STRINGSTRING
F2R F2R PLCE1 PLCE1 SHOC2 SHOC2 MYOC MYOC LOC102728321 LOC102728321 ARHGEF28 ARHGEF28 SPRY3 SPRY3 SSX2IP SSX2IP RALGPS1 RALGPS1 BCL6 BCL6 ITGB1 ITGB1 ARFGAP1 ARFGAP1 SYNGAP1 SYNGAP1 CCDC125 CCDC125 KITLG KITLG LOC102733393 LOC102733393 SPRY4 SPRY4 CBL CBL LPAR6 LPAR6 LRRC59 LRRC59 SYDE2 SYDE2 GIT1 GIT1 LOC102738309 LOC102738309 LOC102742904 LOC102742904 KBTBD7 KBTBD7 SPRY1 SPRY1 TRIM67 TRIM67 KCTD10 KCTD10 CYTH4 CYTH4 RASGRP1 RASGRP1 EPS8L3 EPS8L3 ARHGDIA ARHGDIA DENND4B DENND4B STMN3 STMN3 P2RY8 P2RY8 LOC102725841 LOC102725841 CYTH2 CYTH2 STARD8 STARD8 CSF1 CSF1 IQSEC3 IQSEC3 RASGRF1 RASGRF1 SCAI SCAI KANK2 KANK2 NUP62 NUP62 LOC102740025 LOC102740025 LPAR4 LPAR4 GPR174 GPR174 LOC102740026 LOC102740026 P2RY10 P2RY10 DLC1 DLC1 LOC102736511 LOC102736511 KRAS KRAS RASA1 RASA1 LOC102726446 LOC102726446 CDC42SE2 CDC42SE2 RASGEF1A RASGEF1A CDC42SE1 CDC42SE1 LRRC7 LRRC7 STARD13 STARD13 FBXO8 FBXO8 ARF6 ARF6 FGF10 FGF10 ARHGAP24 ARHGAP24 RABGEF1 RABGEF1 SGSM3 SGSM3 ARHGAP42 ARHGAP42 GBF1 GBF1 SYNPO2L SYNPO2L IGF1 IGF1 PSD2 PSD2 TNFAIP1 TNFAIP1 ARHGAP35 ARHGAP35 RTN4R RTN4R CYTH3 CYTH3 STAMBP STAMBP IQSEC1 IQSEC1 LOC102729692 LOC102729692 PSD4 PSD4 NOTCH2 NOTCH2 NTRK1 NTRK1 LOC102735729 LOC102735729 ABRA ABRA GPR18 GPR18 FAM65C FAM65C LOC102744298 LOC102744298 LRRD1 LRRD1 LPAR1 LPAR1 LOC102728010 LOC102728010 ABL1 ABL1 LOC102731633 LOC102731633 OGT OGT EPS8L1 EPS8L1 NF1 NF1 LOC102730527 LOC102730527 GPR56 GPR56 LOC102736541 LOC102736541 LOC102730108 LOC102730108 GPR55 GPR55 ARAP3 ARAP3 ARHGEF25 ARHGEF25 LOC102728905 LOC102728905 LOC102728301 LOC102728301 DENND1A DENND1A FOXM1 FOXM1 LOC102744202 LOC102744202 LOC102727994 LOC102727994 LOC102750712 LOC102750712 LOC102726994 LOC102726994 LOC102725974 LOC102725974 SYDE1 SYDE1 LOC102746562 LOC102746562 MAPKAP1 MAPKAP1 F11R F11R FBP1 FBP1 LZTR1 LZTR1 FLCN FLCN PSD3 PSD3 RASA4 RASA4 LOC102742081 LOC102742081 ARFGEF1 ARFGEF1 LOC102731157 LOC102731157 NET1 NET1 LOC102750621 LOC102750621 F2RL2 F2RL2 F2RL1 F2RL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F2RProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
PLCE1Phosphoinositide phospholipase C. (2299 aa)
SHOC2Leucine-rich repeat protein SHOC-2 isoform X1. (582 aa)
MYOCMyocilin. (490 aa)
LOC102728321High affinity nerve growth factor receptor-like. (109 aa)
ARHGEF28Rho guanine nucleotide exchange factor 28. (1389 aa)
SPRY3Protein sprouty homolog 3. (288 aa)
SSX2IPAfadin- and alpha-actinin-binding protein. (614 aa)
RALGPS1Ras-specific guanine nucleotide-releasing factor RalGPS1. (426 aa)
BCL6B-cell lymphoma 6 protein. (706 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
ARFGAP1ADP-ribosylation factor GTPase-activating protein 1 isoform X2. (417 aa)
SYNGAP1ras/Rap GTPase-activating protein SynGAP. (1228 aa)
CCDC125Coiled-coil domain-containing protein 125. (513 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (274 aa)
LOC102733393Protein FAM65B-like. (563 aa)
SPRY4Protein sprouty homolog 4. (299 aa)
CBLE3 ubiquitin-protein ligase CBL. (910 aa)
LPAR6Lysophosphatidic acid receptor 6; Belongs to the G-protein coupled receptor 1 family. (344 aa)
LRRC59Leucine-rich repeat-containing protein 59. (261 aa)
SYDE2Rho GTPase-activating protein SYDE2. (1187 aa)
