(18 nodes) Positive regulation of erythrocyte differentiation network (Leptonychotes weddellii)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

co-expression

protein homology

Your Input:
	ETS1	Protein C-ets-1-like isoform X1. (441 aa)
	STAT3	Signal transducer and activator of transcription 3-like. (424 aa)
	KAT7	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)
	LOC102731864	Signal transducer and activator of transcription 5B-like. (353 aa)
	LOC102745161	Signal transducer and activator of transcription 3-like. (301 aa)
	HIF1A	Hypoxia-inducible factor 1-alpha isoform X1. (823 aa)
	GATA1	Erythroid transcription factor. (413 aa)
	ISG15	Ubiquitin-like protein ISG15. (169 aa)
	FOXO3	Forkhead box protein O3. (672 aa)
	SMAP1	Stromal membrane-associated protein 1 isoform X1. (471 aa)
	NCKAP1L	Nck-associated protein 1-like. (1134 aa)
	INHBA	Inhibin beta A chain. (424 aa)
	MED1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1582 aa)
	PRMT1	Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
	LOC102747000	Uncharacterized protein C1orf186 homolog. (170 aa)
	ANKRD54	Ankyrin repeat domain-containing protein 54. (299 aa)
	FAM210B	Protein FAM210B. (192 aa)
	STAT5B	Signal transducer and activator of transcription 5B. (508 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ETS1	FOXO3	A0A2U3YA81	A0A2U3XDW8	Protein C-ets-1-like isoform X1.	Forkhead box protein O3.	0.476
ETS1	GATA1	A0A2U3YA81	A0A2U3Y495	Protein C-ets-1-like isoform X1.	Erythroid transcription factor.	0.512
ETS1	LOC102745161	A0A2U3YA81	A0A2U3Y4I5	Protein C-ets-1-like isoform X1.	Signal transducer and activator of transcription 3-like.	0.475
ETS1	STAT3	A0A2U3YA81	A0A2U3Z463	Protein C-ets-1-like isoform X1.	Signal transducer and activator of transcription 3-like.	0.475
FOXO3	ETS1	A0A2U3XDW8	A0A2U3YA81	Forkhead box protein O3.	Protein C-ets-1-like isoform X1.	0.476
FOXO3	HIF1A	A0A2U3XDW8	A0A2U3Y4G5	Forkhead box protein O3.	Hypoxia-inducible factor 1-alpha isoform X1.	0.787
FOXO3	LOC102745161	A0A2U3XDW8	A0A2U3Y4I5	Forkhead box protein O3.	Signal transducer and activator of transcription 3-like.	0.889
FOXO3	PRMT1	A0A2U3XDW8	A0A2U3YKY4	Forkhead box protein O3.	Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.901
FOXO3	STAT3	A0A2U3XDW8	A0A2U3Z463	Forkhead box protein O3.	Signal transducer and activator of transcription 3-like.	0.889
GATA1	ETS1	A0A2U3Y495	A0A2U3YA81	Erythroid transcription factor.	Protein C-ets-1-like isoform X1.	0.512
GATA1	PRMT1	A0A2U3Y495	A0A2U3YKY4	Erythroid transcription factor.	Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.424
HIF1A	FOXO3	A0A2U3Y4G5	A0A2U3XDW8	Hypoxia-inducible factor 1-alpha isoform X1.	Forkhead box protein O3.	0.787
HIF1A	LOC102745161	A0A2U3Y4G5	A0A2U3Y4I5	Hypoxia-inducible factor 1-alpha isoform X1.	Signal transducer and activator of transcription 3-like.	0.785
HIF1A	STAT3	A0A2U3Y4G5	A0A2U3Z463	Hypoxia-inducible factor 1-alpha isoform X1.	Signal transducer and activator of transcription 3-like.	0.785
ISG15	MED1	A0A2U3XMC4	A0A2U3YTF7	Ubiquitin-like protein ISG15.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.626
ISG15	STAT3	A0A2U3XMC4	A0A2U3Z463	Ubiquitin-like protein ISG15.	Signal transducer and activator of transcription 3-like.	0.434
LOC102731864	LOC102745161	A0A2U3Z7Y1	A0A2U3Y4I5	Signal transducer and activator of transcription 5B-like.	Signal transducer and activator of transcription 3-like.	0.869
LOC102731864	STAT3	A0A2U3Z7Y1	A0A2U3Z463	Signal transducer and activator of transcription 5B-like.	Signal transducer and activator of transcription 3-like.	0.852
LOC102731864	STAT5B	A0A2U3Z7Y1	A0A2U3Y4J7	Signal transducer and activator of transcription 5B-like.	Signal transducer and activator of transcription 5B.	0.947
LOC102745161	ETS1	A0A2U3Y4I5	A0A2U3YA81	Signal transducer and activator of transcription 3-like.	Protein C-ets-1-like isoform X1.	0.475