STRINGSTRING
FAM43A FAM43A QARS QARS NF1 NF1 LOC102750017 LOC102750017 SMCR8 SMCR8 LOC102744093 LOC102744093 LOC102730920 LOC102730920 LOC102740547 LOC102740547 LOC102743045 LOC102743045 PARD6A PARD6A ABL1 ABL1 CTDSP1 CTDSP1 UBASH3B UBASH3B CBLC CBLC LOC102738536 LOC102738536 NCK2 NCK2 LOC102739346 LOC102739346 EPHA1 EPHA1 LOC102729692 LOC102729692 SOCS5 SOCS5 TGFB1 TGFB1 GGNBP2 GGNBP2 SMPD1 SMPD1 PARK7 PARK7 SH3GL2 SH3GL2 PYCARD PYCARD NOG NOG RABGEF1 RABGEF1 KAT2B KAT2B GREM1 GREM1 SH3BP5L SH3BP5L LOC102749335 LOC102749335 PLK1 PLK1 DDIT4 DDIT4 PPP1R15B PPP1R15B LAX1 LAX1 ERRFI1 ERRFI1 DGKQ DGKQ CEP85 CEP85 SFRP1 SFRP1 TSG101 TSG101 LOC102729387 LOC102729387 GNB2L1 GNB2L1 CDKN2A CDKN2A CDKN2B CDKN2B DEPTOR DEPTOR PAQR3 PAQR3 LOC102744874 LOC102744874 LOC102741824 LOC102741824 LDLRAD4 LDLRAD4 PTPRQ PTPRQ PPM1E PPM1E HMGCR HMGCR PKIG PKIG GADD45A GADD45A RASSF2 RASSF2 SAMSN1 SAMSN1 LATS1 LATS1 PID1 PID1 LOC102749183 LOC102749183 INCA1 INCA1 EMILIN1 EMILIN1 KIRREL2 KIRREL2 PRKAG2 PRKAG2 BMP7 BMP7 PMEPA1 PMEPA1 FAM102B FAM102B PRKAR1A PRKAR1A FAM72A FAM72A PPP4R2 PPP4R2 TTC36 TTC36 LRRK1 LRRK1 INPP5K INPP5K SPRY1 SPRY1 CTDSPL CTDSPL CDKN2D CDKN2D LOC102747590 LOC102747590 IMPACT IMPACT PIBF1 PIBF1 RB1 RB1 LOC102736999 LOC102736999 LOC102727937 LOC102727937 IFNG IFNG THY1 THY1 CBL CBL TRIB1 TRIB1 JUN JUN SPRY4 SPRY4 SIRT2 SIRT2 DUSP6 DUSP6 SMYD3 SMYD3 CACTIN CACTIN LOC102737090 LOC102737090 CAMK2N1 CAMK2N1 FAM43B FAM43B BAK1 BAK1 PKN1 PKN1 MVP MVP ITGB1BP1 ITGB1BP1 MYADM MYADM PRKAR1B PRKAR1B LOC102739096 LOC102739096 LOC102751229 LOC102751229 DMTN DMTN CRKL CRKL TFAP4 TFAP4 NUP62 NUP62 PRNP PRNP PIP5KL1 PIP5KL1 PTPN2 PTPN2 LOC102749493 LOC102749493 PPM1F PPM1F BDKRB2 BDKRB2 HEXIM1 HEXIM1 LOC102732879 LOC102732879 SOCS4 SOCS4 ATG14 ATG14 LOC102726900 LOC102726900 CAV3 CAV3 SPRY3 SPRY3 DUSP7 DUSP7 CDKN2C CDKN2C PRKAR2B PRKAR2B PTPRB PTPRB DVL1 DVL1 LOC102740025 LOC102740025 HGF HGF FABP4 FABP4 DKK2 DKK2 SFRP2 SFRP2 PKIA PKIA CDK5RAP1 CDK5RAP1 LRRK2 LRRK2 LATS2 LATS2 PRKCZ PRKCZ PTEN PTEN LRP6 LRP6 NCK1 NCK1 CD300A CD300A CBLB CBLB PTPRJ PTPRJ CD109 CD109 PAX6 PAX6 CAV1 CAV1 CDKN1B CDKN1B PRKAR2A PRKAR2A CORO1C CORO1C MAS1 MAS1 RGS14 RGS14 WWTR1 WWTR1 INPP5J INPP5J DNAJC3 DNAJC3 LOC102731771 LOC102731771 PTPRO PTPRO HHEX HHEX HSPB1 HSPB1 PPP4C PPP4C SOCS3 SOCS3 ADAR ADAR GBA GBA TNFAIP3 TNFAIP3 LOC102750518 LOC102750518 LOC102736765 LOC102736765 CAMK2N2 CAMK2N2 LOC102736146 LOC102736146 LOC102735151 LOC102735151 LOC102748833 LOC102748833 CDKN1A CDKN1A AKT1S1 AKT1S1 LOC102738369 LOC102738369 VPS25 VPS25 DBNDD1 DBNDD1 BMP2 BMP2 AGT AGT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FAM43AProtein FAM43A. (431 aa)
QARSglutamine--tRNA ligase isoform X2; Belongs to the class-I aminoacyl-tRNA synthetase family. (775 aa)
NF1Neurofibromin-like. (1269 aa)
LOC102750017Mothers against decapentaplegic homolog 6-like. (181 aa)
SMCR8smith-Magenis syndrome chromosomal region candidate gene 8 protein. (937 aa)
LOC102744093WW domain-containing transcription regulator protein 1-like. (286 aa)
LOC102730920Periodic tryptophan protein 1 homolog. (166 aa)
