STRINGSTRING
FAM46D FAM46D LOC102729474 LOC102729474 RBM46 RBM46 LOC102747519 LOC102747519 TRIM61 TRIM61 LRRK2 LRRK2 RBM24 RBM24 LOC102750290 LOC102750290 BOLL BOLL UCHL5 UCHL5 CSDE1 CSDE1 PARN PARN TREM2 TREM2 LOC102741936 LOC102741936 WNT1 WNT1 DHX9 DHX9 IGF2BP3 IGF2BP3 SYNCRIP SYNCRIP SCFD1 SCFD1 FUS FUS METTL20 METTL20 UBXN1 UBXN1 TMEM39A TMEM39A CAMLG CAMLG LOC102731945 LOC102731945 LOC102730419 LOC102730419 DND1 DND1 PAPD4 PAPD4 ELAVL4 ELAVL4 RBM10 RBM10 DDRGK1 DDRGK1 TIMP1 TIMP1 GLTPD1 GLTPD1 GIPC2 GIPC2 TSPO TSPO USP14 USP14 IGF2BP2 IGF2BP2 EIF4ENIF1 EIF4ENIF1 ELAVL1 ELAVL1 NUPR1 NUPR1 TIMP4 TIMP4 PABPN1L PABPN1L IL10 IL10 TMEM39B TMEM39B LOC102728317 LOC102728317 HTR2B HTR2B LOC102743592 LOC102743592 EIF3H EIF3H PDCL3 PDCL3 DAPL1 DAPL1 HNRNPAB HNRNPAB TRAF3IP2 TRAF3IP2 MTOR MTOR STYX STYX HIPK2 HIPK2 VIP VIP FAM46A FAM46A PHAX PHAX RNF5 RNF5 TIMP3 TIMP3 THRAP3 THRAP3 UBQLN4 UBQLN4 QSOX1 QSOX1 DKC1 DKC1 FEZ2 FEZ2 RPL11 RPL11 MFSD2A MFSD2A LOC102729145 LOC102729145 GIPC1 GIPC1 PINK1 PINK1 EHMT2 EHMT2 BAG6 BAG6 LOC102745161 LOC102745161 LOC102737090 LOC102737090 CHMP4A CHMP4A GIPC3 GIPC3 TP53 TP53 PHF23 PHF23 GPLD1 GPLD1 SIRT2 SIRT2 DHX34 DHX34 FAM46B FAM46B KDM4A KDM4A LOC102740301 LOC102740301 FOXK2 FOXK2 LOC102734294 LOC102734294 PML PML A1CF A1CF CCAR2 CCAR2 IGF2BP1 IGF2BP1 TTC36 TTC36 PKP3 PKP3 LOC102748381 LOC102748381 DHX36 DHX36 ANGEL2 ANGEL2 DAZL DAZL LOC102741308 LOC102741308 LOC102740119 LOC102740119 LOC102740715 LOC102740715 WAC WAC LOC102730059 LOC102730059 ZFP36 ZFP36 LOC102740611 LOC102740611 IL10RA IL10RA FMR1 FMR1 MTMR9 MTMR9 LOC102744361 LOC102744361 LZTS1 LZTS1 HNRNPD HNRNPD NRBP2 NRBP2 LOC102746422 LOC102746422 LOC102731310 LOC102731310 LOC102742137 LOC102742137 LOC102741529 LOC102741529 PARK7 PARK7 LOC102746625 LOC102746625 ZCCHC17 ZCCHC17 LOC102729692 LOC102729692 LEP LEP NRDE2 NRDE2 DFFB DFFB BAG5 BAG5 SMCR8 SMCR8 OGT OGT LOC102737253 LOC102737253 WDR6 WDR6 LOC102746954 LOC102746954 MYD88 MYD88 INS INS LOC102737163 LOC102737163 LOC102750129 LOC102750129 HNRNPU HNRNPU STAT3 STAT3 LOC102734159 LOC102734159 CTSA CTSA LOC102741272 LOC102741272 LOC102732459 LOC102732459 LOC102743697 LOC102743697
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FAM46DProtein FAM46D. (390 aa)
LOC102729474Putative tripartite motif-containing protein 75-like. (469 aa)
RBM46Probable RNA-binding protein 46 isoform X1. (533 aa)
LOC102747519Tripartite motif-containing protein 60-like. (474 aa)
TRIM61Tripartite motif-containing protein 60. (470 aa)
LRRK2Leucine-rich repeat serine/threonine-protein kinase 2. (2150 aa)
RBM24RNA-binding protein 24. (116 aa)
LOC102750290Polyadenylate-binding protein 1-like. (311 aa)
BOLLProtein boule-like isoform X1. (293 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (329 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (845 aa)
PARNpoly(A)-specific ribonuclease PARN isoform X1. (638 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (261 aa)
LOC102741936Trem-like transcript 1 protein-like. (128 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
DHX9ATP-dependent RNA helicase A. (1276 aa)
IGF2BP3Insulin-like growth factor 2 mRNA-binding protein 3 isoform X2. (580 aa)
SYNCRIPHeterogeneous nuclear ribonucleoprotein Q isoform X1. (623 aa)
SCFD1Sec1 family domain-containing protein 1 isoform X1; Belongs to the STXBP/unc-18/SEC1 family. (641 aa)
FUSRNA-binding protein FUS isoform X1. (517 aa)
METTL20Methyltransferase-like protein 20. (266 aa)
