STRINGSTRING
MSL3 MSL3 LEF1 LEF1 JADE1 JADE1 ING3 ING3 MSL2 MSL2 VPS72 VPS72 DR1 DR1 DMAP1 DMAP1 BRCA2 BRCA2 PAX6 PAX6 MCRS1 MCRS1 KANSL2 KANSL2 BMI1 BMI1 KAT8 KAT8 EP300 EP300 KAT2B KAT2B LOC102726171 LOC102726171 JADE2 JADE2 LOC102732851 LOC102732851 HAT1 HAT1 JADE3 JADE3 TAF6 TAF6 ACTL6B ACTL6B KANSL1 KANSL1 IRF4 IRF4 SUPT3H SUPT3H POLE3 POLE3 LOC102745454 LOC102745454 LOC102744425 LOC102744425 PHF20L1 PHF20L1 ATXN7L1 ATXN7L1 BRPF3 BRPF3 MORF4L2 MORF4L2 ZMPSTE24 ZMPSTE24 RUVBL1 RUVBL1 HNF1A HNF1A ING4 ING4 MRGBP MRGBP GTF2B GTF2B KAT2A KAT2A ATXN7L3 ATXN7L3 TADA3 TADA3 BRPF1 BRPF1 NAA50 NAA50 MBTD1 MBTD1 MECP2 MECP2 TAF12 TAF12 TAF5L TAF5L MBIP MBIP TADA1 TADA1 NCOA1 NCOA1 BEND3 BEND3 ATF2 ATF2 KANSL3 KANSL3 FOXP3 FOXP3 PCGF2 PCGF2 YEATS4 YEATS4 GTF3C4 GTF3C4 TEX30 TEX30 NCOA3 NCOA3 TAF4 TAF4 LOC102728667 LOC102728667 SPHK2 SPHK2 LOC102746722 LOC102746722 ACTL6A ACTL6A MORF4L1 MORF4L1 MSL1 MSL1 CREBBP CREBBP PHF20 PHF20 EP400 EP400 KAT7 KAT7 LOC102729806 LOC102729806 LOC102737651 LOC102737651 OGT OGT ATXN7L2 ATXN7L2 RUVBL2 RUVBL2 ATXN7 ATXN7 MYOD1 MYOD1 ING5 ING5 LOC102750431 LOC102750431 LOC102740668 LOC102740668 LOC102744718 LOC102744718 LOC102748841 LOC102748841
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MSL3Male-specific lethal 3 homolog isoform X1. (522 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (399 aa)
JADE1Protein Jade-1 isoform X1. (843 aa)
ING3Inhibitor of growth protein. (418 aa)
MSL2E3 ubiquitin-protein ligase MSL2 isoform X2. (577 aa)
VPS72Vacuolar protein sorting-associated protein 72 homolog isoform X2. (364 aa)
DR1Protein Dr1 isoform X1. (175 aa)
DMAP1DNA methyltransferase 1-associated protein 1 isoform X1. (468 aa)
BRCA2Breast cancer type 2 susceptibility protein homolog. (2818 aa)
PAX6Paired box protein Pax-6. (221 aa)
MCRS1Microspherule protein 1 isoform X2. (475 aa)
KANSL2KAT8 regulatory NSL complex subunit 2 isoform X2. (492 aa)
BMI1Polycomb complex protein BMI-1 isoform X1. (326 aa)
KAT8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (458 aa)
EP300Histone acetyltransferase p300. (2425 aa)
KAT2BHistone acetyltransferase KAT2B. (735 aa)
LOC102726171LIM domain-binding protein 1-like. (190 aa)
JADE2Protein Jade-2 isoform X2. (784 aa)
LOC102732851LIM domain-binding protein 1-like. (227 aa)
HAT1Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (419 aa)
JADE3Protein Jade-3. (823 aa)
TAF6Transcription initiation factor TFIID subunit 6 isoform X1. (677 aa)
ACTL6BActin-like protein 6B. (130 aa)
KANSL1KAT8 regulatory NSL complex subunit 1 isoform X1. (1103 aa)
IRF4Interferon regulatory factor 4 isoform X1. (451 aa)
SUPT3HTranscription initiation protein SPT3 homolog. (377 aa)
POLE3DNA polymerase epsilon subunit 3. (147 aa)
LOC102745454Nuclear receptor coactivator 3-like. (176 aa)
LOC102744425PHD finger protein 20-like protein 1-like. (166 aa)
PHF20L1PHD finger protein 20-like protein 1-like isoform X1. (592 aa)
ATXN7L1Ataxin-7-like protein 1 isoform X1. (857 aa)