LOC102740547Bone morphogenetic protein 4-like isoform X1. (409 aa)
LOC102743045Disabled homolog 2-interacting protein-like. (326 aa)
PARD6APartitioning defective 6 homolog alpha isoform X1. (346 aa)
ABL1Tyrosine-protein kinase ABL1-like. (312 aa)
CTDSP1Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform X2. (261 aa)
UBASH3BUbiquitin-associated and SH3 domain-containing protein B. (592 aa)
CBLCE3 ubiquitin-protein ligase CBL-C. (496 aa)
LOC102738536Insulin-like growth factor-binding protein 3-like. (120 aa)
NCK2Cytoplasmic protein. (380 aa)
LOC102739346Dysbindin-like. (159 aa)
EPHA1Ephrin type-A receptor 1. (976 aa)
LOC102729692Ras-interacting protein 1-like. (208 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
TGFB1Transforming growth factor beta-1. (261 aa)
GGNBP2Gametogenetin-binding protein 2 isoform X1. (740 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (625 aa)
PARK7Protein DJ-1 isoform X1. (189 aa)
SH3GL2endophilin-A1. (352 aa)
PYCARDApoptosis-associated speck-like protein containing a CARD isoform X1. (194 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
RABGEF1Rab5 GDP/GTP exchange factor. (491 aa)
KAT2BHistone acetyltransferase KAT2B. (735 aa)
GREM1Gremlin. (184 aa)
SH3BP5LSH3 domain-binding protein 5-like. (385 aa)
LOC102749335E3 ubiquitin-protein ligase CBL-B-like. (139 aa)
PLK1Serine/threonine-protein kinase PLK. (604 aa)
DDIT4DNA damage-inducible transcript 4 protein. (231 aa)
PPP1R15BProtein phosphatase 1 regulatory subunit 15B. (711 aa)
LAX1LOW QUALITY PROTEIN: lymphocyte transmembrane adapter 1. (432 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (460 aa)
DGKQDiacylglycerol kinase. (913 aa)
CEP85Centrosomal protein of 85 kDa. (768 aa)
SFRP1Secreted frizzled-related protein 1. (303 aa)
TSG101Tumor susceptibility gene 101 protein isoform X1. (391 aa)
LOC102729387F-box only protein 7-like. (300 aa)
GNB2L1Guanine nucleotide-binding protein subunit beta-2-like 1 isoform X1. (317 aa)
CDKN2ACyclin-dependent kinase inhibitor 2A, isoforms 1/2/3. (152 aa)
CDKN2BCyclin-dependent kinase 4 inhibitor B. (138 aa)
DEPTORDEP domain-containing mTOR-interacting protein. (305 aa)
PAQR3Progestin and adipoQ receptor family member 3 isoform X2. (311 aa)
LOC102744874Protein FAM102B-like. (206 aa)
LOC102741824Dysbindin-like. (250 aa)
LDLRAD4Low-density lipoprotein receptor class A domain-containing protein 4 isoform X1. (269 aa)
PTPRQPhosphatidylinositol phosphatase PTPRQ. (2300 aa)
PPM1EProtein phosphatase 1E. (756 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (887 aa)
PKIGcAMP-dependent protein kinase inhibitor gamma. (75 aa)
GADD45AGrowth arrest and DNA damage-inducible protein GADD45 alpha isoform X1. (165 aa)
RASSF2Ras association domain-containing protein 2. (271 aa)
SAMSN1SAM domain-containing protein SAMSN-1 isoform X1. (442 aa)
LATS1Serine/threonine-protein kinase LATS1. (1127 aa)
PID1PTB-containing, cubilin and LRP1-interacting protein. (203 aa)
LOC102749183Fibulin-1-like. (624 aa)
INCA1Protein INCA1. (251 aa)
EMILIN1EMILIN-1-like. (1013 aa)
KIRREL2Kin of IRRE-like protein 2. (635 aa)
