STRINGSTRING
CA2 CA2 SLC7A11 SLC7A11 ATP6V0D2 ATP6V0D2 DUOXA2 DUOXA2 GPR116 GPR116 SLC2A13 SLC2A13 USH2A USH2A GJA1 GJA1 ATP6V1B1 ATP6V1B1 LOC102736213 LOC102736213 LOC102746429 LOC102746429 KHDC3L KHDC3L OOEP OOEP ERBB3 ERBB3 EDAR EDAR AKR1A1 AKR1A1 CFTR CFTR AQP6 AQP6 AQP2 AQP2 CTSB CTSB LOC102727975 LOC102727975 UPK1B UPK1B SLC23A1 SLC23A1 SCNN1G SCNN1G EXOC1 EXOC1 SLC4A2 SLC4A2 SCNN1B SCNN1B NUMB NUMB FRMD6 FRMD6 NIN NIN SNX10 SNX10 SLC46A1 SLC46A1 SLC4A9 SLC4A9 LOC102746853 LOC102746853 PARD6B PARD6B HOMER1 HOMER1 CEACAM20 CEACAM20 PLAUR PLAUR SLC4A11 SLC4A11 PRKCZ PRKCZ PPAP2A PPAP2A CLDND1 CLDND1 PTEN PTEN DRAM2 DRAM2 SLC34A1 SLC34A1 SLC22A2 SLC22A2 SLC22A1 SLC22A1 MSN MSN PLET1 PLET1 PTPRO PTPRO CUBN CUBN CRB1 CRB1 LOC102745867 LOC102745867 ITGB3 ITGB3 DDR2 DDR2 EMP2 EMP2 SLC6A4 SLC6A4 MPP5 MPP5 SLC2A5 SLC2A5 SLC22A5 SLC22A5 SHROOM1 SHROOM1 FZD3 FZD3 SLC11A2 SLC11A2 EDA EDA F2RL2 F2RL2 SLC23A2 SLC23A2 LRRC6 LRRC6 CA4 CA4 SLC22A18 SLC22A18 KCNQ1 KCNQ1 AGER AGER PRKCI PRKCI LOC102743194 LOC102743194 LOC102729741 LOC102729741 SLC12A1 SLC12A1 LOC102738400 LOC102738400 JAG1 JAG1 CLIC4 CLIC4 TEK TEK SLC34A2 SLC34A2 SLC19A1 SLC19A1 SLC38A3 SLC38A3 SLC34A3 SLC34A3 LOC102748973 LOC102748973 ATP1B3 ATP1B3 LOC102743402 LOC102743402 CPO CPO PTCH1 PTCH1 SLC44A4 SLC44A4 ATP4B ATP4B LOC102727326 LOC102727326 MARVELD2 MARVELD2 SLC30A5 SLC30A5 ATP1B2 ATP1B2 DVL2 DVL2 OCLN OCLN VASH1 VASH1 ATP6V1A ATP6V1A LOC102733393 LOC102733393 C5AR2 C5AR2 SLC9A1 SLC9A1 RAB18 RAB18 THY1 THY1 ATP1B1 ATP1B1 RAPGEF2 RAPGEF2 CLDN1 CLDN1 SLC16A3 SLC16A3 RHCG RHCG LOC102746703 LOC102746703 SLC24A4 SLC24A4 SLC9A3R2 SLC9A3R2 FAT1 FAT1 STXBP3 STXBP3 LOC102734199 LOC102734199 PSEN2 PSEN2 UPK1A UPK1A CLCN5 CLCN5 KCNE1 KCNE1 PLAT PLAT AMN AMN LDLR LDLR DLL1 DLL1 PDZK1 PDZK1 LOC102743326 LOC102743326 LOC102731813 LOC102731813 LOC102729573 LOC102729573 ANO1 ANO1 DPEP1 DPEP1 LOC102726731 LOC102726731 SLC22A12 SLC22A12 ATP6V1B2 ATP6V1B2 SLC22A11 SLC22A11 SLC12A3 SLC12A3 FOLR1 FOLR1 FOLR2 FOLR2 P2RX2 P2RX2 GP2 GP2 LOC102749897 LOC102749897 SLC39A4 SLC39A4 SLC3A1 SLC3A1 LOC102733028 LOC102733028 LOC102748904 LOC102748904 DYNC2LI1 DYNC2LI1 GIF GIF NEDD1 NEDD1 TMEM114 TMEM114 MAL2 MAL2 LOC102747715 LOC102747715 SLC6A18 SLC6A18 OCEL1 OCEL1 LOC102737538 LOC102737538 LOC102734325 LOC102734325 LOC102734437 LOC102734437 SLC39A14 SLC39A14 SLC46A2 SLC46A2 LOC102746933 LOC102746933 SLC29A1 SLC29A1 AQP1 AQP1 CDHR2 CDHR2 FXYD1 FXYD1 LOC102749114 LOC102749114 LOC102736228 LOC102736228 STX3 STX3 CETN2 CETN2 PARD6A PARD6A UPK2 UPK2 C2CD2L C2CD2L USH1C USH1C LOC102727281 LOC102727281 CCDC23 CCDC23 LOC102738549 LOC102738549 LOC102749234 LOC102749234 RDX RDX SLC29A4 SLC29A4 SLC6A20 SLC6A20 LOC102738369 LOC102738369 KCNK1 KCNK1 LOC102736444 LOC102736444 CIB3 CIB3 LOC102730118 LOC102730118 DUOX2 DUOX2 LOC102726269 LOC102726269 LOC102737868 LOC102737868 SLC7A1 SLC7A1 LOC102726878 LOC102726878 UPK3A UPK3A SPEF1 SPEF1 SLC26A9 SLC26A9 LOC102747652 LOC102747652 TMEM235 TMEM235 ABCG8 ABCG8 SLC5A12 SLC5A12
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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CA2Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (260 aa)
SLC7A11Cystine/glutamate transporter-like isoform X2. (503 aa)
ATP6V0D2V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
DUOXA2Dual oxidase maturation factor 2. (320 aa)
GPR116Probable G-protein coupled receptor 116; Belongs to the G-protein coupled receptor 2 family. (1346 aa)
SLC2A13Proton myo-inositol cotransporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (646 aa)
