Serine/threonine-protein kinase N2 isoform X1. (984 aa)
GIPC3PDZ domain-containing protein GIPC3. (312 aa)
LTB4R2Leukotriene B4 receptor 2. (358 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (274 aa)
SOX8Transcription factor SOX-8. (412 aa)
GPLD1Phosphatidylinositol-glycan-specific phospholipase D. (840 aa)
PTP4A3Protein tyrosine phosphatase type IVA 3 isoform X1. (173 aa)
PHACTR4Phosphatase and actin regulator. (715 aa)
LOC102734979Cytochrome P450 1B1-like; Belongs to the cytochrome P450 family. (543 aa)
CD248Endosialin. (774 aa)
SEMA7Asemaphorin-7A isoform X1; Belongs to the semaphorin family. (663 aa)
LOC102750359Myosin-9-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (163 aa)
PIP5K1APhosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1. (549 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Belongs to the protein kinase superfamily. Tyr protein kinase family. (819 aa)
LOC102746429Na(+)/H(+) exchange regulatory cofactor NHE-RF1-like. (222 aa)
ARSJArylsulfatase J isoform X1. (600 aa)
SEMA6Dsemaphorin-6D-like isoform X3; Belongs to the semaphorin family. (1017 aa)
ALX1ALX homeobox protein 1. (326 aa)
SEMA3Csemaphorin-3C; Belongs to the semaphorin family. (696 aa)
SEMA3Asemaphorin-3A; Belongs to the semaphorin family. (772 aa)
SEMA3DLOW QUALITY PROTEIN: semaphorin-3D; Belongs to the semaphorin family. (781 aa)
CXCL13c-X-C motif chemokine 13. (110 aa)
RAB13Ras-related protein Rab-13. (203 aa)
CORO1BCoronin; Belongs to the WD repeat coronin family. (489 aa)
SEMA6Csemaphorin-6C isoform X1; Belongs to the semaphorin family. (963 aa)
SEMA5Asemaphorin-5A-like. (1034 aa)
MIXL1Homeobox protein MIXL1. (124 aa)
KANK2KN motif and ankyrin repeat domain-containing protein 2. (419 aa)
CER1Cerberus. (274 aa)
PHOX2BPaired mesoderm homeobox protein 2B. (285 aa)
ITGA4Integrin alpha-4; Belongs to the integrin alpha chain family. (1033 aa)
FSTL1Follistatin-related protein 1 isoform X1. (307 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
SEMA6Asemaphorin-6A isoform X1; Belongs to the semaphorin family. (1047 aa)
FAT2Protocadherin Fat 2. (2171 aa)
PMLProtein PML. (880 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha. (148 aa)
EGR3Early growth response protein 3 isoform X1. (387 aa)
LOC102750752Lysyl oxidase homolog 2-like. (126 aa)
GPR124G-protein coupled receptor 124; Belongs to the G-protein coupled receptor 2 family. (1332 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (763 aa)
RIC8Asynembryn-A isoform X2. (529 aa)
SOX17Transcription factor SOX-17-like. (406 aa)
LOC102730129Uncharacterized protein LOC102730129. (471 aa)
LOC102737672C-type lectin domain family 14 member A-like. (489 aa)
LOC102729222Schwannomin-interacting protein 1-like. (146 aa)
SEMA4Asemaphorin-4A-like. (350 aa)
LOC102745028Endothelin-1 receptor-like. (178 aa)
LOC102742177Mast/stem cell growth factor receptor Kit-like. (217 aa)
LOC102725974KN motif and ankyrin repeat domain-containing protein 1-like. (247 aa)
RADILRas-associating and dilute domain-containing protein. (1054 aa)
LOC102746856Platelet-activating factor acetylhydrolase IB subunit alpha-like isoform X1. (239 aa)
LOC102727186Heart- and neural crest derivatives-expressed protein 2-like. (217 aa)
LOC102728905KN motif and ankyrin repeat domain-containing protein 1-like. (167 aa)
SEMA5Bsemaphorin-5B-like. (989 aa)
ARSIArylsulfatase I. (575 aa)
SEMA3Bsemaphorin-3B. (166 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (113 aa)
LOC102730108Neuropilin-1-like. (465 aa)
GBX2Homeobox protein GBX-2. (251 aa)
LOC102740057Vascular endothelial growth factor A-like isoform X1; Belongs to the PDGF/VEGF growth factor family. (186 aa)
LOC102737253Glial cell line-derived neurotrophic factor-like isoform X1. (211 aa)
PKN3Serine/threonine-protein kinase N3. (889 aa)
LOC102740157Cadherin-5-like; Cadherins are calcium-dependent cell adhesion proteins. (464 aa)
FERMT1Fermitin family homolog 1-like. (678 aa)
ANXA6Annexin. (673 aa)
SOX18Transcription factor SOX-18. (186 aa)
ABL1Tyrosine-protein kinase ABL1-like. (312 aa)
LOC102745526Neurturin-like. (191 aa)
SEMA6Bsemaphorin-6B; Belongs to the semaphorin family. (673 aa)
MEGF8Multiple epidermal growth factor-like domains protein 8. (2068 aa)
MMRN2Multimerin-2-like. (799 aa)
SOX10Transcription factor SOX-10. (469 aa)
S100A2Protein S100; Belongs to the S-100 family. (97 aa)
AQP1Aquaporin-1 isoform X1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
TESK1Dual specificity testis-specific protein kinase 1. (628 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (568 aa)
NOVProtein NOV homolog. (353 aa)
KRT16Keratin, type I cytoskeletal 16 isoform X1; Belongs to the intermediate filament family. (427 aa)
LOC102743650AN1-type zinc finger protein 6-like. (181 aa)
SEMA4Gsemaphorin-4G; Belongs to the semaphorin family. (840 aa)
LOC102729478Endothelin-1 receptor-like; Belongs to the G-protein coupled receptor 1 family. (253 aa)
MYH9Myosin-9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1845 aa)
PWWP2APWWP domain-containing protein 2A. (755 aa)
NODALNodal homolog. (348 aa)
LGALS12Galectin. (314 aa)
LRG1Leucine-rich alpha-2-glycoprotein. (354 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
Server load: low (14%) [HD]