(22 nodes) Regulation of smooth muscle cell migration network (Leptonychotes weddellii)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	SEMA6D	semaphorin-6D-like isoform X3; Belongs to the semaphorin family. (1017 aa)
	LOC102738191	Dedicator of cytokinesis protein 4-like isoform X1; Belongs to the DOCK family. (846 aa)
	AIF1	Allograft inflammatory factor 1. (147 aa)
	LOC102737090	Sortilin-related receptor-like. (446 aa)
	PLXNA1	plexin-A1. (1911 aa)
	TRIB1	Tribbles homolog 1. (292 aa)
	BMPR1A	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
	LOC102732300	Abhydrolase domain-containing protein 2-like. (205 aa)
	PRKG1	cGMP-dependent protein kinase 1. (193 aa)
	CORO1B	Coronin; Belongs to the WD repeat coronin family. (489 aa)
	MEF2C	Myocyte-specific enhancer factor 2C-like isoform X2. (473 aa)
	IGFBP5	Insulin-like growth factor-binding protein 5. (271 aa)
	PDGFB	Platelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (241 aa)
	LOC102738536	Insulin-like growth factor-binding protein 3-like. (120 aa)
	NF1	Neurofibromin-like. (1269 aa)
	NDRG4	Protein NDRG4-B isoform X5. (371 aa)
	DOCK7	Dedicator of cytokinesis protein 7 isoform X1; Belongs to the DOCK family. (2129 aa)
	LOC102733752	Abhydrolase domain-containing protein 2-like isoform X1. (241 aa)
	DDR2	Discoidin domain-containing receptor 2-like. (367 aa)
	IGF1	Insulin-like growth factor I isoform X1. (153 aa)
	VTN	Vitronectin. (456 aa)
	LOC102739889	Dedicator of cytokinesis protein 4-like. (137 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IGF1	IGFBP5	A0A2U3XIR6	A0A2U3YN71	Insulin-like growth factor I isoform X1.	Insulin-like growth factor-binding protein 5.	0.572
IGF1	LOC102738536	A0A2U3XIR6	A0A2U3YXA2	Insulin-like growth factor I isoform X1.	Insulin-like growth factor-binding protein 3-like.	0.582
IGFBP5	IGF1	A0A2U3YN71	A0A2U3XIR6	Insulin-like growth factor-binding protein 5.	Insulin-like growth factor I isoform X1.	0.572
IGFBP5	LOC102738536	A0A2U3YN71	A0A2U3YXA2	Insulin-like growth factor-binding protein 5.	Insulin-like growth factor-binding protein 3-like.	0.411
IGFBP5	VTN	A0A2U3YN71	A0A2U3XJY5	Insulin-like growth factor-binding protein 5.	Vitronectin.	0.404
LOC102732300	LOC102733752	A0A2U3YAK7	A0A2U3XNX2	Abhydrolase domain-containing protein 2-like.	Abhydrolase domain-containing protein 2-like isoform X1.	0.933
LOC102733752	LOC102732300	A0A2U3XNX2	A0A2U3YAK7	Abhydrolase domain-containing protein 2-like isoform X1.	Abhydrolase domain-containing protein 2-like.	0.933
LOC102738191	LOC102739889	A0A2U3XYX7	A0A2U3XYQ5	Dedicator of cytokinesis protein 4-like isoform X1; Belongs to the DOCK family.	Dedicator of cytokinesis protein 4-like.	0.956
LOC102738536	IGF1	A0A2U3YXA2	A0A2U3XIR6	Insulin-like growth factor-binding protein 3-like.	Insulin-like growth factor I isoform X1.	0.582
LOC102738536	IGFBP5	A0A2U3YXA2	A0A2U3YN71	Insulin-like growth factor-binding protein 3-like.	Insulin-like growth factor-binding protein 5.	0.411
LOC102739889	LOC102738191	A0A2U3XYQ5	A0A2U3XYX7	Dedicator of cytokinesis protein 4-like.	Dedicator of cytokinesis protein 4-like isoform X1; Belongs to the DOCK family.	0.956
PLXNA1	SEMA6D	A0A2U3Y5W8	A0A2U3X807	plexin-A1.	semaphorin-6D-like isoform X3; Belongs to the semaphorin family.	0.822
SEMA6D	PLXNA1	A0A2U3X807	A0A2U3Y5W8	semaphorin-6D-like isoform X3; Belongs to the semaphorin family.	plexin-A1.	0.822
VTN	IGFBP5	A0A2U3XJY5	A0A2U3YN71	Vitronectin.	Insulin-like growth factor-binding protein 5.	0.404