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ZBTB46 | Zinc finger and BTB domain-containing protein 46. (318 aa) | ||||
CASP8 | Caspase-8 isoform X1; Belongs to the peptidase C14A family. (486 aa) | ||||
RB1 | Retinoblastoma-associated protein. (846 aa) | ||||
TRIB1 | Tribbles homolog 1. (292 aa) | ||||
FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (218 aa) | ||||
HSF1 | Heat shock factor protein 1. (527 aa) | ||||
CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (547 aa) | ||||
PTPN2 | Tyrosine-protein phosphatase non-receptor type 2. (289 aa) | ||||
TGFB1 | Transforming growth factor beta-1. (261 aa) | ||||
IL34 | Interleukin-34. (236 aa) | ||||
C1QC | Complement C1q subcomponent subunit C. (245 aa) |