STRINGSTRING
LOC102730919 LOC102730919 LOC102735431 LOC102735431 UPF1 UPF1 S100A14 S100A14 S100A9 S100A9 TGFB1 TGFB1 AXL AXL LOC102729790 LOC102729790 AKIRIN2 AKIRIN2 CCR7 CCR7 NR1D1 NR1D1 PTGIR PTGIR MEF2C MEF2C LOC102739627 LOC102739627 LOC102735415 LOC102735415 CXCL11 CXCL11 CXCL10 CXCL10 IRF8 IRF8 MAPK1 MAPK1 ZFP36 ZFP36 CXCL13 CXCL13 CMPK2 CMPK2 PAF1 PAF1 CD180 CD180 NOD2 NOD2 ADH5 ADH5 VIMP VIMP BCL10 BCL10 ELANE ELANE CITED1 CITED1 LOC102728244 LOC102728244 LOC102736999 LOC102736999 LOC102746290 LOC102746290 PTAFR PTAFR TRIB1 TRIB1 NFKBIB NFKBIB PLSCR3 PLSCR3 TBXA2R TBXA2R CACTIN CACTIN OTUD5 OTUD5 TNF TNF LOC102742895 LOC102742895 CLEC17A CLEC17A PTGER1 PTGER1 ANKRD1 ANKRD1 HMGB2 HMGB2 PDCD1LG2 PDCD1LG2 LY96 LY96 PLAA PLAA P2RX7 P2RX7 TICAM2 TICAM2 TRAF6 TRAF6 TNIP2 TNIP2 LOC102732823 LOC102732823 PLSCR4 PLSCR4 LOC102733534 LOC102733534 CTR9 CTR9 TREM2 TREM2 LOC102741936 LOC102741936 LOC102749618 LOC102749618 STAP1 STAP1 IL8 IL8 PPBP PPBP PF4 PF4 PYCARD PYCARD CXCL6 CXCL6 NR1H3 NR1H3 HAVCR2 HAVCR2 CD80 CD80 WDR83 WDR83 LOC102751010 LOC102751010 GCH1 GCH1 LOC102740172 LOC102740172 LOC102736765 LOC102736765 LOC102740880 LOC102740880 LOC102732879 LOC102732879 MRC1 MRC1 PDE4B PDE4B IRG1 IRG1 IL12RB2 IL12RB2 IL23R IL23R F2R F2R ABL1 ABL1 CCDC142 CCDC142 TNFAIP3 TNFAIP3 TNFSF4 TNFSF4 CHMP5 CHMP5 LOC102731157 LOC102731157 IL10 IL10 PTGER4 PTGER4 ERBB2IP ERBB2IP PTGFR PTGFR LIAS LIAS NFKBIA NFKBIA KLRK1 KLRK1 IDO1 IDO1 CEBPB CEBPB LOC102745857 LOC102745857 LOC102741172 LOC102741172 LOC102741358 LOC102741358 LOC102748833 LOC102748833 LOC102729925 LOC102729925 SRR SRR CCR5 CCR5 LOC102737260 LOC102737260 LOC102734950 LOC102734950 MYD88 MYD88 LOC102746660 LOC102746660 LOC102734039 LOC102734039 LOC102730527 LOC102730527 LOC102750017 LOC102750017 LOC102738254 LOC102738254 IFNAR1 IFNAR1 LOC102743045 LOC102743045 IL1F10 IL1F10 LOC102751087 LOC102751087
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102730919Interleukin-1. (150 aa)
LOC102735431C-C motif chemokine. (93 aa)
UPF1Regulator of nonsense transcripts 1-like. (373 aa)
S100A14Protein S100-A14; Belongs to the S-100 family. (104 aa)
S100A9Protein S100; Belongs to the S-100 family. (140 aa)
TGFB1Transforming growth factor beta-1. (261 aa)
AXLTyrosine-protein kinase receptor UFO. (887 aa)
LOC102729790Regulator of nonsense transcripts 1-like. (678 aa)
AKIRIN2Akirin-2. (115 aa)
CCR7c-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. (390 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (613 aa)
PTGIRProstacyclin receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa)
MEF2CMyocyte-specific enhancer factor 2C-like isoform X2. (473 aa)
LOC102739627Interleukin-1. (155 aa)
LOC102735415Phosphoinositide phospholipase C. (309 aa)
CXCL11c-X-C motif chemokine 11. (100 aa)
CXCL10C-X-C motif chemokine. (98 aa)
IRF8Interferon regulatory factor 8. (426 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (326 aa)
ZFP36Tristetraprolin. (325 aa)
CXCL13c-X-C motif chemokine 13. (110 aa)
CMPK2UMP-CMP kinase 2, mitochondrial. (359 aa)
PAF1RNA polymerase II-associated factor 1 homolog isoform X2. (528 aa)
CD180CD180 antigen. (661 aa)
NOD2Nucleotide-binding oligomerization domain-containing protein 2. (1013 aa)
ADH5S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa)
VIMPSelenoprotein S. (188 aa)
BCL10B-cell lymphoma/leukemia 10 isoform X1. (233 aa)
ELANELOW QUALITY PROTEIN: neutrophil elastase; Belongs to the peptidase S1 family. (284 aa)
CITED1Cbp/p300-interacting transactivator 1 isoform X2. (197 aa)
LOC102728244Interleukin-1 receptor-associated kinase 1-like. (299 aa)
LOC102736999Dual specificity protein phosphatase 10-like; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (177 aa)
LOC10274629025-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial-like; Belongs to the cytochrome P450 family. (508 aa)
PTAFRPlatelet-activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (344 aa)
TRIB1Tribbles homolog 1. (292 aa)
NFKBIBNF-kappa-B inhibitor beta isoform X2. (354 aa)
PLSCR3Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (287 aa)
TBXA2RThromboxane A2 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (343 aa)
CACTINCactin. (749 aa)
OTUD5OTU domain-containing protein 5 isoform X1. (376 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
LOC102742895NF-kappa-B inhibitor-like protein 1-like. (255 aa)
