STRINGSTRING
FOXA3 FOXA3 EHF EHF LOC102727091 LOC102727091 LOC102751021 LOC102751021 LOC102750521 LOC102750521 LOC102741471 LOC102741471 LOC102731864 LOC102731864 WNT10B WNT10B TFAP2D TFAP2D LOC102733867 LOC102733867 LOC102745331 LOC102745331 LOC102747355 LOC102747355 MYOD1 MYOD1 LOC102732446 LOC102732446 STAT3 STAT3 LOC102742062 LOC102742062 BMP2 BMP2 FGF2 FGF2 LOC102729615 LOC102729615 LOC102749540 LOC102749540 LOC102746660 LOC102746660 LOC102733739 LOC102733739 CCDC124 CCDC124 LOC102740547 LOC102740547 BCL9L BCL9L LOC102749531 LOC102749531 PCF11 PCF11 GSX1 GSX1 POLR2C POLR2C RXRA RXRA CIC CIC SOX10 SOX10 INHBA INHBA HFE2 HFE2 LOC102736516 LOC102736516 ERCC3 ERCC3 CD28 CD28 TBPL1 TBPL1 MED1 MED1 GTF2H1 GTF2H1 PRDM4 PRDM4 LOC102725943 LOC102725943 FOS FOS LOC102742531 LOC102742531 PTH PTH RBMX RBMX LOC102727345 LOC102727345 LOC102738225 LOC102738225 GRHL3 GRHL3 GTF2A1L GTF2A1L LOC102728667 LOC102728667 TBP TBP ADRM1 ADRM1 TAF4 TAF4 ELOF1 ELOF1 SMAD1 SMAD1 GTF2I GTF2I MSX1 MSX1 SUPT5H SUPT5H PAF1 PAF1 FOXP3 FOXP3 LOC102730890 LOC102730890 ATXN1L ATXN1L TCEA1 TCEA1 ATF2 ATF2 TAF13 TAF13 ZIC3 ZIC3 PAXBP1 PAXBP1 POLR2L POLR2L HSF4 HSF4 POLR2D POLR2D TAF3 TAF3 GATA3 GATA3 LOC102744859 LOC102744859 NKX2-8 NKX2-8 POLR2E POLR2E MED4 MED4 RB1 RB1 EPAS1 EPAS1 GTF2H3 GTF2H3 SCAF8 SCAF8 CYTL1 CYTL1 LOC102731796 LOC102731796 TAF12 TAF12 MED18 MED18 GCM2 GCM2 ELF3 ELF3 HOXD13 HOXD13 GTF2H5 GTF2H5 POLR2A POLR2A GTF2H2 GTF2H2 TAF9 TAF9 SNAPC3 SNAPC3 TFDP1 TFDP1 ERCC2 ERCC2 ZBTB1 ZBTB1 STAT5B STAT5B LOC102745161 LOC102745161 GTF2B GTF2B SNAPC1 SNAPC1 GATA1 GATA1 POLR2H POLR2H IL2 IL2 ZNF768 ZNF768 TNFRSF1A TNFRSF1A TCEA3 TCEA3 SUB1 SUB1 ZC3H8 ZC3H8 BCL6 BCL6 TAF11 TAF11 SPDEF SPDEF SRF SRF TBPL2 TBPL2 ETV7 ETV7 GTF2F2 GTF2F2 TFCP2 TFCP2 HELT HELT ASH1L ASH1L SMAD4 SMAD4 IRF1 IRF1 LOC102733670 LOC102733670 HNF4A HNF4A SUPT3H SUPT3H NMI NMI SNAPC2 SNAPC2 TAF6 TAF6 NKX2-3 NKX2-3 ATOH1 ATOH1 LEO1 LEO1 CREB1 CREB1 NFIL3 NFIL3 LHX1 LHX1 GTF2E1 GTF2E1 CEBPB CEBPB ABRA ABRA GTF2E2 GTF2E2 SUPT6H SUPT6H TAF7 TAF7 POLR2I POLR2I SUPT16H SUPT16H NR4A2 NR4A2 LOC102732851 LOC102732851 LOC102726171 LOC102726171 POLR2B POLR2B LOC102726679 LOC102726679 POLR2G POLR2G NR1H3 NR1H3 NFAT5 NFAT5 EP300 EP300 MNAT1 MNAT1 ATF4 ATF4 PTF1A PTF1A CHD7 CHD7 VDR VDR PAX6 PAX6 DDX21 DDX21 DR1 DR1 CTR9 CTR9 CDC73 CDC73 S100A10 S100A10 CCNH CCNH LEF1 LEF1 TAF9B TAF9B ATRX ATRX
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FOXA3Hepatocyte nuclear factor 3-gamma. (350 aa)
EHFLOW QUALITY PROTEIN: ets homologous factor. (228 aa)
LOC102727091Transcription elongation factor A protein 3-like. (103 aa)
LOC102751021Phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1. (454 aa)
LOC102750521NMDA receptor-regulated protein 2-like. (239 aa)
LOC102741471Parafibromin-like. (141 aa)
LOC102731864Signal transducer and activator of transcription 5B-like. (353 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
TFAP2DTranscription factor AP-2-delta-like. (294 aa)
LOC102733867Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (235 aa)
LOC102745331Transcription initiation factor TFIID subunit 8-like. (269 aa)
LOC102747355Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (268 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
LOC102732446ETS homologous factor-like. (118 aa)
STAT3Signal transducer and activator of transcription 3-like. (424 aa)
LOC102742062T-box transcription factor TBX5-like. (308 aa)
BMP2Bone morphogenetic protein 2-like. (395 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (113 aa)
LOC102729615RNA polymerase II subunit A C-terminal domain phosphatase SSU72-like isoform X2. (194 aa)
LOC102749540Protein capicua homolog. (1444 aa)
LOC102746660RNA polymerase-associated protein CTR9 homolog. (452 aa)
LOC102733739DNA-directed RNA polymerase II subunit RPB3-like. (189 aa)
CCDC124Coiled-coil domain-containing protein 124 isoform X1. (223 aa)
LOC102740547Bone morphogenetic protein 4-like isoform X1. (409 aa)
