(24 nodes) Synaptic vesicle endocytosis network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SNCA	Alpha-synuclein; Belongs to the synuclein family. (140 aa)
	NLGN1	Neuroligin-1-like. (619 aa)
	LRRC1	Leucine-rich repeat-containing protein 1. (242 aa)
	KIAA1107	Uncharacterized protein KIAA1107 homolog. (1350 aa)
	SH3GL2	endophilin-A1. (352 aa)
	SNCB	Beta-synuclein; Belongs to the synuclein family. (94 aa)
	SNAP91	Clathrin coat assembly protein AP180 isoform X1. (899 aa)
	LOC102750621	Oligophrenin-1-like. (685 aa)
	DNAJC6	Putative tyrosine-protein phosphatase auxilin. (859 aa)
	PACSIN1	Protein kinase C and casein kinase substrate in neurons protein 1 isoform X1. (444 aa)
	NLGN3	Neuroligin-3 isoform X1. (848 aa)
	DNM3	Dynamin-3 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (865 aa)
	SYP	Synaptophysin. (313 aa)
	TBC1D24	TBC1 domain family member 24 isoform X1. (559 aa)
	SYT2	Synaptotagmin-2. (419 aa)
	CANX	Calnexin isoform X1. (594 aa)
	SNCG	Gamma-synuclein; Belongs to the synuclein family. (130 aa)
	SYNJ1	Synaptojanin-1 isoform X1. (1604 aa)
	DNM1	Dynamin-1 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa)
	SYT8	LOW QUALITY PROTEIN: synaptotagmin-8. (511 aa)
	LOC102745732	Leucine-rich repeat-containing protein 1-like. (92 aa)
	LOC102749626	Synaptotagmin-1-like. (303 aa)
	SYT5	Synaptotagmin-5 isoform X2. (386 aa)
	DENND1A	DENN domain-containing protein 1A-like. (519 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CANX	SYP	A0A2U3Y8B6	A0A2U3Y4D3	Calnexin isoform X1.	Synaptophysin.	0.430
DNAJC6	DNM1	A0A2U3XXN1	A0A2U3YKE7	Putative tyrosine-protein phosphatase auxilin.	Dynamin-1 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.765
DNAJC6	DNM3	A0A2U3XXN1	A0A2U3Y1K2	Putative tyrosine-protein phosphatase auxilin.	Dynamin-3 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.765
DNAJC6	SH3GL2	A0A2U3XXN1	A0A2U3XD79	Putative tyrosine-protein phosphatase auxilin.	endophilin-A1.	0.891
DNAJC6	SNAP91	A0A2U3XXN1	A0A2U3XR22	Putative tyrosine-protein phosphatase auxilin.	Clathrin coat assembly protein AP180 isoform X1.	0.762
DNAJC6	SYNJ1	A0A2U3XXN1	A0A2U3YDF9	Putative tyrosine-protein phosphatase auxilin.	Synaptojanin-1 isoform X1.	0.732
DNM1	DNAJC6	A0A2U3YKE7	A0A2U3XXN1	Dynamin-1 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Putative tyrosine-protein phosphatase auxilin.	0.765
DNM1	DNM3	A0A2U3YKE7	A0A2U3Y1K2	Dynamin-1 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Dynamin-3 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.968
DNM1	PACSIN1	A0A2U3YKE7	A0A2U3Y0E7	Dynamin-1 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Protein kinase C and casein kinase substrate in neurons protein 1 isoform X1.	0.428
DNM1	SH3GL2	A0A2U3YKE7	A0A2U3XD79	Dynamin-1 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	endophilin-A1.	0.909
DNM1	SNAP91	A0A2U3YKE7	A0A2U3XR22	Dynamin-1 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Clathrin coat assembly protein AP180 isoform X1.	0.541
DNM1	SYNJ1	A0A2U3YKE7	A0A2U3YDF9	Dynamin-1 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Synaptojanin-1 isoform X1.	0.861
DNM3	DNAJC6	A0A2U3Y1K2	A0A2U3XXN1	Dynamin-3 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Putative tyrosine-protein phosphatase auxilin.	0.765
DNM3	DNM1	A0A2U3Y1K2	A0A2U3YKE7	Dynamin-3 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Dynamin-1 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.968
DNM3	SH3GL2	A0A2U3Y1K2	A0A2U3XD79	Dynamin-3 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	endophilin-A1.	0.851
DNM3	SNAP91	A0A2U3Y1K2	A0A2U3XR22	Dynamin-3 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Clathrin coat assembly protein AP180 isoform X1.	0.539
LOC102745732	LRRC1	A0A2U3YZQ7	A0A2U3X9T6	Leucine-rich repeat-containing protein 1-like.	Leucine-rich repeat-containing protein 1.	0.900
LOC102749626	SH3GL2	A0A2U3Z0W3	A0A2U3XD79	Synaptotagmin-1-like.	endophilin-A1.	0.687
LOC102749626	SNAP91	A0A2U3Z0W3	A0A2U3XR22	Synaptotagmin-1-like.	Clathrin coat assembly protein AP180 isoform X1.	0.633
LOC102749626	SYNJ1	A0A2U3Z0W3	A0A2U3YDF9	Synaptotagmin-1-like.	Synaptojanin-1 isoform X1.	0.471