PRKAG25'-AMP-activated protein kinase subunit gamma-2-like isoform X2. (327 aa)
BMP7Bone morphogenetic protein 7-like. (312 aa)
PMEPA1Transmembrane prostate androgen-induced protein. (237 aa)
FAM102BProtein FAM102B. (219 aa)
PRKAR1AcAMP-dependent protein kinase type I-alpha regulatory subunit. (381 aa)
FAM72AProtein FAM72A. (149 aa)
PPP4R2Serine/threonine-protein phosphatase 4 regulatory subunit 2 isoform X1. (464 aa)
TTC36Tetratricopeptide repeat protein 36. (189 aa)
LRRK1Leucine-rich repeat serine/threonine-protein kinase 1. (576 aa)
INPP5KInositol polyphosphate 5-phosphatase K isoform X1. (452 aa)
SPRY1Protein sprouty homolog 1 isoform X1. (319 aa)
CTDSPLCTD small phosphatase-like protein. (119 aa)
CDKN2DCyclin-dependent kinase 4 inhibitor D isoform X2. (166 aa)
LOC102747590Sprouty-related, EVH1 domain-containing protein 2-like. (220 aa)
IMPACTProtein IMPACT isoform X1. (318 aa)
PIBF1Progesterone-induced-blocking factor 1. (757 aa)
RB1Retinoblastoma-associated protein. (846 aa)
LOC102736999Dual specificity protein phosphatase 10-like; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (177 aa)
LOC102727937Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2-like. (249 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
THY1Thy-1 membrane glycoprotein. (161 aa)
CBLE3 ubiquitin-protein ligase CBL. (910 aa)
TRIB1Tribbles homolog 1. (292 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (335 aa)
SPRY4Protein sprouty homolog 4. (299 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
SMYD3Histone-lysine N-methyltransferase SMYD3. (190 aa)
CACTINCactin. (749 aa)
LOC102737090Sortilin-related receptor-like. (446 aa)
CAMK2N1Calcium/calmodulin-dependent protein kinase II inhibitor 1. (78 aa)
FAM43BProtein FAM43B. (209 aa)
BAK1Bcl-2 homologous antagonist/killer. (211 aa)
PKN1Serine/threonine-protein kinase N1. (796 aa)
MVPMajor vault protein. (890 aa)
ITGB1BP1Integrin beta-1-binding protein 1 isoform X1. (200 aa)
MYADMMyeloid-associated differentiation marker. (322 aa)
PRKAR1BcAMP-dependent protein kinase type I-beta regulatory subunit. (145 aa)
LOC102739096Protein C9orf72 homolog. (235 aa)
LOC102751229Zinc finger protein RFP-like isoform X1. (513 aa)
DMTNDematin isoform X1. (405 aa)
CRKLCrk-like protein. (303 aa)
TFAP4Transcription factor AP-4. (337 aa)
NUP62Nuclear pore glycoprotein p62. (525 aa)
PRNPMajor prion protein; Belongs to the prion family. (257 aa)
PIP5KL1Phosphatidylinositol 4-phosphate 5-kinase-like protein 1. (396 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type 2. (289 aa)
LOC102749493Zinc finger CCCH-type with G patch domain-containing protein-like. (194 aa)
PPM1FProtein phosphatase 1F. (287 aa)
BDKRB2B2 bradykinin receptor; Belongs to the G-protein coupled receptor 1 family. (392 aa)
HEXIM1Protein HEXIM1. (359 aa)
LOC102732879Disabled homolog 2-interacting protein-like. (454 aa)
SOCS4Suppressor of cytokine signaling 4. (440 aa)
ATG14Beclin 1-associated autophagy-related key regulator. (492 aa)
LOC102726900Mothers against decapentaplegic homolog 7-like. (178 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
