(56 nodes) Positive regulation of endothelial cell migration network (Leptonychotes weddellii)

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	LOC102739213	High mobility group protein B1-like. (214 aa)
	LOC102726881	Breast cancer anti-estrogen resistance protein 1-like. (695 aa)
	LOC102730129	Uncharacterized protein LOC102730129. (471 aa)
	LOC102736354	ATP synthase subunit alpha, mitochondrial-like. (189 aa)
	LOC102750030	Protein-tyrosine kinase 2-beta-like. (125 aa)
	AGT	Angiotensinogen; Belongs to the serpin family. (477 aa)
	AAMP	Angio-associated migratory cell protein isoform X1. (436 aa)
	LOC102734950	Forkhead box protein P1-like. (351 aa)
	STAT5A	Signal transducer and activator of transcription 5A. (464 aa)
	LOC102744822	Fibroblast growth factor 1; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins [...] (56 aa)
	GATA3	Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
	MAP3K3	Mitogen-activated protein kinase kinase kinase 3. (600 aa)
	ETS1	Protein C-ets-1-like isoform X1. (441 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (418 aa)
	GPLD1	Phosphatidylinositol-glycan-specific phospholipase D. (840 aa)
	HDAC7	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (928 aa)
	HIF1A	Hypoxia-inducible factor 1-alpha isoform X1. (823 aa)
	AKT1	Non-specific serine/threonine protein kinase. (518 aa)
	ATOH8	Protein atonal homolog 8. (318 aa)
	FGF16	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	LOC102739837	Glucose-6-phosphate isomerase; Belongs to the GPI family. (558 aa)
	LOC102726446	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like; Belongs to the PI3/PI4-kinase family. (235 aa)
	HSPB1	Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (207 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (852 aa)
	NUS1	nogo-B receptor-like. (293 aa)
	BMPR2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (974 aa)
	ZNF580	Zinc finger protein 580. (172 aa)
	LOC102738400	Annexin. (345 aa)
	P2RX4	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (388 aa)
	TEK	Angiopoietin-1 receptor isoform X1. (1125 aa)
	ITGB1BP1	Integrin beta-1-binding protein 1 isoform X1. (200 aa)
	GPR124	G-protein coupled receptor 124; Belongs to the G-protein coupled receptor 2 family. (1332 aa)
	SP1	Transcription factor Sp1 isoform X1. (786 aa)
	FGFBP1	Fibroblast growth factor-binding protein 1. (255 aa)
	THBS1	Thrombospondin-1 isoform X1. (1170 aa)
	PDCD6	Programmed cell death protein 6 isoform X1. (189 aa)
	SRPX2	Sushi repeat-containing protein SRPX2. (465 aa)
	RRAS	Ras-related protein R-Ras. (218 aa)
	RHOJ	Rho-related GTP-binding protein RhoJ. (214 aa)
	FGF18	Fibroblast growth factor 18. (116 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
	ANGPT4	Angiopoietin-4. (498 aa)
	LOC102737831	Serine/threonine-protein kinase D2-like. (246 aa)
	LOC102736146	3-phosphoinositide-dependent protein kinase 1-like. (216 aa)
	MAP2K3	Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
	PDGFB	Platelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (241 aa)
	TGFB1	Transforming growth factor beta-1. (261 aa)
	FUT1	L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (408 aa)
	ABL1	Tyrosine-protein kinase ABL1-like. (312 aa)
	EMC10	ER membrane protein complex subunit 10 isoform X1. (262 aa)
	LOC102740547	Bone morphogenetic protein 4-like isoform X1. (409 aa)
	KIAA1462	Junctional protein associated with coronary artery disease-like. (1360 aa)
	SASH1	SAM and SH3 domain-containing protein 1-like. (1070 aa)
	LOC102740057	Vascular endothelial growth factor A-like isoform X1; Belongs to the PDGF/VEGF growth factor family. (186 aa)
	LOC102730108	Neuropilin-1-like. (465 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (113 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAMP	TEK	A0A2U3Z3P2	A0A2U3Y080	Angio-associated migratory cell protein isoform X1.	Angiopoietin-1 receptor isoform X1.	0.481
ABL1	LOC102750030	A0A2U3YZ15	A0A2U3Z8N4	Tyrosine-protein kinase ABL1-like.	Protein-tyrosine kinase 2-beta-like.	0.692
ABL1	RHOJ	A0A2U3YZ15	A0A2U3YNJ6	Tyrosine-protein kinase ABL1-like.	Rho-related GTP-binding protein RhoJ.	0.445
ABL1	STAT5A	A0A2U3YZ15	A0A2U3Z446	Tyrosine-protein kinase ABL1-like.	Signal transducer and activator of transcription 5A.	0.912
AGT	TGFB1	A0A2U3Z3P7	A0A2U3YVA3	Angiotensinogen; Belongs to the serpin family.	Transforming growth factor beta-1.	0.514
AKT1	AKT3	A0A2U3Y3V3	A0A2U3Y8K7	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.808
AKT1	HSPB1	A0A2U3Y3V3	A0A2U3XR88	Non-specific serine/threonine protein kinase.	Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family.	0.452
AKT1	LOC102726446	A0A2U3Y3V3	A0A2U3X957	Non-specific serine/threonine protein kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like; Belongs to the PI3/PI4-kinase family.	0.896
AKT1	LOC102736146	A0A2U3Y3V3	A0A2U3Z6N9	Non-specific serine/threonine protein kinase.	3-phosphoinositide-dependent protein kinase 1-like.	0.955
AKT1	PIK3CD	A0A2U3Y3V3	A0A2U3YPT2	Non-specific serine/threonine protein kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.871
AKT1	TGFB1	A0A2U3Y3V3	A0A2U3YVA3	Non-specific serine/threonine protein kinase.	Transforming growth factor beta-1.	0.462
AKT3	AKT1	A0A2U3Y8K7	A0A2U3Y3V3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.808
AKT3	HSPB1	A0A2U3Y8K7	A0A2U3XR88	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family.	0.452
AKT3	LOC102726446	A0A2U3Y8K7	A0A2U3X957	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like; Belongs to the PI3/PI4-kinase family.	0.944
AKT3	LOC102736146	A0A2U3Y8K7	A0A2U3Z6N9	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	3-phosphoinositide-dependent protein kinase 1-like.	0.974
AKT3	PIK3CD	A0A2U3Y8K7	A0A2U3YPT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.874
AKT3	STAT5A	A0A2U3Y8K7	A0A2U3Z446	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Signal transducer and activator of transcription 5A.	0.438
AKT3	TGFB1	A0A2U3Y8K7	A0A2U3YVA3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Transforming growth factor beta-1.	0.462
ANGPT4	TEK	A0A2U3YQX4	A0A2U3Y080	Angiopoietin-4.	Angiopoietin-1 receptor isoform X1.	0.995
ATOH8	SRPX2	A0A2U3Y2F2	A0A2U3YJU0	Protein atonal homolog 8.	Sushi repeat-containing protein SRPX2.	0.660