STRINGSTRING
PEX2 PEX2 LOC102735317 LOC102735317 CD300A CD300A CDC73 CDC73 CAV1 CAV1 LOC102731342 LOC102731342 NUPR1 NUPR1 PAWR PAWR B4GALT7 B4GALT7 LOC102732879 LOC102732879 FBXO4 FBXO4 TP53 TP53 INCA1 INCA1 MORC3 MORC3 LOC102749901 LOC102749901 SFRP1 SFRP1 MED31 MED31 TRIM32 TRIM32 LOC102743045 LOC102743045 NF1 NF1 LOC102750901 LOC102750901 EMD EMD C1QL4 C1QL4 LOC102741471 LOC102741471
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PEX2Peroxisome biogenesis factor 2 isoform X1. (305 aa)
LOC102735317Dachshund homolog 1-like. (666 aa)
CD300ACMRF35-like molecule 8. (309 aa)
CDC73Parafibromin. (418 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
LOC102731342Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (670 aa)
NUPR1Nuclear protein 1 isoform X1. (82 aa)
PAWRPRKC apoptosis WT1 regulator protein. (290 aa)
B4GALT7Beta-1,4-galactosyltransferase 7-like. (327 aa)
LOC102732879Disabled homolog 2-interacting protein-like. (454 aa)
FBXO4F-box only protein 4. (387 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
INCA1Protein INCA1. (251 aa)
MORC3MORC family CW-type zinc finger protein 3. (900 aa)
LOC102749901Gamma-interferon-inducible-lysosomal thiol reductase-like. (252 aa)
SFRP1Secreted frizzled-related protein 1. (303 aa)
MED31Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (131 aa)
TRIM32E3 ubiquitin-protein ligase TRIM32-like isoform X1. (655 aa)
LOC102743045Disabled homolog 2-interacting protein-like. (326 aa)
NF1Neurofibromin-like. (1269 aa)
LOC102750901Mediator of RNA polymerase II transcription subunit 25-like. (746 aa)
EMDEmerin. (260 aa)
C1QL4Complement C1q-like protein 4. (238 aa)
LOC102741471Parafibromin-like. (141 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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