STRINGSTRING
IL10 IL10 HTR2B HTR2B CDH13 CDH13 ITGB3 ITGB3 PDCL3 PDCL3 SYNJ2BP SYNJ2BP BMPR2 BMPR2 AGGF1 AGGF1 FGF7 FGF7 PDCD10 PDCD10 VIP VIP ZNF580 ZNF580 NRARP NRARP ATOH8 ATOH8 AKT1 AKT1 TNF TNF LOC102745161 LOC102745161 AIMP1 AIMP1 SIRT6 SIRT6 GHRL GHRL VASH1 VASH1 JUN JUN VEGFC VEGFC AKT3 AKT3 ITGA4 ITGA4 EGR3 EGR3 LECT1 LECT1 LOC102739213 LOC102739213 SP1 SP1 FGFBP1 FGFBP1 VASH2 VASH2 THBS1 THBS1 DLL4 DLL4 PDCD6 PDCD6 ACVRL1 ACVRL1 TNMD TNMD ALDH1A2 ALDH1A2 MEF2C MEF2C EGFL7 EGFL7 BMP6 BMP6 LRG1 LRG1 LOC102736811 LOC102736811 PIK3CD PIK3CD PGF PGF LOC102737831 LOC102737831 DBH DBH VEGFB VEGFB PDGFB PDGFB LOC102735329 LOC102735329 FUT1 FUT1 LEP LEP MMRN2 MMRN2 SCG2 SCG2 LOC102749531 LOC102749531 EMC10 EMC10 LOC102740547 LOC102740547 KIAA1462 KIAA1462 LOC102741947 LOC102741947 LOC102740057 LOC102740057 NF1 NF1 FGF2 FGF2 LOC102736544 LOC102736544 BMP2 BMP2 STAT5A STAT5A STAT3 STAT3 TIE1 TIE1 LOC102736146 LOC102736146 LOC102732559 LOC102732559 LOC102730129 LOC102730129 LOC102736354 LOC102736354 ALOX5 ALOX5 NRAS NRAS ECM1 ECM1 CAV2 CAV2 CAV1 CAV1 APOH APOH FGF10 FGF10 RNASE4 RNASE4 SULF1 SULF1 LOC102743690 LOC102743690 PROK1 PROK1 CCL24 CCL24 CCL26 CCL26
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL10Interleukin-10. (178 aa)
HTR2B5-hydroxytryptamine receptor 2B. (526 aa)
CDH13Cadherin-13-like. (512 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (852 aa)
PDCL3Phosducin-like protein 3. (239 aa)
SYNJ2BPSynaptojanin-2-binding protein. (145 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (974 aa)
AGGF1Angiogenic factor with G patch and FHA domains 1-like. (716 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
PDCD10Programmed cell death protein 10 isoform X1. (212 aa)
VIPVIP peptides isoform X1. (170 aa)
ZNF580Zinc finger protein 580. (172 aa)
NRARPNotch-regulated ankyrin repeat-containing protein. (114 aa)
ATOH8Protein atonal homolog 8. (318 aa)
AKT1Non-specific serine/threonine protein kinase. (518 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
LOC102745161Signal transducer and activator of transcription 3-like. (301 aa)
AIMP1Aminoacyl tRNA synthase complex-interacting multifunctional protein 1. (310 aa)
SIRT6NAD-dependent protein deacetylase sirtuin-6. (359 aa)
GHRLAppetite-regulating hormone isoform X1. (117 aa)
VASH1Vasohibin-1. (363 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (335 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (418 aa)
ITGA4Integrin alpha-4; Belongs to the integrin alpha chain family. (1033 aa)
EGR3Early growth response protein 3 isoform X1. (387 aa)
LECT1Leukocyte cell-derived chemotaxin 1. (360 aa)
LOC102739213High mobility group protein B1-like. (214 aa)
SP1Transcription factor Sp1 isoform X1. (786 aa)
FGFBP1Fibroblast growth factor-binding protein 1. (255 aa)
VASH2Vasohibin-2 isoform X1. (355 aa)
THBS1Thrombospondin-1 isoform X1. (1170 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
PDCD6Programmed cell death protein 6 isoform X1. (189 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
TNMDTenomodulin. (217 aa)
ALDH1A2Retinal dehydrogenase 2 isoform X1; Belongs to the aldehyde dehydrogenase family. (518 aa)
MEF2CMyocyte-specific enhancer factor 2C-like isoform X2. (473 aa)
EGFL7Epidermal growth factor-like protein 7. (274 aa)
BMP6Bone morphogenetic protein 6. (189 aa)
LRG1Leucine-rich alpha-2-glycoprotein. (354 aa)
LOC102736811UPF0556 protein C19orf10 homolog. (173 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
PGFPlacenta growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa)
LOC102737831Serine/threonine-protein kinase D2-like. (246 aa)
DBHDopamine beta-hydroxylase. (274 aa)
VEGFBVascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family. (207 aa)
PDGFBPlatelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (241 aa)
LOC102735329Vascular endothelial growth factor receptor 1-like. (351 aa)
FUT1L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (408 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (166 aa)
MMRN2Multimerin-2-like. (799 aa)
SCG2Secretogranin-2. (618 aa)
LOC102749531Growth/differentiation factor 2-like. (260 aa)
EMC10ER membrane protein complex subunit 10 isoform X1. (262 aa)
LOC102740547Bone morphogenetic protein 4-like isoform X1. (409 aa)
KIAA1462Junctional protein associated with coronary artery disease-like. (1360 aa)
LOC102741947Tenomodulin-like. (164 aa)
LOC102740057Vascular endothelial growth factor A-like isoform X1; Belongs to the PDGF/VEGF growth factor family. (186 aa)
NF1Neurofibromin-like. (1269 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (113 aa)
LOC102736544Thrombospondin-4-like. (685 aa)
BMP2Bone morphogenetic protein 2-like. (395 aa)
STAT5ASignal transducer and activator of transcription 5A. (464 aa)
STAT3Signal transducer and activator of transcription 3-like. (424 aa)
TIE1Tyrosine-protein kinase receptor Tie-1. (1015 aa)
LOC1027361463-phosphoinositide-dependent protein kinase 1-like. (216 aa)
LOC102732559Apelin receptor-like; Belongs to the G-protein coupled receptor 1 family. (380 aa)
LOC102730129Uncharacterized protein LOC102730129. (471 aa)
LOC102736354ATP synthase subunit alpha, mitochondrial-like. (189 aa)
ALOX5Arachidonate 5-lipoxygenase isoform X1. (674 aa)
NRASGTPase NRas. (189 aa)
ECM1LOW QUALITY PROTEIN: extracellular matrix protein 1. (550 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
APOHBeta-2-glycoprotein 1. (345 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa)
RNASE4Ribonuclease 4 isoform X1; Belongs to the pancreatic ribonuclease family. (147 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (867 aa)
LOC102743690Aminoacyl tRNA synthase complex-interacting multifunctional protein 1-like. (319 aa)
PROK1Prokineticin-1. (105 aa)
CCL24c-C motif chemokine 24. (119 aa)
CCL26C-C motif chemokine. (94 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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