(16 nodes) Striated muscle adaptation network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASB2	Ankyrin repeat and SOCS box protein 2. (630 aa)
	MYOD1	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
	LOC102737664	Gelsolin-like. (513 aa)
	LOC102730020	Myosin-7-like. (703 aa)
	LOC102745380	Histone-lysine N-methyltransferase EZH2-like. (556 aa)
	CAMTA2	Calmodulin-binding transcription activator 2 isoform X4. (1196 aa)
	TCAP	Telethonin isoform X2. (167 aa)
	EZH2	Histone-lysine N-methyltransferase EZH2. (144 aa)
	MYOZ1	Myozenin-1 isoform X2. (221 aa)
	MYOG	Myogenin. (224 aa)
	GATA6	Transcription factor GATA-6. (287 aa)
	GSN	Gelsolin. (189 aa)
	MYOC	Myocilin. (490 aa)
	KDM4A	Lysine-specific demethylase 4A. (480 aa)
	MYOZ2	Myozenin-2. (264 aa)
	LOC102746625	Lysine-specific demethylase 4A-like. (404 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EZH2	LOC102745380	A0A2U3XHJ2	A0A2U3YH25	Histone-lysine N-methyltransferase EZH2.	Histone-lysine N-methyltransferase EZH2-like.	0.900
EZH2	MYOG	A0A2U3XHJ2	A0A2U3XJX0	Histone-lysine N-methyltransferase EZH2.	Myogenin.	0.426
KDM4A	LOC102746625	A0A2U3Y8H7	A0A2U3YU59	Lysine-specific demethylase 4A.	Lysine-specific demethylase 4A-like.	0.900
LOC102730020	MYOD1	A0A2U3Z8B7	A0A2U3Z4X5	Myosin-7-like.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.481
LOC102730020	MYOG	A0A2U3Z8B7	A0A2U3XJX0	Myosin-7-like.	Myogenin.	0.672
LOC102730020	MYOZ1	A0A2U3Z8B7	A0A2U3XI86	Myosin-7-like.	Myozenin-1 isoform X2.	0.729
LOC102730020	TCAP	A0A2U3Z8B7	A0A2U3YTG0	Myosin-7-like.	Telethonin isoform X2.	0.481
LOC102745380	EZH2	A0A2U3YH25	A0A2U3XHJ2	Histone-lysine N-methyltransferase EZH2-like.	Histone-lysine N-methyltransferase EZH2.	0.900
LOC102745380	MYOG	A0A2U3YH25	A0A2U3XJX0	Histone-lysine N-methyltransferase EZH2-like.	Myogenin.	0.426
LOC102746625	KDM4A	A0A2U3YU59	A0A2U3Y8H7	Lysine-specific demethylase 4A-like.	Lysine-specific demethylase 4A.	0.900
MYOD1	LOC102730020	A0A2U3Z4X5	A0A2U3Z8B7	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Myosin-7-like.	0.481
MYOD1	MYOG	A0A2U3Z4X5	A0A2U3XJX0	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Myogenin.	0.809
MYOG	EZH2	A0A2U3XJX0	A0A2U3XHJ2	Myogenin.	Histone-lysine N-methyltransferase EZH2.	0.426
MYOG	LOC102730020	A0A2U3XJX0	A0A2U3Z8B7	Myogenin.	Myosin-7-like.	0.672
MYOG	LOC102745380	A0A2U3XJX0	A0A2U3YH25	Myogenin.	Histone-lysine N-methyltransferase EZH2-like.	0.426
MYOG	MYOD1	A0A2U3XJX0	A0A2U3Z4X5	Myogenin.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.809
MYOZ1	LOC102730020	A0A2U3XI86	A0A2U3Z8B7	Myozenin-1 isoform X2.	Myosin-7-like.	0.729
MYOZ1	TCAP	A0A2U3XI86	A0A2U3YTG0	Myozenin-1 isoform X2.	Telethonin isoform X2.	0.661
MYOZ2	TCAP	A0A2U3YAC3	A0A2U3YTG0	Myozenin-2.	Telethonin isoform X2.	0.586
TCAP	LOC102730020	A0A2U3YTG0	A0A2U3Z8B7	Telethonin isoform X2.	Myosin-7-like.	0.481