STRINGSTRING
FAM46B FAM46B FXR2 FXR2 EIF5A EIF5A UHMK1 UHMK1 EEF2 EEF2 TNF TNF RBM3 RBM3 PINK1 PINK1 LOC102732056 LOC102732056 HNRNPU HNRNPU RPS6KB2 RPS6KB2 DDX3X DDX3X EIF4G1 EIF4G1 LOC102730635 LOC102730635 LOC102729145 LOC102729145 EIF5A2 EIF5A2 MTOR MTOR LOC102741681 LOC102741681 RMND1 RMND1 LARP4 LARP4 EFNA1 EFNA1 METTL5 METTL5 BCL3 BCL3 PIWIL2 PIWIL2 LOC102738532 LOC102738532 NCK2 NCK2 LOC102738254 LOC102738254 DHX9 DHX9 WIBG WIBG TARBP2 TARBP2 CSDE1 CSDE1 GSK3A GSK3A LOC102728198 LOC102728198 KRT17 KRT17 NFE2L2 NFE2L2 MPV17L2 MPV17L2 EIF3D EIF3D SPHK2 SPHK2 NGRN NGRN FMR1 FMR1 CASP3 CASP3 ZCCHC4 ZCCHC4 METTL14 METTL14 LOC102732107 LOC102732107 UCN UCN EPHA4 EPHA4 LARP6 LARP6 LOC102737030 LOC102737030 USP16 USP16 EIF2S3 EIF2S3 RPS9 RPS9 CNBP CNBP NOD2 NOD2 DAZL DAZL THBS1 THBS1 DHX36 DHX36 SP1 SP1 UPF3B UPF3B IGF2BP1 IGF2BP1 BARHL2 BARHL2 IMPACT IMPACT LOC102734294 LOC102734294 LOC102745703 LOC102745703 LARP1B LARP1B CYR61 CYR61 KHDRBS1 KHDRBS1 ELAVL1 ELAVL1 LOC102750440 LOC102750440 YTHDF3 YTHDF3 CDK5RAP1 CDK5RAP1 SLC2A13 SLC2A13 DNAJC3 DNAJC3 POLDIP3 POLDIP3 FXR1 FXR1 POLR2G POLR2G MIEF1 MIEF1 PAIP1 PAIP1 TRMT10C TRMT10C SYNCRIP SYNCRIP LOC102732823 LOC102732823 LOC102750290 LOC102750290 NCK1 NCK1 MIF4GD MIF4GD BOLL BOLL LRRTM3 LRRTM3 RPS6KB1 RPS6KB1 IFNG IFNG RPUSD3 RPUSD3 PCIF1 PCIF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FAM46BProtein FAM46B. (427 aa)
FXR2Fragile X mental retardation syndrome-related protein 2. (600 aa)
EIF5AEukaryotic translation initiation factor 5A-1 isoform X1. (184 aa)
UHMK1Serine/threonine-protein kinase Kist. (233 aa)
EEF2Elongation factor 2. (858 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
RBM3Glycine-rich RNA-binding protein 4, mitochondrial isoform X2. (156 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial. (488 aa)
LOC102732056Cytochrome c oxidase assembly protein 3 homolog, mitochondrial-like. (106 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U isoform X1. (825 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa)
DDX3XATP-dependent RNA helicase DDX3X-like isoform X1; Belongs to the DEAD box helicase family. (662 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1-like. (1415 aa)
LOC102730635ATP-dependent RNA helicase DHX29-like. (196 aa)
LOC102729145Eukaryotic translation initiation factor 4 gamma 1-like. (207 aa)
EIF5A2Eukaryotic translation initiation factor 5A. (153 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
LOC102741681Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (445 aa)
RMND1Required for meiotic nuclear division protein 1 homolog. (452 aa)
LARP4La-related protein 4 isoform X1. (444 aa)
EFNA1ephrin-A1 isoform X1; Belongs to the ephrin family. (205 aa)
METTL5Methyltransferase-like protein 5 isoform X2. (209 aa)
BCL3B-cell lymphoma 3 protein. (407 aa)
PIWIL2Piwi-like protein 2; Belongs to the argonaute family. (970 aa)
LOC102738532La-related protein 4B-like. (734 aa)
NCK2Cytoplasmic protein. (380 aa)
LOC102738254Vimentin-like; Belongs to the intermediate filament family. (209 aa)
DHX9ATP-dependent RNA helicase A. (1276 aa)
WIBGPartner of Y14 and mago. (203 aa)
TARBP2RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] (366 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (845 aa)
GSK3AGlycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (419 aa)
LOC102728198YTH domain family protein 1-like isoform X1. (509 aa)
KRT17Keratin, type I cytoskeletal 17; Belongs to the intermediate filament family. (436 aa)
NFE2L2Nuclear factor erythroid 2-related factor 2 isoform X1. (590 aa)