UBXN1UBX domain-containing protein 1 isoform X2. (295 aa)
TMEM39ATransmembrane protein 39A. (488 aa)
CAMLGCalcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (296 aa)
LOC102731945Suppressor of fused homolog. (106 aa)
LOC102730419Fasciculation and elongation protein zeta-1-like. (104 aa)
DND1Dead end protein homolog 1. (353 aa)
PAPD4poly(A) RNA polymerase GLD2 isoform X1. (484 aa)
ELAVL4ELAV-like protein; Belongs to the RRM elav family. (380 aa)
RBM10RNA-binding protein 10 isoform X1. (1071 aa)
DDRGK1DDRGK domain-containing protein 1. (315 aa)
TIMP1Metalloproteinase inhibitor 1. (207 aa)
GLTPD1Ceramide-1-phosphate transfer protein. (214 aa)
GIPC2PDZ domain-containing protein GIPC2. (312 aa)
TSPOTranslocator protein. (170 aa)
USP14Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (494 aa)
IGF2BP2Insulin-like growth factor 2 mRNA-binding protein 2 isoform X1. (599 aa)
EIF4ENIF1Eukaryotic translation initiation factor 4E transporter isoform X1. (987 aa)
ELAVL1ELAV-like protein; Belongs to the RRM elav family. (326 aa)
NUPR1Nuclear protein 1 isoform X1. (82 aa)
TIMP4Metalloproteinase inhibitor 4. (224 aa)
PABPN1LLOW QUALITY PROTEIN: embryonic polyadenylate-binding protein 2. (299 aa)
IL10Interleukin-10. (178 aa)
TMEM39BTransmembrane protein 39B. (492 aa)
LOC102728317Myotubularin-related protein 9-like. (542 aa)
HTR2B5-hydroxytryptamine receptor 2B. (526 aa)
LOC102743592Metalloproteinase inhibitor 2-like. (209 aa)
EIF3HEukaryotic translation initiation factor 3 subunit H. (235 aa)
PDCL3Phosducin-like protein 3. (239 aa)
DAPL1Death-associated protein-like 1. (107 aa)
HNRNPABHeterogeneous nuclear ribonucleoprotein A/B isoform X1. (259 aa)
TRAF3IP2Adapter protein CIKS isoform X1. (563 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
STYXSerine/threonine/tyrosine-interacting protein. (223 aa)
HIPK2Homeodomain-interacting protein kinase 2-like isoform X1. (1188 aa)
VIPVIP peptides isoform X1. (170 aa)
FAM46AProtein FAM46A-like isoform X2. (434 aa)
PHAXPhosphorylated adapter RNA export protein. (394 aa)
RNF5E3 ubiquitin-protein ligase RNF5. (180 aa)
TIMP3Metalloproteinase inhibitor 3. (143 aa)
THRAP3Thyroid hormone receptor-associated protein 3 isoform X2. (957 aa)
UBQLN4Ubiquilin-4. (601 aa)
QSOX1Sulfhydryl oxidase. (442 aa)
DKC1H/ACA ribonucleoprotein complex subunit 4 isoform X1. (517 aa)
FEZ2Fasciculation and elongation protein zeta-2. (297 aa)
RPL1160S ribosomal protein L11 isoform X2; Belongs to the universal ribosomal protein uL5 family. (178 aa)
MFSD2AMajor facilitator superfamily domain-containing protein 2A isoform X1. (529 aa)
LOC102729145Eukaryotic translation initiation factor 4 gamma 1-like. (207 aa)
GIPC1PDZ domain-containing protein GIPC1. (333 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial. (488 aa)
EHMT2Histone-lysine N-methyltransferase EHMT2 isoform X1. (1268 aa)
BAG6Large proline-rich protein BAG6 isoform X1. (1163 aa)
LOC102745161Signal transducer and activator of transcription 3-like. (301 aa)
LOC102737090Sortilin-related receptor-like. (446 aa)
CHMP4ALOW QUALITY PROTEIN: charged multivesicular body protein 4a. (265 aa)
GIPC3PDZ domain-containing protein GIPC3. (312 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
PHF23PHD finger protein 23 isoform X1. (403 aa)
GPLD1Phosphatidylinositol-glycan-specific phospholipase D. (840 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa)
DHX34Probable ATP-dependent RNA helicase DHX34. (1136 aa)