GIT1ARF GTPase-activating protein GIT1-like. (481 aa)
LOC102738309Muscle-related coiled-coil protein-like. (242 aa)
LOC102742904Uncharacterized protein MGC39606-like. (73 aa)
KBTBD7Kelch repeat and BTB domain-containing protein 7. (698 aa)
SPRY1Protein sprouty homolog 1 isoform X1. (319 aa)
TRIM67Tripartite motif-containing protein 67. (656 aa)
KCTD10BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3. (317 aa)
CYTH4Cytohesin-4. (394 aa)
RASGRP1RAS guanyl-releasing protein 1-like isoform X1. (366 aa)
EPS8L3LOW QUALITY PROTEIN: epidermal growth factor receptor kinase substrate 8-like protein 3. (586 aa)
ARHGDIARho GDP-dissociation inhibitor 1 isoform X1. (204 aa)
DENND4BDENN domain-containing protein 4B. (1485 aa)
STMN3Stathmin; Belongs to the stathmin family. (187 aa)
P2RY8P2Y purinoceptor 8; Belongs to the G-protein coupled receptor 1 family. (358 aa)
LOC102725841Microtubule-associated protein RP/EB family member 2-like. (124 aa)
CYTH2Cytohesin-2 isoform X1. (399 aa)
STARD8stAR-related lipid transfer protein 8. (1025 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (547 aa)
IQSEC3IQ motif and SEC7 domain-containing protein 3. (526 aa)
RASGRF1Ras-specific guanine nucleotide-releasing factor 1. (1165 aa)
SCAIProtein SCAI; Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity. (606 aa)
KANK2KN motif and ankyrin repeat domain-containing protein 2. (419 aa)
NUP62Nuclear pore glycoprotein p62. (525 aa)
LOC102740025Protein sprouty homolog 2-like isoform X1. (315 aa)
LPAR4Lysophosphatidic acid receptor 4; Belongs to the G-protein coupled receptor 1 family. (370 aa)
GPR174Probable G-protein coupled receptor 174. (330 aa)
LOC102740026Putative P2Y purinoceptor 10-like. (347 aa)
P2RY10Putative P2Y purinoceptor 10 isoform X1. (388 aa)
DLC1Rho GTPase-activating protein 7 isoform X1. (1527 aa)
LOC102736511Muscle-related coiled-coil protein-like. (150 aa)
KRASGTPase KRas isoform X2. (188 aa)
RASA1Ras GTPase-activating protein 1. (1039 aa)
LOC102726446Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like; Belongs to the PI3/PI4-kinase family. (235 aa)
CDC42SE2CDC42 small effector protein 2 isoform X1. (84 aa)
RASGEF1Aras-GEF domain-containing family member 1A. (480 aa)
CDC42SE1CDC42 small effector protein 1. (79 aa)
LRRC7Leucine-rich repeat-containing protein 7. (1537 aa)
STARD13stAR-related lipid transfer protein 13. (1123 aa)
FBXO8F-box only protein 8. (308 aa)
ARF6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa)
ARHGAP24Rho GTPase-activating protein 24 isoform X1. (750 aa)
RABGEF1Rab5 GDP/GTP exchange factor. (491 aa)
SGSM3Small G protein signaling modulator 3. (750 aa)
ARHGAP42Rho GTPase-activating protein 42. (874 aa)
GBF1Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1-like. (710 aa)
SYNPO2LSynaptopodin 2-like protein. (970 aa)
IGF1Insulin-like growth factor I isoform X1. (153 aa)
PSD2PH and SEC7 domain-containing protein 2-like. (350 aa)
TNFAIP1BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2. (316 aa)
ARHGAP35Rho GTPase-activating protein 35. (1500 aa)
RTN4RReticulon-4 receptor. (528 aa)
CYTH3Cytohesin-3. (270 aa)
STAMBPSTAM-binding protein isoform X1. (424 aa)
IQSEC1IQ motif and SEC7 domain-containing protein 1-like isoform X1. (1130 aa)
