(11 nodes) Aorta morphogenesis network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FOXH1	Forkhead box protein H1. (360 aa)
	SEC24B	Protein transport protein Sec24B isoform X1. (1258 aa)
	CHD7	chromodomain-helicase-DNA-binding protein 7. (2429 aa)
	SRF	Serum response factor. (508 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
	BMPR1A	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
	DLL4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
	ACVRL1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
	EYA1	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
	FKBP10	Peptidylprolyl isomerase. (582 aa)
	LOC102731463	Transcription factor AP-2-beta-like. (180 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACVRL1	BMPR1A	A0A2U3YIM9	A0A2U3Y9P6	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.619
BMPR1A	ACVRL1	A0A2U3Y9P6	A0A2U3YIM9	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.619
DLL4	JAG1	A0A2U3YFQ8	A0A2U3XZY3	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.451
EYA1	JAG1	A0A2U3YJ16	A0A2U3XZY3	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.493
JAG1	DLL4	A0A2U3XZY3	A0A2U3YFQ8	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.451
JAG1	EYA1	A0A2U3XZY3	A0A2U3YJ16	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.493