(12 nodes) Autophagy of nucleus network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	WIPI1	WD repeat domain phosphoinositide-interacting protein 1 isoform X1. (446 aa)
	LOC102743442	Autophagy-related protein 3. (314 aa)
	RB1CC1	RB1-inducible coiled-coil protein 1 isoform X1. (1593 aa)
	ATG2B	Autophagy-related protein 2 homolog B. (1878 aa)
	ATG12	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
	WDR45	WD repeat domain phosphoinositide-interacting protein 4 isoform X1. (361 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (255 aa)
	ATG9A	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (743 aa)
	WDR45B	WD repeat domain phosphoinositide-interacting protein 3. (344 aa)
	LOC102735948	Autophagy-related protein 13-like. (287 aa)
	LOC102744509	Autophagy protein 5-like. (78 aa)
	LOC102740574	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (400 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG12	ATG2B	A0A2U3XZP0	A0A2U3XWK7	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy-related protein 2 homolog B.	0.570
ATG12	ATG5	A0A2U3XZP0	A0A2U3Y6R5	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG12	ATG9A	A0A2U3XZP0	A0A2U3Y7P8	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.739
ATG12	LOC102735948	A0A2U3XZP0	A0A2U3Z6I2	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy-related protein 13-like.	0.699
ATG12	LOC102740574	A0A2U3XZP0	A0A2U3Z7N7	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.582
ATG12	LOC102743442	A0A2U3XZP0	A0A2U3X834	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy-related protein 3.	0.999
ATG12	LOC102744509	A0A2U3XZP0	A0A2U3Z6M9	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy protein 5-like.	0.952
ATG12	RB1CC1	A0A2U3XZP0	A0A2U3XSW8	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	RB1-inducible coiled-coil protein 1 isoform X1.	0.610
ATG12	WDR45	A0A2U3XZP0	A0A2U3Y407	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	WD repeat domain phosphoinositide-interacting protein 4 isoform X1.	0.423
ATG12	WIPI1	A0A2U3XZP0	A0A2U3YDZ9	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	WD repeat domain phosphoinositide-interacting protein 1 isoform X1.	0.933
ATG2B	ATG12	A0A2U3XWK7	A0A2U3XZP0	Autophagy-related protein 2 homolog B.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.570
ATG2B	ATG5	A0A2U3XWK7	A0A2U3Y6R5	Autophagy-related protein 2 homolog B.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.593
ATG2B	ATG9A	A0A2U3XWK7	A0A2U3Y7P8	Autophagy-related protein 2 homolog B.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.869
ATG2B	LOC102735948	A0A2U3XWK7	A0A2U3Z6I2	Autophagy-related protein 2 homolog B.	Autophagy-related protein 13-like.	0.505
ATG2B	LOC102740574	A0A2U3XWK7	A0A2U3Z7N7	Autophagy-related protein 2 homolog B.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.831
ATG2B	LOC102743442	A0A2U3XWK7	A0A2U3X834	Autophagy-related protein 2 homolog B.	Autophagy-related protein 3.	0.493
ATG2B	RB1CC1	A0A2U3XWK7	A0A2U3XSW8	Autophagy-related protein 2 homolog B.	RB1-inducible coiled-coil protein 1 isoform X1.	0.665
ATG2B	WDR45	A0A2U3XWK7	A0A2U3Y407	Autophagy-related protein 2 homolog B.	WD repeat domain phosphoinositide-interacting protein 4 isoform X1.	0.699
ATG2B	WDR45B	A0A2U3XWK7	A0A2U3YA16	Autophagy-related protein 2 homolog B.	WD repeat domain phosphoinositide-interacting protein 3.	0.601
ATG2B	WIPI1	A0A2U3XWK7	A0A2U3YDZ9	Autophagy-related protein 2 homolog B.	WD repeat domain phosphoinositide-interacting protein 1 isoform X1.	0.993