BRPF3Bromodomain and PHD finger-containing protein 3 isoform X1. (1207 aa)
MORF4L2Mortality factor 4-like protein 2 isoform X1. (288 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (175 aa)
HNF1AHepatocyte nuclear factor 1-alpha. (631 aa)
ING4Inhibitor of growth protein. (249 aa)
MRGBPMRG/MORF4L-binding protein. (276 aa)
GTF2BTranscription initiation factor IIB. (316 aa)
KAT2AHistone acetyltransferase KAT2A isoform X2. (838 aa)
ATXN7L3Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (354 aa)
TADA3Transcriptional adapter 3 isoform X1. (432 aa)
BRPF1Peregrin isoform X1. (1220 aa)
NAA50N-alpha-acetyltransferase 50 isoform X1. (169 aa)
MBTD1MBT domain-containing protein 1. (628 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (499 aa)
TAF12Transcription initiation factor TFIID subunit 12 isoform X1. (161 aa)
TAF5Lannotation not available (589 aa)
MBIPMAP3K12-binding inhibitory protein 1 isoform X1. (344 aa)
TADA1Transcriptional adapter 1. (335 aa)
NCOA1Nuclear receptor coactivator. (1441 aa)
BEND3BEN domain-containing protein 3. (828 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X2. (505 aa)
KANSL3KAT8 regulatory NSL complex subunit 3-like isoform X1. (675 aa)
FOXP3Forkhead box protein P3 isoform X1. (456 aa)
PCGF2Polycomb group RING finger protein 2 isoform X1. (371 aa)
YEATS4YEATS domain-containing protein 4. (227 aa)
GTF3C4General transcription factor 3C polypeptide 4. (772 aa)
TEX30Testis-expressed sequence 30 protein isoform X1. (225 aa)
NCOA3Nuclear receptor coactivator 3-like. (1154 aa)
TAF4Transcription initiation factor TFIID subunit 4. (668 aa)
LOC102728667Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (101 aa)
SPHK2Sphingosine kinase 2 isoform X1. (656 aa)
LOC102746722Germinal-center associated nuclear protein-like. (323 aa)
ACTL6AActin-like protein 6A isoform X1; Belongs to the actin family. (429 aa)
MORF4L1Mortality factor 4-like protein 1 isoform X1. (235 aa)
MSL1Male-specific lethal 1 homolog isoform X1. (614 aa)
CREBBPCREB-binding protein-like. (1411 aa)
PHF20PHD finger protein 20. (1013 aa)
EP400E1A-binding protein p400-like. (554 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)
LOC102729806WD repeat-containing protein 5-like. (334 aa)
LOC102737651PHD finger protein 20-like protein 1-like. (183 aa)
OGTUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform X1. (1046 aa)
ATXN7L2Ataxin-7-like protein 2 isoform X2. (701 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (418 aa)
ATXN7Ataxin-7. (650 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
ING5Inhibitor of growth protein. (240 aa)
LOC102750431Enhancer of polycomb homolog 2-like. (357 aa)
LOC102740668RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (335 aa)
LOC102744718Transformation/transcription domain-associated protein-like. (206 aa)
LOC102748841Actin-like protein 6B-like. (150 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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