USH2AUsherin-like. (2873 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
LOC102736213Solute carrier family 12 member 2-like. (641 aa)
LOC102746429Na(+)/H(+) exchange regulatory cofactor NHE-RF1-like. (222 aa)
KHDC3LKHDC3-like protein. (235 aa)
OOEPOocyte-expressed protein. (149 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3. (1339 aa)
EDARTumor necrosis factor receptor superfamily member EDAR. (238 aa)
AKR1A1Alcohol dehydrogenase [NADP(+)]. (332 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1483 aa)
AQP6LOW QUALITY PROTEIN: aquaporin-6; Belongs to the MIP/aquaporin (TC 1.A.8) family. (283 aa)
AQP2Aquaporin-2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
CTSBCathepsin B; Belongs to the peptidase C1 family. (339 aa)
LOC102727975V-type proton ATPase subunit E 1-like isoform X1. (226 aa)
UPK1BUroplakin-1b; Belongs to the tetraspanin (TM4SF) family. (260 aa)
SLC23A1Solute carrier family 23 member 1. (605 aa)
SCNN1GAmiloride-sensitive sodium channel subunit gamma; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (649 aa)
EXOC1Exocyst complex component 1 isoform X1. (894 aa)
SLC4A2Anion exchange protein. (1237 aa)
SCNN1BAmiloride-sensitive sodium channel subunit beta; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (641 aa)
NUMBProtein numb homolog isoform X1. (653 aa)
FRMD6FERM domain-containing protein 6-like isoform X1. (622 aa)
NINNinein isoform X1. (2089 aa)
SNX10Sorting nexin-10. (201 aa)
SLC46A1Proton-coupled folate transporter isoform X1. (459 aa)
SLC4A9Anion exchange protein. (954 aa)
LOC102746853Cytochrome b reductase 1-like. (284 aa)
PARD6BPartitioning defective 6 homolog beta. (370 aa)
HOMER1Homer protein homolog 1 isoform X1. (354 aa)
CEACAM20Carcinoembryonic antigen-related cell adhesion molecule 20. (480 aa)
PLAURUrokinase plasminogen activator surface receptor isoform X1. (335 aa)
SLC4A11Sodium bicarbonate transporter-like protein 11. (875 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (557 aa)
PPAP2ALipid phosphate phosphohydrolase 1 isoform X1. (286 aa)
CLDND1Claudin domain-containing protein 1 isoform X1. (253 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
DRAM2DNA damage-regulated autophagy modulator protein 2 isoform X2. (266 aa)
SLC34A1Sodium-dependent phosphate transport protein 2A. (639 aa)
SLC22A2Solute carrier family 22 member 2. (183 aa)
SLC22A1Solute carrier family 22 member 1. (554 aa)
MSNLOW QUALITY PROTEIN: moesin. (546 aa)
PLET1Placenta-expressed transcript 1 protein. (128 aa)
PTPROReceptor-type tyrosine-protein phosphatase O isoform X1. (1216 aa)
CUBNCubilin. (3065 aa)
CRB1Protein crumbs homolog 1 isoform X1. (1406 aa)
LOC102745867Solute carrier family 22 member 2-like. (318 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (852 aa)
DDR2Discoidin domain-containing receptor 2-like. (367 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
MPP5MAGUK p55 subfamily member 5; Belongs to the MAGUK family. (675 aa)
SLC2A5Solute carrier family 2, facilitated glucose transporter member 5; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (508 aa)
SLC22A5Solute carrier family 22 member 5. (557 aa)
SHROOM1Protein Shroom1. (672 aa)
FZD3Frizzled-3 isoform X2; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
SLC11A2Natural resistance-associated macrophage protein 2 isoform X2. (568 aa)
EDAectodysplasin-A isoform X1; Belongs to the tumor necrosis factor family. (390 aa)
F2RL2Proteinase-activated receptor 3-like. (377 aa)
SLC23A2Solute carrier family 23 member 2. (495 aa)
LRRC6Protein tilB homolog. (274 aa)
