(8 nodes) Notochord development network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EFNA1	ephrin-A1 isoform X1; Belongs to the ephrin family. (205 aa)
	GLI1	Zinc finger protein GLI1 isoform X1. (1105 aa)
	WNT11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	LOC102727345	Transcription factor SOX-9-like. (282 aa)
	YAP1	Yorkie homolog. (326 aa)
	PPP1R35	Protein phosphatase 1 regulatory subunit 35. (264 aa)
	COL2A1	Collagen alpha-1(II) chain isoform X1. (1487 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COL2A1	LOC102727345	A0A2U3XCY5	A0A2U3YND0	Collagen alpha-1(II) chain isoform X1.	Transcription factor SOX-9-like.	0.769
GLI1	LOC102727345	A0A2U3Y8Q9	A0A2U3YND0	Zinc finger protein GLI1 isoform X1.	Transcription factor SOX-9-like.	0.525
LOC102727345	COL2A1	A0A2U3YND0	A0A2U3XCY5	Transcription factor SOX-9-like.	Collagen alpha-1(II) chain isoform X1.	0.769
LOC102727345	GLI1	A0A2U3YND0	A0A2U3Y8Q9	Transcription factor SOX-9-like.	Zinc finger protein GLI1 isoform X1.	0.525
LOC102727345	NOG	A0A2U3YND0	A0A2U3XEL8	Transcription factor SOX-9-like.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.650
NOG	LOC102727345	A0A2U3XEL8	A0A2U3YND0	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	Transcription factor SOX-9-like.	0.650