MPV17L2Mpv17-like protein 2 isoform X1; Belongs to the peroxisomal membrane protein PXMP2/4 family. (206 aa)
EIF3DEukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...] (451 aa)
SPHK2Sphingosine kinase 2 isoform X1. (656 aa)
NGRNNeugrin. (294 aa)
FMR1Fragile X mental retardation protein 1-like isoform X2. (547 aa)
CASP3Caspase-3; Belongs to the peptidase C14A family. (302 aa)
ZCCHC4Zinc finger CCHC domain-containing protein 4 isoform X1. (513 aa)
METTL14Methyltransferase-like protein 14; Belongs to the MT-A70-like family. (456 aa)
LOC102732107Ubiquinol-cytochrome-c reductase complex assembly factor 2-like. (136 aa)
UCNUrocortin. (126 aa)
EPHA4Ephrin type-A receptor 4-like isoform X2. (949 aa)
LARP6La-related protein 6. (308 aa)
LOC102737030Receptor tyrosine-protein kinase erbB-2-like; Belongs to the protein kinase superfamily. Tyr protein kinase family. (627 aa)
USP16Ubiquitin carboxyl-terminal hydrolase 16; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. (825 aa)
EIF2S3Eukaryotic translation initiation factor 2 subunit 3 isoform X1. (472 aa)
RPS940S ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. (194 aa)
CNBPCellular nucleic acid-binding protein isoform X1. (177 aa)
NOD2Nucleotide-binding oligomerization domain-containing protein 2. (1013 aa)
DAZLDeleted in azoospermia-like. (302 aa)
THBS1Thrombospondin-1 isoform X1. (1170 aa)
DHX36Probable ATP-dependent RNA helicase DHX36 isoform X1. (1011 aa)
SP1Transcription factor Sp1 isoform X1. (786 aa)
UPF3BRegulator of nonsense transcripts 3B isoform X1. (485 aa)
IGF2BP1Insulin-like growth factor 2 mRNA-binding protein 1 isoform X1. (577 aa)
BARHL2barH-like 2 homeobox protein-like. (382 aa)
IMPACTProtein IMPACT isoform X1. (318 aa)
LOC102734294Protein Tob1-like isoform X1. (336 aa)
LOC102745703Pyruvate kinase; Belongs to the pyruvate kinase family. (610 aa)
LARP1BLa-related protein 1B isoform X2. (335 aa)
CYR61Protein CYR61. (382 aa)
KHDRBS1KH domain-containing, RNA-binding, signal transduction-associated protein 1 isoform X1. (443 aa)
ELAVL1ELAV-like protein; Belongs to the RRM elav family. (326 aa)
LOC102750440Cellular nucleic acid-binding protein-like. (171 aa)
YTHDF3YTH domain family protein 3-like isoform X1. (531 aa)
CDK5RAP1CDK5 regulatory subunit-associated protein 1 isoform X1. (583 aa)
SLC2A13Proton myo-inositol cotransporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (646 aa)
DNAJC3dnaJ homolog subfamily C member 3. (504 aa)
POLDIP3Polymerase delta-interacting protein 3. (378 aa)
FXR1Fragile X mental retardation syndrome-related protein 1 isoform X1. (677 aa)
POLR2GDNA-directed RNA polymerase II subunit RPB7. (172 aa)
MIEF1Mitochondrial dynamics protein MID51. (463 aa)
PAIP1Polyadenylate-binding protein-interacting protein 1 isoform X1. (367 aa)
TRMT10CMitochondrial ribonuclease P protein 1. (423 aa)
SYNCRIPHeterogeneous nuclear ribonucleoprotein Q isoform X1. (623 aa)
LOC102732823Vimentin-like isoform X1; Belongs to the intermediate filament family. (466 aa)
LOC102750290Polyadenylate-binding protein 1-like. (311 aa)
NCK1Cytoplasmic protein. (377 aa)
MIF4GDMIF4G domain-containing protein. (224 aa)
BOLLProtein boule-like isoform X1. (293 aa)
LRRTM3Leucine-rich repeat transmembrane neuronal protein 3 isoform X1. (513 aa)
RPS6KB1Non-specific serine/threonine protein kinase. (445 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
RPUSD3RNA pseudouridylate synthase domain-containing protein 3. (344 aa)
PCIF1Phosphorylated CTD-interacting factor 1. (731 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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