(18 nodes) Myotube cell development network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CAV2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
	IGF1	Insulin-like growth factor I isoform X1. (153 aa)
	HOMER1	Homer protein homolog 1 isoform X1. (354 aa)
	TMEM182	Transmembrane protein 182. (229 aa)
	LOC102747663	Spermatid-specific manchette-related protein 1-like isoform X1. (164 aa)
	KIAA1161	Uncharacterized family 31 glucosidase KIAA1161 homolog; Belongs to the glycosyl hydrolase 31 family. (714 aa)
	KLHL41	Kelch-like protein 41. (606 aa)
	ACTN1	Alpha-actinin-1. (406 aa)
	LOC102748855	Delta and Notch-like epidermal growth factor-related receptor-like. (297 aa)
	SMYD3	Histone-lysine N-methyltransferase SMYD3. (190 aa)
	LOC102733393	Protein FAM65B-like. (563 aa)
	STAC3	SH3 and cysteine-rich domain-containing protein 3 isoform X1. (364 aa)
	DNER	Delta and Notch-like epidermal growth factor-related receptor. (448 aa)
	BIN3	Bridging integrator 3. (253 aa)
	P2RX2	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (471 aa)
	LOC102725943	Nuclear factor of activated T-cells, cytoplasmic 2-like. (160 aa)
	MYOD1	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
	WNT10B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KIAA1161	LOC102747663	A0A2U3XTC4	A0A2U3XT74	Uncharacterized family 31 glucosidase KIAA1161 homolog; Belongs to the glycosyl hydrolase 31 family.	Spermatid-specific manchette-related protein 1-like isoform X1.	0.544
KLHL41	STAC3	A0A2U3XTP2	A0A2U3Y941	Kelch-like protein 41.	SH3 and cysteine-rich domain-containing protein 3 isoform X1.	0.405
KLHL41	TMEM182	A0A2U3XTP2	A0A2U3XPR6	Kelch-like protein 41.	Transmembrane protein 182.	0.420
LOC102733393	P2RX2	A0A2U3Y6N8	A0A2U3YPZ4	Protein FAM65B-like.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.435
LOC102747663	KIAA1161	A0A2U3XT74	A0A2U3XTC4	Spermatid-specific manchette-related protein 1-like isoform X1.	Uncharacterized family 31 glucosidase KIAA1161 homolog; Belongs to the glycosyl hydrolase 31 family.	0.544
P2RX2	LOC102733393	A0A2U3YPZ4	A0A2U3Y6N8	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	Protein FAM65B-like.	0.435
STAC3	KLHL41	A0A2U3Y941	A0A2U3XTP2	SH3 and cysteine-rich domain-containing protein 3 isoform X1.	Kelch-like protein 41.	0.405
TMEM182	KLHL41	A0A2U3XPR6	A0A2U3XTP2	Transmembrane protein 182.	Kelch-like protein 41.	0.420