STRINGSTRING
FOXA1 FOXA1 LOC102732257 LOC102732257 YAP1 YAP1 MED1 MED1 LOC102732116 LOC102732116 PAK1 PAK1 PAGR1 PAGR1 LOC102748673 LOC102748673
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FOXA1Hepatocyte nuclear factor 3-alpha. (473 aa)
LOC102732257Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (469 aa)
YAP1Yorkie homolog. (326 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1582 aa)
LOC102732116Follicle-stimulating hormone receptor-like. (181 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
PAGR1PAXIP1-associated glutamate-rich protein 1. (254 aa)
LOC102748673Uncharacterized protein C1orf64-like. (169 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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