node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FLT3LG | KITLG | A0A2U3Z004 | A0A2U3Y5X8 | Fms-related tyrosine kinase 3 ligand. | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. | 0.655 |
FLT3LG | LOC102742177 | A0A2U3Z004 | A0A2U3Z7D6 | Fms-related tyrosine kinase 3 ligand. | Mast/stem cell growth factor receptor Kit-like. | 0.888 |
FLT3LG | MED1 | A0A2U3Z004 | A0A2U3YTF7 | Fms-related tyrosine kinase 3 ligand. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.975 |
GATA1 | GATA3 | A0A2U3Y495 | A0A2U3YCA3 | Erythroid transcription factor. | Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. | 0.425 |
GATA1 | KITLG | A0A2U3Y495 | A0A2U3Y5X8 | Erythroid transcription factor. | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. | 0.507 |
GATA3 | GATA1 | A0A2U3YCA3 | A0A2U3Y495 | Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. | Erythroid transcription factor. | 0.425 |
KITLG | FLT3LG | A0A2U3Y5X8 | A0A2U3Z004 | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. | Fms-related tyrosine kinase 3 ligand. | 0.655 |
KITLG | GATA1 | A0A2U3Y5X8 | A0A2U3Y495 | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. | Erythroid transcription factor. | 0.507 |
KITLG | LOC102742177 | A0A2U3Y5X8 | A0A2U3Z7D6 | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. | Mast/stem cell growth factor receptor Kit-like. | 0.999 |
LOC102742177 | FLT3LG | A0A2U3Z7D6 | A0A2U3Z004 | Mast/stem cell growth factor receptor Kit-like. | Fms-related tyrosine kinase 3 ligand. | 0.888 |
LOC102742177 | KITLG | A0A2U3Z7D6 | A0A2U3Y5X8 | Mast/stem cell growth factor receptor Kit-like. | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. | 0.999 |
MED1 | FLT3LG | A0A2U3YTF7 | A0A2U3Z004 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Fms-related tyrosine kinase 3 ligand. | 0.975 |
STK3 | STK4 | A0A2U3XFR8 | A0A2U3XV34 | Serine/threonine-protein kinase 3 isoform X1. | Serine/threonine-protein kinase 4. | 0.898 |
STK4 | STK3 | A0A2U3XV34 | A0A2U3XFR8 | Serine/threonine-protein kinase 4. | Serine/threonine-protein kinase 3 isoform X1. | 0.898 |