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CHMP2A CHMP2A LOC102734133 LOC102734133 LRRC15 LRRC15 AXL AXL SMPD1 SMPD1 MVB12A MVB12A MVB12B MVB12B TSG101 TSG101 TNFRSF14 TNFRSF14 VPS4B VPS4B CHMP1A CHMP1A DAG1 DAG1 LOC102730434 LOC102730434 LOC102730737 LOC102730737 LOC102744509 LOC102744509 LOC102726269 LOC102726269 VPS18 VPS18 ZNF639 ZNF639 LOC102730108 LOC102730108 PC PC CHMP1B CHMP1B PVRL2 PVRL2 PVRL4 PVRL4 ADRBK1 ADRBK1 IST1 IST1 FLVCR1 FLVCR1 AVPR1B AVPR1B ANPEP ANPEP LOC102744445 LOC102744445 CLDN1 CLDN1 CHMP7 CHMP7 ATG5 ATG5 GAS6 GAS6 CHMP4A CHMP4A SIVA1 SIVA1 TYRO3 TYRO3 CHMP5 CHMP5 ITGB3 ITGB3 LOC102743181 LOC102743181 CLEC4G CLEC4G NEDD4 NEDD4 VPS4A VPS4A KPNA2 KPNA2 CAV1 CAV1 VTA1 VTA1 PCBP2 PCBP2 PCBP1 PCBP1 CHMP4C CHMP4C RAB1A RAB1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHMP2ACharged multivesicular body protein 2a isoform X1. (222 aa)
LOC102734133Pyruvate carboxylase, mitochondrial-like. (725 aa)
LRRC15Leucine-rich repeat-containing protein 15. (580 aa)
AXLTyrosine-protein kinase receptor UFO. (887 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (625 aa)
MVB12AMultivesicular body subunit 12A. (273 aa)
MVB12BMultivesicular body subunit 12B-like. (292 aa)
TSG101Tumor susceptibility gene 101 protein isoform X1. (391 aa)
TNFRSF14Tumor necrosis factor receptor superfamily member 14. (272 aa)
VPS4BVacuolar protein sorting-associated protein 4B; Belongs to the AAA ATPase family. (444 aa)
CHMP1ACharged multivesicular body protein 1a. (196 aa)
DAG1Dystroglycan isoform X1. (891 aa)
LOC102730434Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
LOC102730737Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa)
LOC102744509Autophagy protein 5-like. (78 aa)
LOC102726269Angiotensin-converting enzyme 2-like. (488 aa)
VPS18Vacuolar protein sorting-associated protein 18 homolog. (895 aa)
ZNF639Zinc finger protein 639. (485 aa)
LOC102730108Neuropilin-1-like. (465 aa)
PCPyruvate carboxylase, mitochondrial. (558 aa)
CHMP1BCharged multivesicular body protein 1b. (199 aa)
PVRL2Poliovirus receptor-related protein 2. (539 aa)
PVRL4Poliovirus receptor-related protein 4 isoform X1. (509 aa)
ADRBK1G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (647 aa)
IST1IST1 homolog isoform X1. (364 aa)
FLVCR1Feline leukemia virus subgroup C receptor-related protein 1. (556 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (420 aa)
ANPEPAminopeptidase. (962 aa)
LOC102744445Integrin beta; Belongs to the integrin beta chain family. (197 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
CHMP7Charged multivesicular body protein 7 isoform X1. (450 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (255 aa)
GAS6Growth arrest-specific protein 6. (646 aa)
CHMP4ALOW QUALITY PROTEIN: charged multivesicular body protein 4a. (265 aa)
SIVA1Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis. (175 aa)
TYRO3Tyrosine-protein kinase receptor TYRO3. (845 aa)
CHMP5Charged multivesicular body protein 5. (232 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (852 aa)
LOC102743181CD209 antigen-like protein 2-like isoform X1. (246 aa)
CLEC4GC-type lectin domain family 4 member G. (293 aa)
NEDD4E3 ubiquitin-protein ligase NEDD4 isoform X1. (1323 aa)
VPS4AVacuolar protein sorting-associated protein 4A; Belongs to the AAA ATPase family. (437 aa)
KPNA2Importin subunit alpha; Functions in nuclear protein import. (529 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
VTA1Vacuolar protein sorting-associated protein VTA1 homolog isoform X1. (279 aa)
PCBP2poly(RC)-binding protein 2 isoform X1. (362 aa)
PCBP1poly(RC)-binding protein 1 isoform X1. (356 aa)
CHMP4CCharged multivesicular body protein 4c. (237 aa)
RAB1ARas-related protein Rab-1A isoform X1. (205 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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