24 items (Leptonychotes weddellii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	LOC102737831	Serine/threonine-protein kinase D2-like. (246 aa)
	TADA2A	LOW QUALITY PROTEIN: transcriptional adaptor 2A. (306 aa)
	LOC102732559	Apelin receptor-like; Belongs to the G-protein coupled receptor 1 family. (380 aa)
	LOC102741558	Bombesin receptor-activated protein C6orf89 homolog isoform X2. (181 aa)
	ING2	Inhibitor of growth protein. (280 aa)
	LOC102729806	WD repeat-containing protein 5-like. (334 aa)
	SPHK2	Sphingosine kinase 2 isoform X1. (656 aa)
	UCN	Urocortin. (126 aa)
	SDR16C5	Epidermal retinol dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (237 aa)
	FOXP3	Forkhead box protein P3 isoform X1. (456 aa)
	MBIP	MAP3K12-binding inhibitory protein 1 isoform X1. (344 aa)
	TADA3	Transcriptional adapter 3 isoform X1. (432 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
	KAT2A	Histone acetyltransferase KAT2A isoform X2. (838 aa)
	PINK1	Serine/threonine-protein kinase PINK1, mitochondrial. (488 aa)
	BCL6	B-cell lymphoma 6 protein. (706 aa)
	LOC102748554	Bombesin receptor-activated protein C6orf89 homolog. (142 aa)
	AKAP8L	A-kinase anchor protein 8-like; Belongs to the AKAP95 family. (648 aa)
	SMARCA5	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5. (1052 aa)
	RRP8	Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (457 aa)
	NIPBL	Nipped-B protein. (2803 aa)
	LOC102727574	Protein arginine N-methyltransferase 6-like; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (375 aa)
	DR1	Protein Dr1 isoform X1. (175 aa)
	LRRK2	Leucine-rich repeat serine/threonine-protein kinase 2. (2150 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL6	FOXP3	A0A2U3Y0T0	A0A2U3YH69	B-cell lymphoma 6 protein.	Forkhead box protein P3 isoform X1.	0.786
BCL6	TP53	A0A2U3Y0T0	A0A2U3Y5G3	B-cell lymphoma 6 protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.584
DR1	KAT2A	A0A2U3XBU0	A0A2U3Y4H3	Protein Dr1 isoform X1.	Histone acetyltransferase KAT2A isoform X2.	0.593
DR1	LOC102729806	A0A2U3XBU0	A0A2U3Z0A5	Protein Dr1 isoform X1.	WD repeat-containing protein 5-like.	0.687
DR1	MBIP	A0A2U3XBU0	A0A2U3YB75	Protein Dr1 isoform X1.	MAP3K12-binding inhibitory protein 1 isoform X1.	0.846
DR1	TADA2A	A0A2U3XBU0	A0A2U3Z920	Protein Dr1 isoform X1.	LOW QUALITY PROTEIN: transcriptional adaptor 2A.	0.892
DR1	TADA3	A0A2U3XBU0	A0A2U3Y5R5	Protein Dr1 isoform X1.	Transcriptional adapter 3 isoform X1.	0.844
FOXP3	BCL6	A0A2U3YH69	A0A2U3Y0T0	Forkhead box protein P3 isoform X1.	B-cell lymphoma 6 protein.	0.786
ING2	LOC102729806	A0A2U3Z0V0	A0A2U3Z0A5	Inhibitor of growth protein.	WD repeat-containing protein 5-like.	0.509
ING2	TP53	A0A2U3Z0V0	A0A2U3Y5G3	Inhibitor of growth protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.463
KAT2A	DR1	A0A2U3Y4H3	A0A2U3XBU0	Histone acetyltransferase KAT2A isoform X2.	Protein Dr1 isoform X1.	0.593
KAT2A	LOC102727574	A0A2U3Y4H3	A0A2U3XC01	Histone acetyltransferase KAT2A isoform X2.	Protein arginine N-methyltransferase 6-like; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.478
KAT2A	LOC102729806	A0A2U3Y4H3	A0A2U3Z0A5	Histone acetyltransferase KAT2A isoform X2.	WD repeat-containing protein 5-like.	0.903
KAT2A	MBIP	A0A2U3Y4H3	A0A2U3YB75	Histone acetyltransferase KAT2A isoform X2.	MAP3K12-binding inhibitory protein 1 isoform X1.	0.484
KAT2A	SMARCA5	A0A2U3Y4H3	A0A2U3XU58	Histone acetyltransferase KAT2A isoform X2.	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5.	0.770
KAT2A	TADA2A	A0A2U3Y4H3	A0A2U3Z920	Histone acetyltransferase KAT2A isoform X2.	LOW QUALITY PROTEIN: transcriptional adaptor 2A.	0.942
KAT2A	TADA3	A0A2U3Y4H3	A0A2U3Y5R5	Histone acetyltransferase KAT2A isoform X2.	Transcriptional adapter 3 isoform X1.	0.996
KAT2A	TP53	A0A2U3Y4H3	A0A2U3Y5G3	Histone acetyltransferase KAT2A isoform X2.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.618
LOC102727574	KAT2A	A0A2U3XC01	A0A2U3Y4H3	Protein arginine N-methyltransferase 6-like; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Histone acetyltransferase KAT2A isoform X2.	0.478
LOC102729806	DR1	A0A2U3Z0A5	A0A2U3XBU0	WD repeat-containing protein 5-like.	Protein Dr1 isoform X1.	0.687