STRINGSTRING
CHD7 CHD7 POU1F1 POU1F1 TSHR TSHR PLS1 PLS1 NIPBL NIPBL LOC102731864 LOC102731864 LOC102741867 LOC102741867 STAT5A STAT5A LOC102738856 LOC102738856 CELF1 CELF1 BBS2 BBS2 VIL1 VIL1 LOC102747249 LOC102747249 LOC102748609 LOC102748609 CSF1 CSF1 VILL VILL STAT5B STAT5B PEX5 PEX5 LOC102742298 LOC102742298 PPIB PPIB GHRH GHRH GHSR GHSR CREB1 CREB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHD7chromodomain-helicase-DNA-binding protein 7. (2429 aa)
POU1F1POU domain protein. (317 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
PLS1Plastin-1. (604 aa)
NIPBLNipped-B protein. (2803 aa)
LOC102731864Signal transducer and activator of transcription 5B-like. (353 aa)
LOC102741867Villin-1-like. (505 aa)
STAT5ASignal transducer and activator of transcription 5A. (464 aa)
LOC102738856Villin-like protein-like. (205 aa)
CELF1CUGBP Elav-like family member 1 isoform X2. (485 aa)
BBS2Bardet-Biedl syndrome 2 protein-like. (603 aa)
VIL1Villin-1. (330 aa)
LOC102747249Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (271 aa)
LOC102748609Sodium-dependent dopamine transporter-like. (364 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (547 aa)
VILLVillin-like protein-like. (375 aa)
STAT5BSignal transducer and activator of transcription 5B. (508 aa)
PEX5Peroxisomal targeting signal 1 receptor-like. (349 aa)
LOC102742298Peroxisomal targeting signal 1 receptor-like. (323 aa)
PPIBPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
GHRHSomatoliberin. (106 aa)
GHSRGrowth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family. (366 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
Server load: low (24%) [HD]