STRINGSTRING
PHACTR4 PHACTR4 KIFAP3 KIFAP3 PPP1R3G PPP1R3G STX17 STX17 EIF2AK3 EIF2AK3 CSF1R CSF1R PPP1R3B PPP1R3B MFHAS1 MFHAS1 LOC102728249 LOC102728249 LOC102732199 LOC102732199 LOC102729256 LOC102729256 PPP1R16A PPP1R16A FAM71F1 FAM71F1 MASTL MASTL GNB2L1 GNB2L1 SIRPB1 SIRPB1 LOC102736516 LOC102736516 LOC102735621 LOC102735621 AMBRA1 AMBRA1 LOC102738241 LOC102738241 NEK2 NEK2 PPP1R11 PPP1R11 PPP1R9B PPP1R9B LOC102743045 LOC102743045 JAK3 JAK3 LOC102740157 LOC102740157 PPP6R1 PPP6R1 MTMR4 MTMR4 STAT3 STAT3 PPP1R3C PPP1R3C SH3RF2 SH3RF2 FOXO1 FOXO1 FBXO41 FBXO41 LOC102745944 LOC102745944 ANAPC7 ANAPC7 LOC102749847 LOC102749847 LOC102751021 LOC102751021 FCRL6 FCRL6 BOD1L1 BOD1L1 LOC102750756 LOC102750756 LOC102730789 LOC102730789 JUP JUP ENSA ENSA CTTNBP2NL CTTNBP2NL TCTEX1D4 TCTEX1D4 STRN3 STRN3 PPP1R3A PPP1R3A GNA12 GNA12 CD22 CD22 SKAP2 SKAP2 KCNN4 KCNN4 CLEC12B CLEC12B CLEC12A CLEC12A PHACTR1 PHACTR1 LRRD1 LRRD1 CDKN1B CDKN1B PPP1R10 PPP1R10 PDLIM4 PDLIM4 PAWR PAWR PPP6R2 PPP6R2 SHOC2 SHOC2 KCNQ1 KCNQ1 LOC102732879 LOC102732879 LGALS3 LGALS3 LOC102731375 LOC102731375 LOC102750159 LOC102750159 ANAPC5 ANAPC5 ANAPC4 ANAPC4 LOC102745156 LOC102745156 FBXL2 FBXL2 LOC102739204 LOC102739204 MVP MVP AP3B1 AP3B1 LOC102745161 LOC102745161 AKAP5 AKAP5 TP53 TP53 SLC9A1 SLC9A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PHACTR4Phosphatase and actin regulator. (715 aa)
KIFAP3Kinesin-associated protein 3. (748 aa)
PPP1R3GProtein phosphatase 1 regulatory subunit 3G. (351 aa)
STX17Syntaxin-17; Belongs to the syntaxin family. (302 aa)
EIF2AK3Eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1. (1114 aa)
CSF1RMacrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (961 aa)
PPP1R3BProtein phosphatase 1 regulatory subunit. (285 aa)
MFHAS1Malignant fibrous histiocytoma-amplified sequence 1-like. (1052 aa)
LOC102728249UPF0687 protein C20orf27 homolog isoform X1. (174 aa)
LOC102732199Serine/threonine-protein phosphatase 6 regulatory subunit 3-like. (101 aa)
LOC102729256TNF receptor-associated factor 3-like. (283 aa)
PPP1R16AProtein phosphatase 1 regulatory subunit 16A. (525 aa)
FAM71F1Protein FAM71F1 isoform X1. (344 aa)
MASTLSerine/threonine-protein kinase greatwall isoform X1. (881 aa)
GNB2L1Guanine nucleotide-binding protein subunit beta-2-like 1 isoform X1. (317 aa)
SIRPB1Signal-regulatory protein beta-1 isoform 3. (175 aa)
LOC102736516Phosphatidylinositol 3-kinase regulatory subunit alpha-like. (138 aa)
LOC102735621Cyclin-dependent kinase 1-like. (387 aa)
AMBRA1Activating molecule in BECN1-regulated autophagy protein 1-like. (299 aa)
LOC102738241Mitogen-activated protein kinase kinase kinase 5-like. (795 aa)
NEK2Serine/threonine-protein kinase Nek2. (259 aa)
PPP1R11Protein phosphatase 1 regulatory subunit 11. (126 aa)
PPP1R9BNeurabin-2. (819 aa)
LOC102743045Disabled homolog 2-interacting protein-like. (326 aa)
JAK3Tyrosine-protein kinase. (1139 aa)
LOC102740157Cadherin-5-like; Cadherins are calcium-dependent cell adhesion proteins. (464 aa)
PPP6R1Serine/threonine-protein phosphatase 6 regulatory subunit 1. (877 aa)
