33 items (Leptonychotes weddellii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	JADE2	Protein Jade-2 isoform X2. (784 aa)
	LOC102746722	Germinal-center associated nuclear protein-like. (323 aa)
	LOC102728667	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (101 aa)
	TAF4	Transcription initiation factor TFIID subunit 4. (668 aa)
	TADA1	Transcriptional adapter 1. (335 aa)
	MBIP	MAP3K12-binding inhibitory protein 1 isoform X1. (344 aa)
	TAF12	Transcription initiation factor TFIID subunit 12 isoform X1. (161 aa)
	BRPF1	Peregrin isoform X1. (1220 aa)
	TADA3	Transcriptional adapter 3 isoform X1. (432 aa)
	ATXN7L3	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (354 aa)
	KAT2A	Histone acetyltransferase KAT2A isoform X2. (838 aa)
	ING4	Inhibitor of growth protein. (249 aa)
	BRPF3	Bromodomain and PHD finger-containing protein 3 isoform X1. (1207 aa)
	ATXN7L1	Ataxin-7-like protein 1 isoform X1. (857 aa)
	POLE3	DNA polymerase epsilon subunit 3. (147 aa)
	SUPT3H	Transcription initiation protein SPT3 homolog. (377 aa)
	LOC102726171	LIM domain-binding protein 1-like. (190 aa)
	KAT2B	Histone acetyltransferase KAT2B. (735 aa)
	EP300	Histone acetyltransferase p300. (2425 aa)
	LEF1	Lymphoid enhancer-binding factor 1 isoform X1. (399 aa)
	JADE1	Protein Jade-1 isoform X1. (843 aa)
	DR1	Protein Dr1 isoform X1. (175 aa)
	BRCA2	Breast cancer type 2 susceptibility protein homolog. (2818 aa)
	KAT8	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (458 aa)
	IRF4	Interferon regulatory factor 4 isoform X1. (451 aa)
	TAF6	Transcription initiation factor TFIID subunit 6 isoform X1. (677 aa)
	JADE3	Protein Jade-3. (823 aa)
	LOC102732851	LIM domain-binding protein 1-like. (227 aa)
	KAT7	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)
	LOC102729806	WD repeat-containing protein 5-like. (334 aa)
	ATXN7L2	Ataxin-7-like protein 2 isoform X2. (701 aa)
	ATXN7	Ataxin-7. (650 aa)
	MYOD1	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATXN7	ATXN7L3	A0A2U3Z4V9	A0A2U3Y558	Ataxin-7.	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	0.956
ATXN7	KAT2A	A0A2U3Z4V9	A0A2U3Y4H3	Ataxin-7.	Histone acetyltransferase KAT2A isoform X2.	0.964
ATXN7	KAT2B	A0A2U3Z4V9	A0A2U3XFC4	Ataxin-7.	Histone acetyltransferase KAT2B.	0.842
ATXN7	LOC102728667	A0A2U3Z4V9	A0A2U3YM17	Ataxin-7.	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...]	0.962
ATXN7	SUPT3H	A0A2U3Z4V9	A0A2U3XSU2	Ataxin-7.	Transcription initiation protein SPT3 homolog.	0.915
ATXN7	TADA1	A0A2U3Z4V9	A0A2U3YC50	Ataxin-7.	Transcriptional adapter 1.	0.771
ATXN7	TADA3	A0A2U3Z4V9	A0A2U3Y5R5	Ataxin-7.	Transcriptional adapter 3 isoform X1.	0.975
ATXN7	TAF12	A0A2U3Z4V9	A0A2U3Y8A6	Ataxin-7.	Transcription initiation factor TFIID subunit 12 isoform X1.	0.936
ATXN7	TAF6	A0A2U3Z4V9	A0A2U3XQX4	Ataxin-7.	Transcription initiation factor TFIID subunit 6 isoform X1.	0.846
ATXN7L1	ATXN7L3	A0A2U3XX66	A0A2U3Y558	Ataxin-7-like protein 1 isoform X1.	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	0.890
ATXN7L1	KAT2A	A0A2U3XX66	A0A2U3Y4H3	Ataxin-7-like protein 1 isoform X1.	Histone acetyltransferase KAT2A isoform X2.	0.822
ATXN7L1	KAT2B	A0A2U3XX66	A0A2U3XFC4	Ataxin-7-like protein 1 isoform X1.	Histone acetyltransferase KAT2B.	0.822
ATXN7L1	LOC102728667	A0A2U3XX66	A0A2U3YM17	Ataxin-7-like protein 1 isoform X1.	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...]	0.866
ATXN7L1	SUPT3H	A0A2U3XX66	A0A2U3XSU2	Ataxin-7-like protein 1 isoform X1.	Transcription initiation protein SPT3 homolog.	0.837
ATXN7L1	TADA1	A0A2U3XX66	A0A2U3YC50	Ataxin-7-like protein 1 isoform X1.	Transcriptional adapter 1.	0.544
ATXN7L1	TADA3	A0A2U3XX66	A0A2U3Y5R5	Ataxin-7-like protein 1 isoform X1.	Transcriptional adapter 3 isoform X1.	0.890
ATXN7L1	TAF12	A0A2U3XX66	A0A2U3Y8A6	Ataxin-7-like protein 1 isoform X1.	Transcription initiation factor TFIID subunit 12 isoform X1.	0.860
ATXN7L1	TAF4	A0A2U3XX66	A0A2U3YLT4	Ataxin-7-like protein 1 isoform X1.	Transcription initiation factor TFIID subunit 4.	0.607
ATXN7L1	TAF6	A0A2U3XX66	A0A2U3XQX4	Ataxin-7-like protein 1 isoform X1.	Transcription initiation factor TFIID subunit 6 isoform X1.	0.846
ATXN7L2	ATXN7L3	A0A2U3Z1A6	A0A2U3Y558	Ataxin-7-like protein 2 isoform X2.	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	0.927