SPRY3Protein sprouty homolog 3. (288 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (406 aa)
CDKN2CCyclin-dependent kinase 4 inhibitor C. (168 aa)
PRKAR2BcAMP-dependent protein kinase type II-beta regulatory subunit. (417 aa)
PTPRBReceptor-type tyrosine-protein phosphatase beta. (1997 aa)
DVL1Segment polarity protein dishevelled homolog DVL-1 isoform X1. (693 aa)
LOC102740025Protein sprouty homolog 2-like isoform X1. (315 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (730 aa)
FABP4Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
DKK2Dickkopf-related protein 2. (259 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
PKIAcAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (76 aa)
CDK5RAP1CDK5 regulatory subunit-associated protein 1 isoform X1. (583 aa)
LRRK2Leucine-rich repeat serine/threonine-protein kinase 2. (2150 aa)
LATS2Non-specific serine/threonine protein kinase. (1084 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (557 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
NCK1Cytoplasmic protein. (377 aa)
CD300ACMRF35-like molecule 8. (309 aa)
CBLBE3 ubiquitin-protein ligase CBL-B-like. (832 aa)
PTPRJReceptor-type tyrosine-protein phosphatase eta-like. (1218 aa)
CD109CD109 antigen. (1322 aa)
PAX6Paired box protein Pax-6. (221 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
PRKAR2AcAMP-dependent protein kinase type II-alpha regulatory subunit. (391 aa)
CORO1Ccoronin-1C. (303 aa)
MAS1Proto-oncogene Mas isoform X1; Belongs to the G-protein coupled receptor 1 family. (325 aa)
RGS14Regulator of G-protein signaling 14. (85 aa)
WWTR1WW domain-containing transcription regulator protein 1. (144 aa)
INPP5JPhosphatidylinositol 4,5-bisphosphate 5-phosphatase A isoform X1. (1004 aa)
DNAJC3dnaJ homolog subfamily C member 3. (504 aa)
LOC102731771Telomeric repeat-binding factor 2-interacting protein 1-like. (122 aa)
PTPROReceptor-type tyrosine-protein phosphatase O isoform X1. (1216 aa)
HHEXHematopoietically-expressed homeobox protein HHEX. (270 aa)
HSPB1Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (207 aa)
PPP4CSerine/threonine-protein phosphatase. (307 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
ADARDouble-stranded RNA-specific adenosine deaminase. (1145 aa)
GBAGlucosylceramidase. (536 aa)
TNFAIP3Tumor necrosis factor alpha-induced protein 3. (790 aa)
LOC102750518Tribbles homolog 3-like. (215 aa)
LOC102736765Interleukin-1 receptor-associated kinase 3-like. (125 aa)
CAMK2N2Calcium/calmodulin-dependent protein kinase II inhibitor 2. (79 aa)
LOC1027361463-phosphoinositide-dependent protein kinase 1-like. (216 aa)
LOC102735151Bone morphogenetic protein 7-like. (139 aa)
LOC102748833Tyrosine-protein kinase. (375 aa)
CDKN1ACyclin-dependent kinase inhibitor 1 isoform X1. (161 aa)
AKT1S1Proline-rich AKT1 substrate 1. (276 aa)
LOC102738369Merlin-like. (110 aa)
VPS25Vacuolar protein-sorting-associated protein 25. (176 aa)
DBNDD1Dysbindin domain-containing protein 1. (158 aa)
BMP2Bone morphogenetic protein 2-like. (395 aa)
AGTAngiotensinogen; Belongs to the serpin family. (477 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
Server load: low (28%) [HD]