STRINGSTRING
TMEM38B TMEM38B LOC102740025 LOC102740025 IL7 IL7 FGF9 FGF9 ECM1 ECM1 UBE3A UBE3A FGF10 FGF10 SMPD3 SMPD3 STK3 STK3 ARX ARX SAV1 SAV1 PTEN PTEN GATA6 GATA6 NPPC NPPC DDR2 DDR2 THBS3 THBS3 STK4 STK4 FGF7 FGF7 PTPN11 PTPN11 RARB RARB RAG2 RAG2 ZMPSTE24 ZMPSTE24 OSTN OSTN TGFB2 TGFB2 EHMT2 EHMT2 ADPRHL1 ADPRHL1 ARID2 ARID2 PLAG1 PLAG1 LOC102741200 LOC102741200 LOC102747201 LOC102747201 LOC102737096 LOC102737096 MMP13 MMP13 RARG RARG PRKAR1A PRKAR1A ATF2 ATF2 IFT80 IFT80 SMAD1 SMAD1 CER1 CER1 DLL1 DLL1 LOC102736400 LOC102736400 LOC102727345 LOC102727345 HLX HLX YAP1 YAP1 TENM4 TENM4 LEP LEP JARID2 JARID2 COMP COMP ANXA6 ANXA6 LOC102742062 LOC102742062 LOC102733272 LOC102733272
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TMEM38BTrimeric intracellular cation channel type B. (291 aa)
LOC102740025Protein sprouty homolog 2-like isoform X1. (315 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (158 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ECM1LOW QUALITY PROTEIN: extracellular matrix protein 1. (550 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (876 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa)
SMPD3Sphingomyelin phosphodiesterase 3 isoform X1. (653 aa)
STK3Serine/threonine-protein kinase 3 isoform X1. (491 aa)
ARXHomeobox protein ARX. (457 aa)
SAV1Protein salvador homolog 1. (384 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
GATA6Transcription factor GATA-6. (287 aa)
NPPCC-type natriuretic peptide isoform X1. (126 aa)
DDR2Discoidin domain-containing receptor 2-like. (367 aa)
THBS3Thrombospondin-3 isoform X1. (956 aa)
STK4Serine/threonine-protein kinase 4. (487 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
RARBRetinoic acid receptor beta. (172 aa)
RAG2V(D)J recombination-activating protein 2. (527 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
OSTNOsteocrin. (132 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
EHMT2Histone-lysine N-methyltransferase EHMT2 isoform X1. (1268 aa)
ADPRHL1[Protein ADP-ribosylarginine] hydrolase-like protein 1. (272 aa)
ARID2AT-rich interactive domain-containing protein 2. (1836 aa)
PLAG1Zinc finger protein PLAG1 isoform X1. (499 aa)
LOC102741200Exostosin-1-like; Belongs to the glycosyltransferase 47 family. (746 aa)
LOC102747201Deleted in autism protein 1. (430 aa)
LOC102737096Retinoic acid receptor beta-like. (262 aa)
MMP13Collagenase 3. (470 aa)
RARGRetinoic acid receptor gamma isoform X1. (486 aa)
PRKAR1AcAMP-dependent protein kinase type I-alpha regulatory subunit. (381 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X2. (505 aa)
IFT80Intraflagellar transport protein 80 homolog. (777 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
CER1Cerberus. (274 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (724 aa)
LOC102736400Ellis-van Creveld syndrome protein-like. (192 aa)
LOC102727345Transcription factor SOX-9-like. (282 aa)
HLXH2.0-like homeobox protein. (415 aa)
YAP1Yorkie homolog. (326 aa)
TENM4Teneurin-4. (1083 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (166 aa)
JARID2Protein Jumonji. (1075 aa)
COMPCartilage oligomeric matrix protein. (728 aa)
ANXA6Annexin. (673 aa)
LOC102742062T-box transcription factor TBX5-like. (308 aa)
LOC102733272Cartilage matrix protein-like. (279 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
Server load: low (14%) [HD]