STRINGSTRING
LOC102730020 LOC102730020 WNT11 WNT11 LOC102728858 LOC102728858 HAND1 HAND1 FOXF1 FOXF1 MEF2C MEF2C FOXH1 FOXH1 LOC102729478 LOC102729478 MED1 MED1 LOC102741543 LOC102741543 CITED2 CITED2 LOC102748022 LOC102748022 LOC102740547 LOC102740547 LOC102726090 LOC102726090 SEMA3C SEMA3C CPE CPE NPY2R NPY2R SFRP2 SFRP2 CHD7 CHD7 NOG NOG GJA5 GJA5 DCTN5 DCTN5 LOC102731945 LOC102731945 SAV1 SAV1 TNNC1 TNNC1 LOC102725595 LOC102725595 SALL4 SALL4 TBX20 TBX20 CYR61 CYR61 BMPR2 BMPR2 SMAD4 SMAD4 FZD2 FZD2 LOC102726900 LOC102726900 PTK7 PTK7 JAG1 JAG1 MYL2 MYL2 ZMPSTE24 ZMPSTE24 NKX2-5 NKX2-5 PPP1R13L PPP1R13L HIF1A HIF1A PRDM1 PRDM1 TBX3 TBX3 MDM2 MDM2 BMPR1A BMPR1A GATA3 GATA3 DLL4 DLL4 LOC102746898 LOC102746898 SMARCD3 SMARCD3 LOC102750017 LOC102750017 GSK3A GSK3A LOC102742062 LOC102742062 LOC102727186 LOC102727186 LOC102732559 LOC102732559 LOC102745028 LOC102745028
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102730020Myosin-7-like. (703 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
LOC102728858Fibroblast growth factor receptor substrate 2-like; Belongs to the TCP-1 chaperonin family. (251 aa)
HAND1Heart- and neural crest derivatives-expressed protein 1. (218 aa)
FOXF1Forkhead box protein F1. (427 aa)
MEF2CMyocyte-specific enhancer factor 2C-like isoform X2. (473 aa)
FOXH1Forkhead box protein H1. (360 aa)
LOC102729478Endothelin-1 receptor-like; Belongs to the G-protein coupled receptor 1 family. (253 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1582 aa)
LOC102741543Zinc finger protein ZFPM2-like. (827 aa)
CITED2Cbp/p300-interacting transactivator 2. (271 aa)
LOC102748022Xin actin-binding repeat-containing protein 2-like. (3244 aa)
LOC102740547Bone morphogenetic protein 4-like isoform X1. (409 aa)
LOC102726090Matrin-3-like. (157 aa)
SEMA3Csemaphorin-3C; Belongs to the semaphorin family. (696 aa)
CPECarboxypeptidase E. (440 aa)
NPY2RNeuropeptide Y receptor type 2; Belongs to the G-protein coupled receptor 1 family. (382 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
CHD7chromodomain-helicase-DNA-binding protein 7. (2429 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
DCTN5Dynactin subunit 5. (182 aa)
LOC102731945Suppressor of fused homolog. (106 aa)
SAV1Protein salvador homolog 1. (384 aa)
TNNC1Troponin C, slow skeletal and cardiac muscles. (161 aa)
LOC102725595Fibroblast growth factor receptor substrate 2-like. (316 aa)
SALL4Sal-like protein 4. (1052 aa)
TBX20T-box transcription factor TBX20. (447 aa)
CYR61Protein CYR61. (382 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (974 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
FZD2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
LOC102726900Mothers against decapentaplegic homolog 7-like. (178 aa)
PTK7Inactive tyrosine-protein kinase 7 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
MYL2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform isoform X1. (166 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
NKX2-5Homeobox protein Nkx-2.5. (323 aa)
PPP1R13LrelA-associated inhibitor. (827 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X1. (823 aa)
PRDM1PR domain zinc finger protein 1 isoform X3. (818 aa)
TBX3T-box transcription factor TBX3. (675 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (487 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
LOC102746898Protein GREB1-like. (1593 aa)
SMARCD3SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3. (435 aa)
LOC102750017Mothers against decapentaplegic homolog 6-like. (181 aa)
GSK3AGlycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (419 aa)
LOC102742062T-box transcription factor TBX5-like. (308 aa)
LOC102727186Heart- and neural crest derivatives-expressed protein 2-like. (217 aa)
LOC102732559Apelin receptor-like; Belongs to the G-protein coupled receptor 1 family. (380 aa)
LOC102745028Endothelin-1 receptor-like. (178 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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