STRINGSTRING
PIR PIR PDE1B PDE1B CSF2 CSF2 LOC102740057 LOC102740057 LOC102740547 LOC102740547 MED1 MED1 MYH9 MYH9 JUN JUN CSF1 CSF1 IL31RA IL31RA FASN FASN LOC102750359 LOC102750359 LOC102725922 LOC102725922 LOC102730129 LOC102730129
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIRPirin. (132 aa)
PDE1BPhosphodiesterase. (535 aa)
CSF2Granulocyte-macrophage colony-stimulating factor. (153 aa)
LOC102740057Vascular endothelial growth factor A-like isoform X1; Belongs to the PDGF/VEGF growth factor family. (186 aa)
LOC102740547Bone morphogenetic protein 4-like isoform X1. (409 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1582 aa)
MYH9Myosin-9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1845 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (335 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (547 aa)
IL31RAInterleukin-31 receptor subunit alpha-like. (377 aa)
FASNFatty acid synthase. (2519 aa)
LOC102750359Myosin-9-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (163 aa)
LOC102725922THO complex subunit 5 homolog. (212 aa)
LOC102730129Uncharacterized protein LOC102730129. (471 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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