FAM46BProtein FAM46B. (427 aa)
KDM4ALysine-specific demethylase 4A. (480 aa)
LOC102740301Fasciculation and elongation protein zeta-1-like. (247 aa)
FOXK2Forkhead box protein K2. (540 aa)
LOC102734294Protein Tob1-like isoform X1. (336 aa)
PMLProtein PML. (880 aa)
A1CFAPOBEC1 complementation factor. (592 aa)
CCAR2Cell cycle and apoptosis regulator protein 2. (918 aa)
IGF2BP1Insulin-like growth factor 2 mRNA-binding protein 1 isoform X1. (577 aa)
TTC36Tetratricopeptide repeat protein 36. (189 aa)
PKP3Plakophilin-3 isoform X1. (810 aa)
LOC102748381Inhibitor of nuclear factor kappa-B kinase subunit epsilon-like. (618 aa)
DHX36Probable ATP-dependent RNA helicase DHX36 isoform X1. (1011 aa)
ANGEL2Protein angel homolog 2 isoform X1. (544 aa)
DAZLDeleted in azoospermia-like. (302 aa)
LOC102741308Protein FAM46C-like. (391 aa)
LOC102740119RNA-binding protein 38-like. (216 aa)
LOC102740715Bis(5'-adenosyl)-triphosphatase-like. (163 aa)
WACWW domain-containing adapter protein with coiled-coil-like isoform X1. (646 aa)
LOC102730059TBC1 domain family member 14-like. (241 aa)
ZFP36Tristetraprolin. (325 aa)
LOC102740611TNF receptor-associated factor. (490 aa)
IL10RAInterleukin-10 receptor subunit alpha. (575 aa)
FMR1Fragile X mental retardation protein 1-like isoform X2. (547 aa)
MTMR9Myotubularin-related protein 9. (549 aa)
LOC102744361Small glutamine-rich tetratricopeptide repeat-containing protein alpha-like. (76 aa)
LZTS1Leucine zipper putative tumor suppressor 1 isoform X1. (606 aa)
HNRNPDHeterogeneous nuclear ribonucleoprotein D0 isoform X1. (355 aa)
NRBP2Nuclear receptor-binding protein 2. (499 aa)
LOC102746422Plakophilin-1-like. (564 aa)
LOC102731310Leucine-rich PPR motif-containing protein, mitochondrial-like. (962 aa)
LOC102742137Leucine-rich PPR motif-containing protein, mitochondrial-like. (112 aa)
LOC102741529Leucine-rich PPR motif-containing protein, mitochondrial-like. (231 aa)
PARK7Protein DJ-1 isoform X1. (189 aa)
LOC102746625Lysine-specific demethylase 4A-like. (404 aa)
ZCCHC17Nucleolar protein of 40 kDa isoform X1. (241 aa)
LOC102729692Ras-interacting protein 1-like. (208 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (166 aa)
NRDE2Protein NRDE2 homolog. (1168 aa)
DFFBDNAation factor subunit beta. (341 aa)
BAG5BAG family molecular chaperone regulator 5. (448 aa)
SMCR8smith-Magenis syndrome chromosomal region candidate gene 8 protein. (937 aa)
OGTUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform X1. (1046 aa)
LOC102737253Glial cell line-derived neurotrophic factor-like isoform X1. (211 aa)
WDR6WD repeat-containing protein 6. (1120 aa)
LOC102746954Fructose-2,6-bisphosphatase TIGAR. (270 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
LOC102737163Tyrosine-protein phosphatase non-receptor type 3-like. (442 aa)
LOC102750129Uncharacterized protein. (429 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U isoform X1. (825 aa)
STAT3Signal transducer and activator of transcription 3-like. (424 aa)
LOC102734159Small glutamine-rich tetratricopeptide repeat-containing protein alpha-like. (266 aa)
CTSACarboxypeptidase; Belongs to the peptidase S10 family. (495 aa)
LOC102741272Protein CLEC16A-like. (284 aa)
LOC102732459E3 ubiquitin-protein ligase NRDP1-like. (317 aa)
LOC102743697Probable ubiquitin carboxyl-terminal hydrolase FAF-X-like. (164 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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