(12 nodes) Muscle hypertrophy network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MYOC	Myocilin. (490 aa)
	HTR2B	5-hydroxytryptamine receptor 2B. (526 aa)
	GATA6	Transcription factor GATA-6. (287 aa)
	IGF1	Insulin-like growth factor I isoform X1. (153 aa)
	EZH2	Histone-lysine N-methyltransferase EZH2. (144 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	KDM4A	Lysine-specific demethylase 4A. (480 aa)
	LOC102745380	Histone-lysine N-methyltransferase EZH2-like. (556 aa)
	CAMTA2	Calmodulin-binding transcription activator 2 isoform X4. (1196 aa)
	TCAP	Telethonin isoform X2. (167 aa)
	LOC102746625	Lysine-specific demethylase 4A-like. (404 aa)
	LOC102730020	Myosin-7-like. (703 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EZH2	LOC102745380	A0A2U3XHJ2	A0A2U3YH25	Histone-lysine N-methyltransferase EZH2.	Histone-lysine N-methyltransferase EZH2-like.	0.900
KDM4A	LOC102746625	A0A2U3Y8H7	A0A2U3YU59	Lysine-specific demethylase 4A.	Lysine-specific demethylase 4A-like.	0.900
LOC102730020	TCAP	A0A2U3Z8B7	A0A2U3YTG0	Myosin-7-like.	Telethonin isoform X2.	0.481
LOC102745380	EZH2	A0A2U3YH25	A0A2U3XHJ2	Histone-lysine N-methyltransferase EZH2-like.	Histone-lysine N-methyltransferase EZH2.	0.900
LOC102746625	KDM4A	A0A2U3YU59	A0A2U3Y8H7	Lysine-specific demethylase 4A-like.	Lysine-specific demethylase 4A.	0.900
TCAP	LOC102730020	A0A2U3YTG0	A0A2U3Z8B7	Telethonin isoform X2.	Myosin-7-like.	0.481