STRINGSTRING
LOC102741857 LOC102741857 GRIK2 GRIK2 RGS21 RGS21 CACNG5 CACNG5 CACNG4 CACNG4 GJD2 GJD2 CHRM5 CHRM5 KCNMB4 KCNMB4 MTOR MTOR CACNG7 CACNG7 KCND1 KCND1 NTRK2 NTRK2 LOC102741496 LOC102741496 PAFAH1B1 PAFAH1B1 KCND3 KCND3 LOC102731583 LOC102731583 KCND2 KCND2 FKBP1B FKBP1B KCNMB2 KCNMB2 KCNMB3 KCNMB3 CACNG2 CACNG2 LOC102743647 LOC102743647 LOC102736727 LOC102736727 DRD5 DRD5 LOC102728180 LOC102728180 LOC102732425 LOC102732425 GPER1 GPER1 KCNA1 KCNA1 LOC102746856 LOC102746856
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102741857Chloride channel protein 1-like. (467 aa)
GRIK2Glutamate receptor ionotropic, kainate 2-like. (841 aa)
RGS21Regulator of G-protein signaling 21. (152 aa)
CACNG5Voltage-dependent calcium channel gamma-5 subunit. (275 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
GJD2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (321 aa)
CHRM5Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (532 aa)
KCNMB4Calcium-activated potassium channel subunit beta-4. (210 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
KCND1Potassium voltage-gated channel subfamily D member 1; Belongs to the potassium channel family. (647 aa)
NTRK2BDNF/NT-3 growth factors receptor-like. (420 aa)
LOC102741496BDNF/NT-3 growth factors receptor-like. (97 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha. (148 aa)
KCND3Potassium voltage-gated channel subfamily D member 3. (283 aa)
LOC102731583Voltage-dependent calcium channel gamma-3 subunit-like. (315 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (629 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
KCNMB2Calcium-activated potassium channel subunit beta-2. (235 aa)
KCNMB3LOW QUALITY PROTEIN: calcium-activated potassium channel subunit beta-3. (281 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (252 aa)
LOC102743647Doublesex and mab-3 related transcription factor 3-like. (383 aa)
LOC102736727Neurofascin-like. (435 aa)
DRD5D(1B) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (432 aa)
LOC102728180Chloride channel protein. (524 aa)
LOC102732425Myelin-associated glycoprotein-like. (382 aa)
GPER1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (370 aa)
KCNA1Potassium voltage-gated channel subfamily A member 1-like; Belongs to the potassium channel family. (495 aa)
LOC102746856Platelet-activating factor acetylhydrolase IB subunit alpha-like isoform X1. (239 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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