CLEC17AC-type lectin domain family 17, member A. (328 aa)
PTGER1Prostaglandin E2 receptor EP1 subtype. (149 aa)
ANKRD1Ankyrin repeat domain-containing protein 1. (319 aa)
HMGB2High mobility group protein B2 isoform X1. (210 aa)
PDCD1LG2Programmed cell death 1 ligand 2. (273 aa)
LY96Lymphocyte antigen 96 isoform X1. (160 aa)
PLAAPhospholipase A-2-activating protein. (639 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (591 aa)
TICAM2TIR domain-containing adapter molecule 2. (238 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
TNIP2TNFAIP3-interacting protein 2. (432 aa)
LOC102732823Vimentin-like isoform X1; Belongs to the intermediate filament family. (466 aa)
PLSCR4Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (330 aa)
LOC102733534Protein LDOC1-like. (149 aa)
CTR9RNA polymerase-associated protein CTR9 homolog. (723 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (261 aa)
LOC102741936Trem-like transcript 1 protein-like. (128 aa)
LOC102749618Toll-like receptor 4-like; Belongs to the Toll-like receptor family. (793 aa)
STAP1Signal-transducing adaptor protein 1. (332 aa)
IL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (104 aa)
PPBPLOW QUALITY PROTEIN: platelet basic protein. (119 aa)
PF4C-X-C motif chemokine. (106 aa)
PYCARDApoptosis-associated speck-like protein containing a CARD isoform X1. (194 aa)
CXCL6C-X-C motif chemokine. (113 aa)
NR1H3Oxysterols receptor LXR-alpha isoform X1. (456 aa)
HAVCR2Hepatitis A virus cellular receptor 2. (280 aa)
CD80LOW QUALITY PROTEIN: T-lymphocyte activation antigen CD80. (295 aa)
WDR83WD repeat domain-containing protein 83. (315 aa)
LOC102751010Nitric oxide synthase, inducible-like. (531 aa)
GCH1GTP cyclohydrolase 1. (249 aa)
LOC102740172Lipopolysaccharide-binding protein-like. (97 aa)
LOC102736765Interleukin-1 receptor-associated kinase 3-like. (125 aa)
LOC102740880Nitric oxide synthase, endothelial-like. (619 aa)
LOC102732879Disabled homolog 2-interacting protein-like. (454 aa)
MRC1Macrophage mannose receptor 1. (1000 aa)
PDE4BcAMP-specific 3',5'-cyclic phosphodiesterase 4B. (284 aa)
IRG1Cis-aconitate decarboxylase. (481 aa)
IL12RB2Interleukin-12 receptor subunit beta-2. (851 aa)
IL23RInterleukin-23 receptor. (631 aa)
F2RProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
ABL1Tyrosine-protein kinase ABL1-like. (312 aa)
CCDC142Coiled-coil domain-containing protein 142. (766 aa)
TNFAIP3Tumor necrosis factor alpha-induced protein 3. (790 aa)
TNFSF4Tumor necrosis factor ligand superfamily member 4; Belongs to the tumor necrosis factor family. (183 aa)
CHMP5Charged multivesicular body protein 5. (232 aa)
LOC102731157ARF GTPase-activating protein GIT1-like. (191 aa)
IL10Interleukin-10. (178 aa)
PTGER4Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (489 aa)
ERBB2IPProtein LAP2 isoform X1. (1460 aa)
PTGFRProstaglandin F2-alpha receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
LIASLipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (373 aa)
NFKBIANF-kappa-B inhibitor alpha isoform X2. (314 aa)
KLRK1NKG2-D type II integral membrane protein. (216 aa)
IDO1Indoleamine 2,3-dioxygenase 1. (394 aa)
CEBPBCCAAT/enhancer-binding protein. (345 aa)
LOC102745857Phosphodiesterase. (503 aa)
LOC102741172Carbamoyl-phosphate synthase [ammonia], mitochondrial-like. (179 aa)
LOC102741358Protein S100; Belongs to the S-100 family. (89 aa)
LOC102748833Tyrosine-protein kinase. (375 aa)
LOC102729925B1 bradykinin receptor-like. (343 aa)
SRRSerine racemase. (350 aa)
CCR5c-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (352 aa)
LOC102737260Macrophage mannose receptor 1-like. (457 aa)
LOC102734950Forkhead box protein P1-like. (351 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
LOC102746660RNA polymerase-associated protein CTR9 homolog. (452 aa)
LOC102734039Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog. (161 aa)
LOC102730527Breakpoint cluster region protein-like. (172 aa)
LOC102750017Mothers against decapentaplegic homolog 6-like. (181 aa)
LOC102738254Vimentin-like; Belongs to the intermediate filament family. (209 aa)
IFNAR1Interferon alpha/beta receptor 1. (560 aa)
LOC102743045Disabled homolog 2-interacting protein-like. (326 aa)
IL1F10Interleukin-1. (152 aa)
LOC102751087Nitric oxide synthase, inducible-like. (430 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.