(21 nodes) Endochondral ossification network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BMP6	Bone morphogenetic protein 6. (189 aa)
	FGF18	Fibroblast growth factor 18. (116 aa)
	MEF2C	Myocyte-specific enhancer factor 2C-like isoform X2. (473 aa)
	ALPL	Alkaline phosphatase. (469 aa)
	IFT80	Intraflagellar transport protein 80 homolog. (777 aa)
	PHOSPHO1	Phosphoethanolamine/phosphocholine phosphatase. (267 aa)
	MMP14	Matrix metalloproteinase-14. (582 aa)
	MMP13	Collagenase 3. (470 aa)
	LOC102741200	Exostosin-1-like; Belongs to the glycosyltransferase 47 family. (746 aa)
	LOC102747185	Homeobox protein DLX-5-like. (214 aa)
	PHOSPHO2	Pyridoxal phosphate phosphatase PHOSPHO2 isoform X2. (241 aa)
	MMP16	Matrix metalloproteinase-16. (613 aa)
	CSGALNACT1	Hexosyltransferase. (530 aa)
	SMPD3	Sphingomyelin phosphodiesterase 3 isoform X1. (653 aa)
	COL2A1	Collagen alpha-1(II) chain isoform X1. (1487 aa)
	TMEM119	Transmembrane protein 119. (279 aa)
	CBS	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (572 aa)
	LOC102740547	Bone morphogenetic protein 4-like isoform X1. (409 aa)
	LOC102734562	Inositol monophosphatase 3-like. (171 aa)
	NAB2	NGFI-A-binding protein 2. (525 aa)
	PEX7	Peroxisomal targeting signal 2 receptor. (354 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALPL	COL2A1	A0A2U3YLB1	A0A2U3XCY5	Alkaline phosphatase.	Collagen alpha-1(II) chain isoform X1.	0.545
ALPL	LOC102747185	A0A2U3YLB1	A0A2U3XXX5	Alkaline phosphatase.	Homeobox protein DLX-5-like.	0.469
BMP6	LOC102740547	A0A2U3YPC2	A0A2U3Z034	Bone morphogenetic protein 6.	Bone morphogenetic protein 4-like isoform X1.	0.944
COL2A1	ALPL	A0A2U3XCY5	A0A2U3YLB1	Collagen alpha-1(II) chain isoform X1.	Alkaline phosphatase.	0.545
COL2A1	LOC102740547	A0A2U3XCY5	A0A2U3Z034	Collagen alpha-1(II) chain isoform X1.	Bone morphogenetic protein 4-like isoform X1.	0.434
COL2A1	MMP13	A0A2U3XCY5	A0A2U3YCN5	Collagen alpha-1(II) chain isoform X1.	Collagenase 3.	0.823
CSGALNACT1	LOC102741200	A0A2U3XQ92	A0A2U3Y7L0	Hexosyltransferase.	Exostosin-1-like; Belongs to the glycosyltransferase 47 family.	0.478
FGF18	LOC102740547	A0A2U3YP56	A0A2U3Z034	Fibroblast growth factor 18.	Bone morphogenetic protein 4-like isoform X1.	0.652
LOC102740547	BMP6	A0A2U3Z034	A0A2U3YPC2	Bone morphogenetic protein 4-like isoform X1.	Bone morphogenetic protein 6.	0.944
LOC102740547	COL2A1	A0A2U3Z034	A0A2U3XCY5	Bone morphogenetic protein 4-like isoform X1.	Collagen alpha-1(II) chain isoform X1.	0.434
LOC102740547	FGF18	A0A2U3Z034	A0A2U3YP56	Bone morphogenetic protein 4-like isoform X1.	Fibroblast growth factor 18.	0.652
LOC102740547	LOC102747185	A0A2U3Z034	A0A2U3XXX5	Bone morphogenetic protein 4-like isoform X1.	Homeobox protein DLX-5-like.	0.611
LOC102740547	MEF2C	A0A2U3Z034	A0A2U3YMC3	Bone morphogenetic protein 4-like isoform X1.	Myocyte-specific enhancer factor 2C-like isoform X2.	0.400
LOC102741200	CSGALNACT1	A0A2U3Y7L0	A0A2U3XQ92	Exostosin-1-like; Belongs to the glycosyltransferase 47 family.	Hexosyltransferase.	0.478
LOC102747185	ALPL	A0A2U3XXX5	A0A2U3YLB1	Homeobox protein DLX-5-like.	Alkaline phosphatase.	0.469
LOC102747185	LOC102740547	A0A2U3XXX5	A0A2U3Z034	Homeobox protein DLX-5-like.	Bone morphogenetic protein 4-like isoform X1.	0.611
MEF2C	LOC102740547	A0A2U3YMC3	A0A2U3Z034	Myocyte-specific enhancer factor 2C-like isoform X2.	Bone morphogenetic protein 4-like isoform X1.	0.400
MMP13	COL2A1	A0A2U3YCN5	A0A2U3XCY5	Collagenase 3.	Collagen alpha-1(II) chain isoform X1.	0.823
MMP13	MMP14	A0A2U3YCN5	A0A2U3YSI0	Collagenase 3.	Matrix metalloproteinase-14.	0.932
MMP13	MMP16	A0A2U3YCN5	A0A2U3XQW6	Collagenase 3.	Matrix metalloproteinase-16.	0.926