(36 nodes) Regulation of vacuole organization network (Leptonychotes weddellii)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	LOC102732749	Lysosomal-associated transmembrane protein 4A-like. (197 aa)
	TREX1	Three prime repair exonuclease 1. (314 aa)
	LOC102726984	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha-like. (135 aa)
	SMCR8	smith-Magenis syndrome chromosomal region candidate gene 8 protein. (937 aa)
	LOC102749117	Sorting nexin. (624 aa)
	SNX30	Sorting nexin-30. (437 aa)
	RAB3GAP2	Rab3 GTPase-activating protein non-catalytic subunit isoform X1. (1393 aa)
	LOC102729166	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like. (134 aa)
	PIP4K2B	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta. (416 aa)
	LOC102730059	TBC1 domain family member 14-like. (241 aa)
	LAPTM4B	Lysosomal-associated transmembrane protein 4B. (226 aa)
	KIAA1324	UPF0577 protein KIAA1324 homolog. (926 aa)
	WIPI1	WD repeat domain phosphoinositide-interacting protein 1 isoform X1. (446 aa)
	LOC102740301	Fasciculation and elongation protein zeta-1-like. (247 aa)
	PIP4K2C	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma. (220 aa)
	SH3GLB1	endophilin-B1 isoform X1. (393 aa)
	LOC102735189	Intraflagellar transport protein 20 homolog. (115 aa)
	PHF23	PHD finger protein 23 isoform X1. (403 aa)
	ADPRHL1	[Protein ADP-ribosylarginine] hydrolase-like protein 1. (272 aa)
	CHMP4A	LOW QUALITY PROTEIN: charged multivesicular body protein 4a. (265 aa)
	EHMT2	Histone-lysine N-methyltransferase EHMT2 isoform X1. (1268 aa)
	WDR45	WD repeat domain phosphoinositide-interacting protein 4 isoform X1. (361 aa)
	PINK1	Serine/threonine-protein kinase PINK1, mitochondrial. (488 aa)
	FEZ2	Fasciculation and elongation protein zeta-2. (297 aa)
	LOC102739096	Protein C9orf72 homolog. (235 aa)
	RNF5	E3 ubiquitin-protein ligase RNF5. (180 aa)
	LOC102748670	Lysosomal-associated transmembrane protein 4A-like. (233 aa)
	TBC1D12	TBC1 domain family member 12. (774 aa)
	TMEM39B	Transmembrane protein 39B. (492 aa)
	NUPR1	Nuclear protein 1 isoform X1. (82 aa)
	LOC102730419	Fasciculation and elongation protein zeta-1-like. (104 aa)
	TMEM39A	Transmembrane protein 39A. (488 aa)
	SCFD1	Sec1 family domain-containing protein 1 isoform X1; Belongs to the STXBP/unc-18/SEC1 family. (641 aa)
	LRRK2	Leucine-rich repeat serine/threonine-protein kinase 2. (2150 aa)
	LOC102738981	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like. (143 aa)
	LOC102733070	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like. (117 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LAPTM4B	LOC102732749	A0A2U3YGB6	A0A2U3Z4K8	Lysosomal-associated transmembrane protein 4B.	Lysosomal-associated transmembrane protein 4A-like.	0.544
LAPTM4B	LOC102748670	A0A2U3YGB6	A0A2U3XWA3	Lysosomal-associated transmembrane protein 4B.	Lysosomal-associated transmembrane protein 4A-like.	0.540
LOC102726984	LOC102729166	A0A2U3Z2V4	A0A2U3YMI2	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha-like.	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like.	0.890
LOC102726984	LOC102733070	A0A2U3Z2V4	A0A2U3Z8L6	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha-like.	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like.	0.890
LOC102726984	LOC102738981	A0A2U3Z2V4	A0A2U3Z8R9	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha-like.	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like.	0.888
LOC102726984	PIP4K2B	A0A2U3Z2V4	A0A2U3YI20	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha-like.	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta.	0.983
LOC102726984	PIP4K2C	A0A2U3Z2V4	A0A2U3Y8S9	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha-like.	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma.	0.987
LOC102729166	LOC102726984	A0A2U3YMI2	A0A2U3Z2V4	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like.	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha-like.	0.890
LOC102729166	LOC102738981	A0A2U3YMI2	A0A2U3Z8R9	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like.	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like.	0.663
LOC102729166	PIP4K2B	A0A2U3YMI2	A0A2U3YI20	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like.	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta.	0.873
LOC102729166	PIP4K2C	A0A2U3YMI2	A0A2U3Y8S9	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like.	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma.	0.900
LOC102730059	LOC102749117	A0A2U3YI03	A0A2U3YXZ4	TBC1 domain family member 14-like.	Sorting nexin.	0.487
LOC102730059	TBC1D12	A0A2U3YI03	A0A2U3XW10	TBC1 domain family member 14-like.	TBC1 domain family member 12.	0.900
LOC102730419	LOC102740301	A0A2U3XIS1	A0A2U3Y9D3	Fasciculation and elongation protein zeta-1-like.	Fasciculation and elongation protein zeta-1-like.	0.900
LOC102732749	LAPTM4B	A0A2U3Z4K8	A0A2U3YGB6	Lysosomal-associated transmembrane protein 4A-like.	Lysosomal-associated transmembrane protein 4B.	0.544
LOC102733070	LOC102726984	A0A2U3Z8L6	A0A2U3Z2V4	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like.	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha-like.	0.890
LOC102733070	LOC102738981	A0A2U3Z8L6	A0A2U3Z8R9	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like.	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like.	0.816
LOC102733070	PIP4K2B	A0A2U3Z8L6	A0A2U3YI20	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like.	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta.	0.873
LOC102733070	PIP4K2C	A0A2U3Z8L6	A0A2U3Y8S9	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like.	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma.	0.900
LOC102738981	LOC102726984	A0A2U3Z8R9	A0A2U3Z2V4	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like.	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha-like.	0.888