BCL9LB-cell CLL/lymphoma 9-like protein isoform X1. (1495 aa)
LOC102749531Growth/differentiation factor 2-like. (260 aa)
PCF11pre-mRNA cleavage complex 2 protein Pcf11. (1555 aa)
GSX1GS homeobox 1. (347 aa)
POLR2CDNA-directed RNA polymerase II subunit RPB3. (98 aa)
RXRARetinoic acid receptor RXR-alpha. (439 aa)
CICProtein capicua homolog. (134 aa)
SOX10Transcription factor SOX-10. (469 aa)
INHBAInhibin beta A chain. (424 aa)
HFE2Hemojuvelin-like isoform X1. (428 aa)
LOC102736516Phosphatidylinositol 3-kinase regulatory subunit alpha-like. (138 aa)
ERCC3TFIIH basal transcription factor complex helicase XPB subunit. (782 aa)
CD28T-cell-specific surface glycoprotein CD28. (209 aa)
TBPL1TATA box-binding protein-like protein 1. (186 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1582 aa)
GTF2H1General transcription factor IIH subunit 1. (441 aa)
PRDM4PR domain zinc finger protein 4; May function as a transcription factor involved in cell differentiation. (801 aa)
LOC102725943Nuclear factor of activated T-cells, cytoplasmic 2-like. (160 aa)
FOSProto-oncogene c-Fos isoform X1. (380 aa)
LOC102742531RNA-binding motif protein, X chromosome-like. (314 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
RBMXRNA binding motif protein, X-linked-like-1 isoform X1. (391 aa)
LOC102727345Transcription factor SOX-9-like. (282 aa)
LOC102738225Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (117 aa)
GRHL3Grainyhead-like protein 3 homolog. (602 aa)
GTF2A1LTFIIA-alpha and beta-like factor isoform X1. (477 aa)
LOC102728667Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (101 aa)
TBPTATA-box-binding protein. (322 aa)
ADRM1Proteasomal ubiquitin receptor ADRM1 isoform X1. (406 aa)
TAF4Transcription initiation factor TFIID subunit 4. (668 aa)
ELOF1Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (83 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
GTF2IGeneral transcription factor II-I. (992 aa)
MSX1Homeobox protein MSX-1. (303 aa)
SUPT5HTranscription elongation factor SPT5. (1087 aa)
PAF1RNA polymerase II-associated factor 1 homolog isoform X2. (528 aa)
FOXP3Forkhead box protein P3 isoform X1. (456 aa)
LOC102730890NEDD4-like E3 ubiquitin-protein ligase WWP2-like. (205 aa)
ATXN1LAtaxin-1-like isoform X1. (688 aa)
TCEA1Transcription elongation factor A protein 1 isoform X1. (301 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X2. (505 aa)
TAF13Transcription initiation factor TFIID subunit 13. (124 aa)
ZIC3Zinc finger protein ZIC 3. (465 aa)
PAXBP1PAX3- and PAX7-binding protein 1. (918 aa)
POLR2LDNA-directed RNA polymerases I, II, and III subunit RPABC5. (67 aa)
HSF4Heat shock factor protein 4 isoform X1. (493 aa)
POLR2DDNA-directed RNA polymerase II subunit RPB4. (142 aa)
TAF3Transcription initiation factor TFIID subunit 3. (774 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
LOC102744859SWI/SNF complex subunit SMARCC2-like. (344 aa)
NKX2-8Homeobox protein Nkx-2.8. (239 aa)
POLR2EDNA-directed RNA polymerases I, II, and III subunit RPABC1 isoform X1. (210 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (270 aa)
RB1Retinoblastoma-associated protein. (846 aa)
EPAS1Endothelial PAS domain-containing protein 1. (865 aa)
GTF2H3General transcription factor IIH subunit 3. (162 aa)
SCAF8Protein SCAF8 isoform X1. (1354 aa)
CYTL1Cytokine-like protein 1. (133 aa)
LOC102731796Dr1-associated corepressor-like isoform X1. (212 aa)
TAF12Transcription initiation factor TFIID subunit 12 isoform X1. (161 aa)
MED18Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (208 aa)
GCM2Chorion-specific transcription factor GCMb. (506 aa)
ELF3ETS-related transcription factor Elf-3. (369 aa)
HOXD13Homeobox protein Hox-D13. (204 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa)
GTF2H2General transcription factor IIH subunit. (395 aa)
TAF9Transcription initiation factor TFIID subunit 9-like isoform X1. (265 aa)
SNAPC3snRNA-activating protein complex subunit 3. (412 aa)
TFDP1Transcription factor. (290 aa)