LOC102729692Ras-interacting protein 1-like. (208 aa)
PSD4PH and SEC7 domain-containing protein 4. (1012 aa)
NOTCH2Neurogenic locus notch homolog protein 2. (1238 aa)
NTRK1Tyrosine-protein kinase receptor. (592 aa)
LOC102735729MAP kinase-activating death domain protein-like. (373 aa)
ABRAActin-binding Rho-activating protein. (380 aa)
GPR18N-arachidonyl glycine receptor; Belongs to the G-protein coupled receptor 1 family. (331 aa)
FAM65CProtein FAM65C. (944 aa)
LOC102744298Uncharacterized protein MGC39606-like. (68 aa)
LRRD1Leucine-rich repeat and death domain-containing protein 1. (860 aa)
LPAR1Lysophosphatidic acid receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
LOC102728010LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 3-like. (525 aa)
ABL1Tyrosine-protein kinase ABL1-like. (312 aa)
LOC102731633Rho guanine nucleotide exchange factor 10-like. (410 aa)
OGTUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform X1. (1046 aa)
EPS8L1Epidermal growth factor receptor kinase substrate 8-like protein 1. (570 aa)
NF1Neurofibromin-like. (1269 aa)
LOC102730527Breakpoint cluster region protein-like. (172 aa)
GPR56G-protein coupled receptor 56 isoform X3; Belongs to the G-protein coupled receptor 2 family. (687 aa)
LOC102736541Cytohesin-1-like. (251 aa)
LOC102730108Neuropilin-1-like. (465 aa)
GPR55G-protein coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (320 aa)
ARAP3arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3. (1542 aa)
ARHGEF25Rho guanine nucleotide exchange factor 25 isoform X1. (619 aa)
LOC102728905KN motif and ankyrin repeat domain-containing protein 1-like. (167 aa)
LOC102728301PH and SEC7 domain-containing protein 1-like. (393 aa)
DENND1ADENN domain-containing protein 1A-like. (519 aa)
FOXM1Forkhead box protein M1 isoform X5. (692 aa)
LOC102744202Rho GTPase-activating protein 44-like. (155 aa)
LOC102727994Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1-like. (1181 aa)
LOC102750712Tyrosine-protein kinase SgK223-like. (673 aa)
LOC102726994Uracil nucleotide/cysteinyl leukotriene receptor-like; Belongs to the G-protein coupled receptor 1 family. (339 aa)
LOC102725974KN motif and ankyrin repeat domain-containing protein 1-like. (247 aa)
SYDE1Rho GTPase-activating protein SYDE1. (735 aa)
LOC102746562C-myc promoter-binding protein-like. (375 aa)
MAPKAP1Target of rapamycin complex 2 subunit MAPKAP1. (122 aa)
F11RJunctional adhesion molecule A. (298 aa)
FBP1Fructose-1,6-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
LZTR1Leucine-zipper-like transcriptional regulator 1. (840 aa)
FLCNFolliculin. (579 aa)
PSD3PH and SEC7 domain-containing protein 3. (974 aa)
RASA4Ras GTPase-activating protein 4 isoform X1. (801 aa)
LOC102742081BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1-like. (186 aa)
ARFGEF1Brefeldin A-inhibited guanine nucleotide-exchange protein 1. (1649 aa)
LOC102731157ARF GTPase-activating protein GIT1-like. (191 aa)
NET1Neuroepithelial cell-transforming gene 1 protein isoform X1. (596 aa)
LOC102750621Oligophrenin-1-like. (685 aa)
F2RL2Proteinase-activated receptor 3-like. (377 aa)
F2RL1Proteinase-activated receptor 2. (415 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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