(16 nodes) Positive regulation of mitochondrial membrane permeability network (Leptonychotes weddellii)

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Your Input:
	VDAC2	Voltage-dependent anion-selective channel protein 2 isoform X1. (294 aa)
	GSK3A	Glycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (419 aa)
	BOK	Bcl-2-related ovarian killer protein. (213 aa)
	LOC102736150	Paraplegin-like. (200 aa)
	HEBP2	Heme-binding protein 2. (150 aa)
	LOC102746004	Bcl-2-like protein 11-like isoform X2. (140 aa)
	EYA2	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (251 aa)
	STPG1	O(6)-methylguanine-induced apoptosis 2. (335 aa)
	ZNF205	Zinc finger protein 205 isoform X1. (552 aa)
	ATF2	Cyclic AMP-dependent transcription factor ATF-2 isoform X2. (505 aa)
	LOC102745784	Mitochondrial Rho GTPase 1-like. (495 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
	PPIF	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (210 aa)
	LOC102726691	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform X2. (194 aa)
	LOC102742246	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like. (149 aa)
	SPG7	Paraplegin. (607 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF2	GSK3A	A0A2U3YEN6	A0A2U3Z2W3	Cyclic AMP-dependent transcription factor ATF-2 isoform X2.	Glycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily.	0.476
BOK	LOC102726691	A0A2U3Z482	A0A2U3XL53	Bcl-2-related ovarian killer protein.	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform X2.	0.549
BOK	LOC102742246	A0A2U3Z482	A0A2U3XCQ1	Bcl-2-related ovarian killer protein.	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like.	0.474
BOK	LOC102746004	A0A2U3Z482	A0A2U3YHX1	Bcl-2-related ovarian killer protein.	Bcl-2-like protein 11-like isoform X2.	0.814
GSK3A	ATF2	A0A2U3Z2W3	A0A2U3YEN6	Glycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily.	Cyclic AMP-dependent transcription factor ATF-2 isoform X2.	0.476
GSK3A	TP53	A0A2U3Z2W3	A0A2U3Y5G3	Glycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.413
LOC102726691	BOK	A0A2U3XL53	A0A2U3Z482	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform X2.	Bcl-2-related ovarian killer protein.	0.549
LOC102726691	LOC102742246	A0A2U3XL53	A0A2U3XCQ1	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform X2.	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like.	0.789
LOC102726691	TP53	A0A2U3XL53	A0A2U3Y5G3	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform X2.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.503
LOC102736150	PPIF	A0A2U3Z776	A0A2U3XUA6	Paraplegin-like.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.483
LOC102736150	SPG7	A0A2U3Z776	A0A2U3YNN3	Paraplegin-like.	Paraplegin.	0.948
LOC102742246	BOK	A0A2U3XCQ1	A0A2U3Z482	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like.	Bcl-2-related ovarian killer protein.	0.474
LOC102742246	LOC102726691	A0A2U3XCQ1	A0A2U3XL53	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like.	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform X2.	0.789
LOC102745784	VDAC2	A0A2U3Y638	A0A2U3Z1R3	Mitochondrial Rho GTPase 1-like.	Voltage-dependent anion-selective channel protein 2 isoform X1.	0.476
LOC102746004	BOK	A0A2U3YHX1	A0A2U3Z482	Bcl-2-like protein 11-like isoform X2.	Bcl-2-related ovarian killer protein.	0.814
LOC102746004	TP53	A0A2U3YHX1	A0A2U3Y5G3	Bcl-2-like protein 11-like isoform X2.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.401
PPIF	LOC102736150	A0A2U3XUA6	A0A2U3Z776	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	Paraplegin-like.	0.483
PPIF	SPG7	A0A2U3XUA6	A0A2U3YNN3	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	Paraplegin.	0.483
PPIF	TP53	A0A2U3XUA6	A0A2U3Y5G3	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.522
PPIF	VDAC2	A0A2U3XUA6	A0A2U3Z1R3	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	Voltage-dependent anion-selective channel protein 2 isoform X1.	0.935