(13 nodes) Negative regulation of interleukin-2 production network (Leptonychotes weddellii)

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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Predicted Interactions

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Your Input:
	ZFP36	Tristetraprolin. (325 aa)
	TBX21	T-box transcription factor TBX21. (535 aa)
	HOMER3	Homer protein homolog 3 isoform X1. (359 aa)
	PRNP	Major prion protein; Belongs to the prion family. (257 aa)
	GATA3	Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
	FOXP3	Forkhead box protein P3 isoform X1. (456 aa)
	NOD2	Nucleotide-binding oligomerization domain-containing protein 2. (1013 aa)
	NAV3	Neuron navigator 3-like. (497 aa)
	TNFAIP3	Tumor necrosis factor alpha-induced protein 3. (790 aa)
	LOC102751229	Zinc finger protein RFP-like isoform X1. (513 aa)
	LAG3	Lymphocyte activation gene 3 protein. (389 aa)
	HDAC7	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (928 aa)
	VSIG4	V-set and immunoglobulin domain-containing protein 4 isoform X1. (399 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FOXP3	GATA3	A0A2U3YH69	A0A2U3YCA3	Forkhead box protein P3 isoform X1.	Trans-acting T-cell-specific transcription factor GATA-3 isoform X1.	0.793
FOXP3	HDAC7	A0A2U3YH69	A0A2U3Y690	Forkhead box protein P3 isoform X1.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.525
FOXP3	LAG3	A0A2U3YH69	A0A2U3Y2M1	Forkhead box protein P3 isoform X1.	Lymphocyte activation gene 3 protein.	0.652
FOXP3	TBX21	A0A2U3YH69	A0A2U3YMK5	Forkhead box protein P3 isoform X1.	T-box transcription factor TBX21.	0.609
GATA3	FOXP3	A0A2U3YCA3	A0A2U3YH69	Trans-acting T-cell-specific transcription factor GATA-3 isoform X1.	Forkhead box protein P3 isoform X1.	0.793
GATA3	TBX21	A0A2U3YCA3	A0A2U3YMK5	Trans-acting T-cell-specific transcription factor GATA-3 isoform X1.	T-box transcription factor TBX21.	0.952
HDAC7	FOXP3	A0A2U3Y690	A0A2U3YH69	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Forkhead box protein P3 isoform X1.	0.525
LAG3	FOXP3	A0A2U3Y2M1	A0A2U3YH69	Lymphocyte activation gene 3 protein.	Forkhead box protein P3 isoform X1.	0.652
LAG3	TBX21	A0A2U3Y2M1	A0A2U3YMK5	Lymphocyte activation gene 3 protein.	T-box transcription factor TBX21.	0.472
NOD2	TNFAIP3	A0A2U3YF51	A0A2U3XU44	Nucleotide-binding oligomerization domain-containing protein 2.	Tumor necrosis factor alpha-induced protein 3.	0.543
TBX21	FOXP3	A0A2U3YMK5	A0A2U3YH69	T-box transcription factor TBX21.	Forkhead box protein P3 isoform X1.	0.609
TBX21	GATA3	A0A2U3YMK5	A0A2U3YCA3	T-box transcription factor TBX21.	Trans-acting T-cell-specific transcription factor GATA-3 isoform X1.	0.952
TBX21	LAG3	A0A2U3YMK5	A0A2U3Y2M1	T-box transcription factor TBX21.	Lymphocyte activation gene 3 protein.	0.472
TNFAIP3	NOD2	A0A2U3XU44	A0A2U3YF51	Tumor necrosis factor alpha-induced protein 3.	Nucleotide-binding oligomerization domain-containing protein 2.	0.543