(10 nodes) Muscle cell fate commitment network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa)
	MEF2C	Myocyte-specific enhancer factor 2C-like isoform X2. (473 aa)
	VWA5A	Von Willebrand factor A domain-containing protein 5A-like. (784 aa)
	TBX3	T-box transcription factor TBX3. (675 aa)
	VWA5B2	Von Willebrand factor A domain-containing protein 5B2. (1251 aa)
	WNT8A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
	MYL2	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform isoform X1. (166 aa)
	PRADC1	Protease-associated domain-containing protein 1. (188 aa)
	LOC102742062	T-box transcription factor TBX5-like. (308 aa)
	LOC102747941	Von Willebrand factor A domain-containing protein 5B1-like. (642 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102742062	MEF2C	A0A2U3Z3X1	A0A2U3YMC3	T-box transcription factor TBX5-like.	Myocyte-specific enhancer factor 2C-like isoform X2.	0.715
LOC102742062	MYL2	A0A2U3Z3X1	A0A2U3Y006	T-box transcription factor TBX5-like.	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform isoform X1.	0.547
LOC102747941	VWA5A	A0A2U3Z559	A0A2U3YER2	Von Willebrand factor A domain-containing protein 5B1-like.	Von Willebrand factor A domain-containing protein 5A-like.	0.561
MEF2C	LOC102742062	A0A2U3YMC3	A0A2U3Z3X1	Myocyte-specific enhancer factor 2C-like isoform X2.	T-box transcription factor TBX5-like.	0.715
MEF2C	MYL2	A0A2U3YMC3	A0A2U3Y006	Myocyte-specific enhancer factor 2C-like isoform X2.	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform isoform X1.	0.513
MYL2	LOC102742062	A0A2U3Y006	A0A2U3Z3X1	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform isoform X1.	T-box transcription factor TBX5-like.	0.547
MYL2	MEF2C	A0A2U3Y006	A0A2U3YMC3	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform isoform X1.	Myocyte-specific enhancer factor 2C-like isoform X2.	0.513
VWA5A	LOC102747941	A0A2U3YER2	A0A2U3Z559	Von Willebrand factor A domain-containing protein 5A-like.	Von Willebrand factor A domain-containing protein 5B1-like.	0.561