(17 nodes) Regulation of B cell differentiation network (Leptonychotes weddellii)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Known Interactions

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gene neighborhood

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Your Input:
	BCL6	B-cell lymphoma 6 protein. (706 aa)
	IL10	Interleukin-10. (178 aa)
	CARD11	Caspase recruitment domain-containing protein 11. (1146 aa)
	NCKAP1L	Nck-associated protein 1-like. (1134 aa)
	IL7	Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (158 aa)
	LOC102731864	Signal transducer and activator of transcription 5B-like. (353 aa)
	LOC102745948	CD27 antigen-like. (261 aa)
	TWF2	Toll-like receptor 9-like isoform X1. (1331 aa)
	STAT5A	Signal transducer and activator of transcription 5A. (464 aa)
	LOC102731636	Zinc finger protein Aiolos-like isoform X1. (262 aa)
	SLAMF8	SLAM family member 8. (280 aa)
	SFRP1	Secreted frizzled-related protein 1. (303 aa)
	MMP14	Matrix metalloproteinase-14. (582 aa)
	ZFP36L2	Zinc finger protein 36, C3H1 type-like 2-like. (491 aa)
	ZFP36L1	Zinc finger protein 36, C3H1 type-like 1 isoform X1. (338 aa)
	STAT5B	Signal transducer and activator of transcription 5B. (508 aa)
	IL2	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL6	IL10	A0A2U3Y0T0	A0A2U3XRS9	B-cell lymphoma 6 protein.	Interleukin-10.	0.495
BCL6	IL2	A0A2U3Y0T0	A0A2U3Y3E4	B-cell lymphoma 6 protein.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.525
BCL6	LOC102745948	A0A2U3Y0T0	A0A2U3Z5Z6	B-cell lymphoma 6 protein.	CD27 antigen-like.	0.545
BCL6	STAT5A	A0A2U3Y0T0	A0A2U3Z446	B-cell lymphoma 6 protein.	Signal transducer and activator of transcription 5A.	0.425
IL10	BCL6	A0A2U3XRS9	A0A2U3Y0T0	Interleukin-10.	B-cell lymphoma 6 protein.	0.495
IL10	IL2	A0A2U3XRS9	A0A2U3Y3E4	Interleukin-10.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.861
IL10	IL7	A0A2U3XRS9	A0A2U3X7L8	Interleukin-10.	Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family.	0.788
IL10	LOC102731864	A0A2U3XRS9	A0A2U3Z7Y1	Interleukin-10.	Signal transducer and activator of transcription 5B-like.	0.445
IL10	LOC102745948	A0A2U3XRS9	A0A2U3Z5Z6	Interleukin-10.	CD27 antigen-like.	0.571
IL10	STAT5A	A0A2U3XRS9	A0A2U3Z446	Interleukin-10.	Signal transducer and activator of transcription 5A.	0.527
IL10	STAT5B	A0A2U3XRS9	A0A2U3Y4J7	Interleukin-10.	Signal transducer and activator of transcription 5B.	0.445
IL10	TWF2	A0A2U3XRS9	A0A2U3Z4Z0	Interleukin-10.	Toll-like receptor 9-like isoform X1.	0.620
IL2	BCL6	A0A2U3Y3E4	A0A2U3Y0T0	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	B-cell lymphoma 6 protein.	0.525
IL2	IL10	A0A2U3Y3E4	A0A2U3XRS9	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	Interleukin-10.	0.861
IL2	IL7	A0A2U3Y3E4	A0A2U3X7L8	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family.	0.964
IL2	LOC102731864	A0A2U3Y3E4	A0A2U3Z7Y1	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	Signal transducer and activator of transcription 5B-like.	0.510
IL2	LOC102745948	A0A2U3Y3E4	A0A2U3Z5Z6	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	CD27 antigen-like.	0.628
IL2	STAT5A	A0A2U3Y3E4	A0A2U3Z446	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	Signal transducer and activator of transcription 5A.	0.739
IL2	STAT5B	A0A2U3Y3E4	A0A2U3Y4J7	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	Signal transducer and activator of transcription 5B.	0.510
IL2	TWF2	A0A2U3Y3E4	A0A2U3Z4Z0	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	Toll-like receptor 9-like isoform X1.	0.491