STRINGSTRING
SEMA3C SEMA3C SEC24B SEC24B NPY2R NPY2R SFRP2 SFRP2 NOG NOG GJA5 GJA5 NIPBL NIPBL FGF8 FGF8 ILK ILK GATA6 GATA6 TBX20 TBX20 BMPR2 BMPR2 SMAD4 SMAD4 FZD2 FZD2 JAG1 JAG1 NKX2-5 NKX2-5 HIF1A HIF1A DVL2 DVL2 TBX3 TBX3 JUN JUN BMPR1A BMPR1A ATF2 ATF2 SOX17 SOX17 WNT11 WNT11 EYA1 EYA1 CRKL CRKL MEF2C MEF2C FOXH1 FOXH1 LOC102729478 LOC102729478 NPY1R NPY1R LOC102741543 LOC102741543 CITED2 CITED2 LOC102740547 LOC102740547 LOC102750017 LOC102750017 LOC102727186 LOC102727186 LOC102745028 LOC102745028
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SEMA3Csemaphorin-3C; Belongs to the semaphorin family. (696 aa)
SEC24BProtein transport protein Sec24B isoform X1. (1258 aa)
NPY2RNeuropeptide Y receptor type 2; Belongs to the G-protein coupled receptor 1 family. (382 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
NIPBLNipped-B protein. (2803 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (140 aa)
ILKIntegrin-linked protein kinase isoform X1. (452 aa)
GATA6Transcription factor GATA-6. (287 aa)
TBX20T-box transcription factor TBX20. (447 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (974 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
FZD2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
NKX2-5Homeobox protein Nkx-2.5. (323 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X1. (823 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2 isoform X1. (734 aa)
TBX3T-box transcription factor TBX3. (675 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (335 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X2. (505 aa)
SOX17Transcription factor SOX-17-like. (406 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
CRKLCrk-like protein. (303 aa)
MEF2CMyocyte-specific enhancer factor 2C-like isoform X2. (473 aa)
FOXH1Forkhead box protein H1. (360 aa)
LOC102729478Endothelin-1 receptor-like; Belongs to the G-protein coupled receptor 1 family. (253 aa)
NPY1RNeuropeptide Y receptor type 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
LOC102741543Zinc finger protein ZFPM2-like. (827 aa)
CITED2Cbp/p300-interacting transactivator 2. (271 aa)
LOC102740547Bone morphogenetic protein 4-like isoform X1. (409 aa)
LOC102750017Mothers against decapentaplegic homolog 6-like. (181 aa)
LOC102727186Heart- and neural crest derivatives-expressed protein 2-like. (217 aa)
LOC102745028Endothelin-1 receptor-like. (178 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.