MTMR4Myotubularin-related protein 4-like. (585 aa)
STAT3Signal transducer and activator of transcription 3-like. (424 aa)
PPP1R3CProtein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (317 aa)
SH3RF2Putative E3 ubiquitin-protein ligase SH3RF2-like. (521 aa)
FOXO1Forkhead box protein O1-like. (418 aa)
FBXO41F-box only protein 41. (732 aa)
LOC102745944Serine/threonine-protein phosphatase 6 regulatory subunit 3-like. (304 aa)
ANAPC7Anaphase-promoting complex subunit 7. (461 aa)
LOC102749847Tyrosine-protein kinase JAK1-like. (444 aa)
LOC102751021Phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1. (454 aa)
FCRL6LOW QUALITY PROTEIN: Fc receptor-like 6. (490 aa)
BOD1L1Biorientation of chromosomes in cell division protein 1-like 1. (331 aa)
LOC10275075614-3-3 protein epsilon-like; Belongs to the 14-3-3 family. (233 aa)
LOC102730789TNF receptor-associated factor 3-like. (295 aa)
JUPJunction plakoglobin. (307 aa)
ENSAAlpha-endosulfine isoform X1; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (121 aa)
CTTNBP2NLCTTNBP2 N-terminal-like protein. (488 aa)
TCTEX1D4Tctex1 domain-containing protein 4. (219 aa)
STRN3Striatin-3. (713 aa)
PPP1R3AProtein phosphatase 1 regulatory subunit 3A. (1122 aa)
GNA12Guanine nucleotide-binding protein subunit alpha-12 isoform X1. (305 aa)
CD22B-cell receptor CD22 isoform X1. (844 aa)
SKAP2Src kinase-associated phosphoprotein 2. (359 aa)
KCNN4Intermediate conductance calcium-activated potassium channel protein 4. (427 aa)
CLEC12BC-type lectin domain family 12 member B. (276 aa)
CLEC12AC-type lectin domain family 12 member A. (271 aa)
PHACTR1Phosphatase and actin regulator. (486 aa)
LRRD1Leucine-rich repeat and death domain-containing protein 1. (860 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
PPP1R10Serine/threonine-protein phosphatase 1 regulatory subunit 10-like. (839 aa)
PDLIM4PDZ and LIM domain protein 4 isoform X1. (331 aa)
PAWRPRKC apoptosis WT1 regulator protein. (290 aa)
PPP6R2Serine/threonine-protein phosphatase 6 regulatory subunit 2. (937 aa)
SHOC2Leucine-rich repeat protein SHOC-2 isoform X1. (582 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (599 aa)
LOC102732879Disabled homolog 2-interacting protein-like. (454 aa)
LGALS3Galectin. (285 aa)
LOC102731375Biorientation of chromosomes in cell division protein 1-like 1-like. (2673 aa)
LOC102750159Junction plakoglobin-like. (503 aa)
ANAPC5Anaphase-promoting complex subunit 5 isoform X1. (755 aa)
ANAPC4Anaphase-promoting complex subunit 4-like. (280 aa)
LOC102745156Catenin beta-1-like isoform X1. (216 aa)
FBXL2F-box/LRR-repeat protein 2 isoform X1. (423 aa)
LOC102739204Biorientation of chromosomes in cell division protein 1-like. (185 aa)
MVPMajor vault protein. (890 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1092 aa)
LOC102745161Signal transducer and activator of transcription 3-like. (301 aa)
AKAP5A-kinase anchor protein 5. (429 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (817 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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