ERCC2TFIIH basal transcription factor complex helicase XPD subunit. (661 aa)
ZBTB1Zinc finger and BTB domain-containing protein 1 isoform X1. (713 aa)
STAT5BSignal transducer and activator of transcription 5B. (508 aa)
LOC102745161Signal transducer and activator of transcription 3-like. (301 aa)
GTF2BTranscription initiation factor IIB. (316 aa)
SNAPC1snRNA-activating protein complex subunit 1. (378 aa)
GATA1Erythroid transcription factor. (413 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X1. (114 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
ZNF768Zinc finger protein 768. (552 aa)
TNFRSF1ATumor necrosis factor receptor superfamily member 1A. (358 aa)
TCEA3Transcription elongation factor A protein 3. (74 aa)
SUB1Activated RNA polymerase II transcriptional coactivator p15 isoform X1. (126 aa)
ZC3H8Zinc finger CCCH domain-containing protein 8. (305 aa)
BCL6B-cell lymphoma 6 protein. (706 aa)
TAF11Transcription initiation factor TFIID subunit 11 isoform X1. (211 aa)
SPDEFSAM pointed domain-containing Ets transcription factor. (335 aa)
SRFSerum response factor. (508 aa)
TBPL2TATA box-binding protein-like protein 2. (344 aa)
ETV7Transcription factor ETV7 isoform X1. (255 aa)
GTF2F2General transcription factor IIF subunit 2. (239 aa)
TFCP2Alpha-globin transcription factor CP2 isoform X2. (504 aa)
HELTHairy and enhancer of split-related protein HELT isoform X1. (242 aa)
ASH1LHistone-lysine N-methyltransferase ASH1L. (2965 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
IRF1Interferon regulatory factor. (322 aa)
LOC102733670Probable helicase senataxin-like. (227 aa)
HNF4AHepatocyte nuclear factor 4-alpha. (399 aa)
SUPT3HTranscription initiation protein SPT3 homolog. (377 aa)
NMIN-myc-interactor. (314 aa)
SNAPC2snRNA-activating protein complex subunit 2. (331 aa)
TAF6Transcription initiation factor TFIID subunit 6 isoform X1. (677 aa)
NKX2-3Homeobox protein Nkx-2.3. (307 aa)
ATOH1Protein atonal homolog 1. (355 aa)
LEO1RNA polymerase-associated protein LEO1. (570 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
NFIL3Nuclear factor interleukin-3-regulated protein. (462 aa)
LHX1LIM/homeobox protein Lhx1. (406 aa)
GTF2E1General transcription factor IIE subunit 1. (438 aa)
CEBPBCCAAT/enhancer-binding protein. (345 aa)
ABRAActin-binding Rho-activating protein. (380 aa)
GTF2E2Transcription initiation factor IIE subunit beta. (240 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa)
TAF7Transcription initiation factor TFIID subunit 7. (349 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
SUPT16HFACT complex subunit SPT16. (1047 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2 isoform X2. (598 aa)
LOC102732851LIM domain-binding protein 1-like. (227 aa)
LOC102726171LIM domain-binding protein 1-like. (190 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
LOC102726679Protein S100-A10-like; Belongs to the S-100 family. (97 aa)
POLR2GDNA-directed RNA polymerase II subunit RPB7. (172 aa)
NR1H3Oxysterols receptor LXR-alpha isoform X1. (456 aa)
NFAT5Nuclear factor of activated T-cells 5 isoform X1. (1545 aa)
EP300Histone acetyltransferase p300. (2425 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
PTF1APancreas transcription factor 1 subunit alpha. (156 aa)
CHD7chromodomain-helicase-DNA-binding protein 7. (2429 aa)
VDRVitamin D3 receptor. (427 aa)
PAX6Paired box protein Pax-6. (221 aa)
DDX21Nucleolar RNA helicase 2 isoform X1. (795 aa)
DR1Protein Dr1 isoform X1. (175 aa)
CTR9RNA polymerase-associated protein CTR9 homolog. (723 aa)
CDC73Parafibromin. (418 aa)
S100A10Protein S100-A10; Belongs to the S-100 family. (97 aa)
CCNHcyclin-H-like; Belongs to the cyclin family. (344 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (399 aa)
TAF9BTranscription initiation factor TFIID subunit 9B. (250 aa)
ATRXTranscriptional regulator ATRX isoform X1. (2489 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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