CA4Carbonic anhydrase 4; Belongs to the alpha-carbonic anhydrase family. (313 aa)
SLC22A18Solute carrier family 22 member 18. (424 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (599 aa)
AGERAdvanced glycosylation end product-specific receptor. (397 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (543 aa)
LOC102743194V-type proton ATPase subunit d 2-like. (302 aa)
LOC102729741Protein S100; Belongs to the S-100 family. (79 aa)
SLC12A1Solute carrier family 12 member 1 isoform X2. (1100 aa)
LOC102738400Annexin. (345 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
CLIC4Chloride intracellular channel protein 4. (135 aa)
TEKAngiopoietin-1 receptor isoform X1. (1125 aa)
SLC34A2Sodium-dependent phosphate transport protein 2B. (693 aa)
SLC19A1Folate transporter 1. (507 aa)
SLC38A3Sodium-coupled neutral amino acid transporter 3. (468 aa)
SLC34A3Sodium-dependent phosphate transport protein 2C. (602 aa)
LOC102748973Multidrug resistance-associated protein 5-like. (836 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
LOC102743402Annexin. (173 aa)
CPOCarboxypeptidase O. (402 aa)
PTCH1Protein patched homolog 1. (1301 aa)
SLC44A4Choline transporter-like protein 4 isoform X1; Belongs to the CTL (choline transporter-like) family. (709 aa)
ATP4BSodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
LOC102727326Cathepsin L1-like isoform X1; Belongs to the peptidase C1 family. (334 aa)
MARVELD2MARVEL domain-containing protein 2. (559 aa)
SLC30A5Zinc transporter 5. (766 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2 isoform X1. (734 aa)
OCLNOccludin. (271 aa)
VASH1Vasohibin-1. (363 aa)
ATP6V1AV-type proton ATPase catalytic subunit A. (394 aa)
LOC102733393Protein FAM65B-like. (563 aa)
C5AR2C5a anaphylatoxin chemotactic receptor 2. (337 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (817 aa)
RAB18Ras-related protein Rab-18 isoform X1. (206 aa)
THY1Thy-1 membrane glycoprotein. (161 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2 isoform X1. (1499 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
SLC16A3Monocarboxylate transporter 4. (460 aa)
RHCGAmmonium transporter Rh type C; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (460 aa)
LOC102746703Unconventional myosin-Ia-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (619 aa)
SLC24A4Sodium/potassium/calcium exchanger 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (513 aa)
SLC9A3R2Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform X1. (227 aa)
FAT1Protocadherin Fat 1. (4345 aa)
STXBP3Syntaxin-binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (592 aa)
LOC102734199V-type proton ATPase subunit E 1-like. (206 aa)
PSEN2Presenilin-2. (115 aa)
UPK1ATetraspanin. (257 aa)
CLCN5Chloride channel protein. (812 aa)
KCNE1Potassium voltage-gated channel subfamily E member 1 isoform X2. (124 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (560 aa)
AMNProtein amnionless. (476 aa)
LDLRLow-density lipoprotein receptor. (861 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (724 aa)
PDZK1Na(+)/H(+) exchange regulatory cofactor NHE-RF3 isoform X1. (519 aa)
LOC102743326Tumor necrosis factor receptor superfamily member EDAR-like. (298 aa)
LOC102731813Frizzled-6-like; Belongs to the G-protein coupled receptor Fz/Smo family. (400 aa)
LOC102729573Usherin-like. (1546 aa)
ANO1Anoctamin. (978 aa)
DPEP1Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (409 aa)
LOC102726731Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (251 aa)
SLC22A12Solute carrier family 22 member 12. (553 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (511 aa)
SLC22A11Solute carrier family 22 member 11. (404 aa)
SLC12A3Solute carrier family 12 member 3. (842 aa)
FOLR1Folate receptor alpha. (254 aa)
FOLR2Folate receptor beta isoform X1. (253 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (471 aa)
GP2Pancreatic secretory granule membrane major glycoprotein GP2. (502 aa)
LOC102749897A-kinase anchor protein 7 isoforms alpha and beta-like. (104 aa)
SLC39A4Zinc transporter ZIP4. (646 aa)
SLC3A1Neutral and basic amino acid transport protein rBAT isoform X1. (681 aa)
LOC102733028Large neutral amino acids transporter small subunit 2-like. (179 aa)
LOC102748904Augurin. (147 aa)
DYNC2LI1Cytoplasmic dynein 2 light intermediate chain 1. (350 aa)
GIFGastric intrinsic factor. (415 aa)
NEDD1Protein NEDD1-like isoform X1. (659 aa)
TMEM114Transmembrane protein 114. (223 aa)
MAL2Protein MAL2. (176 aa)
LOC102747715Sodium-dependent neutral amino acid transporter B(0)AT1-like. (521 aa)
SLC6A18Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (499 aa)
OCEL1occludin/ELL domain-containing protein 1. (262 aa)
LOC102737538UPF0740 protein C1orf192 homolog. (220 aa)
LOC102734325Monocarboxylate transporter 3-like. (185 aa)
LOC102734437Partitioning defective 3 homolog B-like. (523 aa)
SLC39A14Zinc transporter ZIP14 isoform X1. (490 aa)
SLC46A2Thymic stromal cotransporter homolog. (475 aa)
LOC102746933Monocarboxylate transporter 3-like. (271 aa)
SLC29A1Equilibrative nucleoside transporter 1. (456 aa)
AQP1Aquaporin-1 isoform X1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
CDHR2Cadherin-related family member 2. (1308 aa)
FXYD1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (92 aa)
LOC102749114Lactase-phlorizin hydrolase-like. (1500 aa)
LOC102736228Partitioning defective 3 homolog. (214 aa)
STX3Syntaxin-3; Belongs to the syntaxin family. (285 aa)
CETN2Centrin-2. (187 aa)
PARD6APartitioning defective 6 homolog alpha isoform X1. (346 aa)
UPK2Uroplakin-2. (184 aa)
C2CD2LC2 domain-containing protein 2-like. (545 aa)
USH1CHarmonin. (551 aa)
LOC102727281Annexin. (187 aa)
CCDC23Coiled-coil domain-containing protein 23. (66 aa)
LOC102738549Ileal sodium/bile acid cotransporter-like. (320 aa)
LOC102749234Large neutral amino acids transporter small subunit 2-like. (239 aa)
RDXRadixin isoform X1. (572 aa)
SLC29A4Equilibrative nucleoside transporter 4-like. (525 aa)
SLC6A20Sodium- and chloride-dependent transporter XTRP3. (514 aa)
LOC102738369Merlin-like. (110 aa)
KCNK1Potassium channel subfamily K member. (336 aa)
LOC102736444Uromodulin-like. (600 aa)
CIB3Calcium and integrin-binding family member 3 isoform X1. (187 aa)
LOC102730118V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
DUOX2Dual oxidase 2-like. (1225 aa)
LOC102726269Angiotensin-converting enzyme 2-like. (488 aa)
LOC102737868Canalicular multispecific organic anion transporter 1-like. (280 aa)
SLC7A1High affinity cationic amino acid transporter 1. (229 aa)
LOC102726878V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (393 aa)
UPK3AUroplakin-3a isoform X1. (287 aa)
SPEF1Sperm flagellar protein 1. (236 aa)
SLC26A9Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (752 aa)
LOC102747652Pappalysin-2-like. (301 aa)
TMEM235LOW QUALITY PROTEIN: transmembrane protein 235. (195 aa)
ABCG8LOW QUALITY PROTEIN: ATP-binding cassette, sub-family G (WHITE), member 8. (519 aa)
SLC5A12LOW QUALITY PROTEIN: solute carrier family 5 (Sodium/monocarboxylate cotransporter), member 12; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (453 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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